Mutations in Coding Sequences of Structural Genes
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Questions and Answers

What type of mutation changes a normal codon to a termination codon?

  • Frameshift mutation
  • Missense mutation
  • Silent mutation
  • Nonsense mutation (correct)

    • Which type of mutation does not alter the amino acid sequence of the polypeptide?

  • Nonsense mutation
  • Missense mutation
  • Frameshift mutation
  • Silent mutation (correct)

    • What is the effect of a frameshift mutation on the amino acid sequence?

  • It changes a single amino acid
  • It has no effect on the amino acid sequence
  • It produces a completely different amino acid sequence (correct)
  • It results in premature termination

    • Which type of mutation results in a different amino acid being incorporated into a polypeptide?

    <p>Missense mutation</p> Signup and view all the answers

    What type of mutation is sickle-cell anemia an example of?

    <p>Missense mutation</p> Signup and view all the answers

    What is the term for a mutation that changes the wild-type genotype into a new variation?

    <p>Forward mutation</p> Signup and view all the answers

    What is a point mutation?

    <p>A change in a single base pair</p> Signup and view all the answers

    What is a transition in a point mutation?

    <p>A change of a pyrimidine to another pyrimidine</p> Signup and view all the answers

    What is a result of the addition or deletion of short sequences of DNA in a gene?

    <p>A frameshift mutation</p> Signup and view all the answers

    What type of mutation is a substitution of a single nucleotide that changes the amino acid sequence of a protein?

    <p>Missense mutation</p> Signup and view all the answers

    What type of mutation is a substitution of a single nucleotide that does not change the amino acid sequence of a protein?

    <p>Silent mutation</p> Signup and view all the answers

    What type of mutation is a substitution of a single nucleotide that results in a premature stop codon?

    <p>Nonsense mutation</p> Signup and view all the answers

    What type of mutation decreases the chances of survival?

    <p>Deleterious mutation</p> Signup and view all the answers

    Which type of mutation affects the phenotype only under a defined set of conditions?

    <p>Conditional mutation</p> Signup and view all the answers

    What is the term for a second mutation that affects the phenotypic expression of another mutation?

    <p>Suppressor mutation</p> Signup and view all the answers

    What type of mutation occurs when a mutation alters the sequence within a promoter?

    <p>Up promoter mutation</p> Signup and view all the answers

    What is the term for a mutation that is located in the same gene as the first mutation?

    <p>Intragenic mutation</p> Signup and view all the answers

    What is the term for a mutation that occurs in cells that give rise to gametes?

    <p>Germ-line mutation</p> Signup and view all the answers

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