Mutations in Coding Sequences of Structural Genes

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Questions and Answers

What type of mutation changes a normal codon to a termination codon?

  • Frameshift mutation
  • Missense mutation
  • Silent mutation
  • Nonsense mutation (correct)

Which type of mutation does not alter the amino acid sequence of the polypeptide?

  • Nonsense mutation
  • Missense mutation
  • Frameshift mutation
  • Silent mutation (correct)

What is the effect of a frameshift mutation on the amino acid sequence?

  • It changes a single amino acid
  • It has no effect on the amino acid sequence
  • It produces a completely different amino acid sequence (correct)
  • It results in premature termination

Which type of mutation results in a different amino acid being incorporated into a polypeptide?

<p>Missense mutation (B)</p> Signup and view all the answers

What type of mutation is sickle-cell anemia an example of?

<p>Missense mutation (B)</p> Signup and view all the answers

What is the term for a mutation that changes the wild-type genotype into a new variation?

<p>Forward mutation (A)</p> Signup and view all the answers

What is a point mutation?

<p>A change in a single base pair (A)</p> Signup and view all the answers

What is a transition in a point mutation?

<p>A change of a pyrimidine to another pyrimidine (D)</p> Signup and view all the answers

What is a result of the addition or deletion of short sequences of DNA in a gene?

<p>A frameshift mutation (C)</p> Signup and view all the answers

What type of mutation is a substitution of a single nucleotide that changes the amino acid sequence of a protein?

<p>Missense mutation (C)</p> Signup and view all the answers

What type of mutation is a substitution of a single nucleotide that does not change the amino acid sequence of a protein?

<p>Silent mutation (D)</p> Signup and view all the answers

What type of mutation is a substitution of a single nucleotide that results in a premature stop codon?

<p>Nonsense mutation (D)</p> Signup and view all the answers

What type of mutation decreases the chances of survival?

<p>Deleterious mutation (C)</p> Signup and view all the answers

Which type of mutation affects the phenotype only under a defined set of conditions?

<p>Conditional mutation (D)</p> Signup and view all the answers

What is the term for a second mutation that affects the phenotypic expression of another mutation?

<p>Suppressor mutation (A)</p> Signup and view all the answers

What type of mutation occurs when a mutation alters the sequence within a promoter?

<p>Up promoter mutation (D)</p> Signup and view all the answers

What is the term for a mutation that is located in the same gene as the first mutation?

<p>Intragenic mutation (C)</p> Signup and view all the answers

What is the term for a mutation that occurs in cells that give rise to gametes?

<p>Germ-line mutation (A)</p> Signup and view all the answers

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