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Questions and Answers
Which type of muscle tissue is primarily under voluntary control?
Which type of muscle tissue is primarily under voluntary control?
Which of the following muscles is striated and involuntary?
Which of the following muscles is striated and involuntary?
What is the primary function of the muscular system in stabilizing body positions?
What is the primary function of the muscular system in stabilizing body positions?
What is the structure of skeletal muscle fibers?
What is the structure of skeletal muscle fibers?
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Cardiac muscle tissue is characterized by which of the following features?
Cardiac muscle tissue is characterized by which of the following features?
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What component is NOT part of skeletal muscle tissue?
What component is NOT part of skeletal muscle tissue?
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Which type of muscle tissue is found in the walls of internal organs?
Which type of muscle tissue is found in the walls of internal organs?
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What characteristic distinguishes smooth muscle tissue?
What characteristic distinguishes smooth muscle tissue?
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What triggers the muscle action potential in the motor end plate?
What triggers the muscle action potential in the motor end plate?
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What role does calcium ion (Ca2+) play in muscle contraction?
What role does calcium ion (Ca2+) play in muscle contraction?
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What happens to acetylcholine in the synaptic cleft after triggering a muscle action potential?
What happens to acetylcholine in the synaptic cleft after triggering a muscle action potential?
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What is the consequence of elevated calcium levels in the sarcoplasm?
What is the consequence of elevated calcium levels in the sarcoplasm?
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During muscle relaxation, what restores low levels of calcium in the sarcoplasm?
During muscle relaxation, what restores low levels of calcium in the sarcoplasm?
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What initiates the opening of calcium release channels in the sarcoplasmic reticulum?
What initiates the opening of calcium release channels in the sarcoplasmic reticulum?
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What primarily happens during the contraction phase of muscle action?
What primarily happens during the contraction phase of muscle action?
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Which structure directly releases acetylcholine into the synaptic cleft?
Which structure directly releases acetylcholine into the synaptic cleft?
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What begins the contraction of skeletal muscle?
What begins the contraction of skeletal muscle?
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What role does calcium play during muscle contraction?
What role does calcium play during muscle contraction?
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Which statement best describes the sliding filament theory?
Which statement best describes the sliding filament theory?
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What happens during the power stroke phase of muscle contraction?
What happens during the power stroke phase of muscle contraction?
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What is the result of acetylcholinesterase breaking down ACh?
What is the result of acetylcholinesterase breaking down ACh?
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What occurs immediately after the release of calcium from the sarcoplasmic reticulum?
What occurs immediately after the release of calcium from the sarcoplasmic reticulum?
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What is necessary for the continuation of the contraction cycle?
What is necessary for the continuation of the contraction cycle?
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Which phase represents the detachment of cross-bridges?
Which phase represents the detachment of cross-bridges?
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What triggers the release of acetylcholine at the neuromuscular junction?
What triggers the release of acetylcholine at the neuromuscular junction?
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What is the primary function of myosin heads during muscle contraction?
What is the primary function of myosin heads during muscle contraction?
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What primarily influences the amount of tension produced by muscle fibers?
What primarily influences the amount of tension produced by muscle fibers?
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What are the three phases of a muscle twitch?
What are the three phases of a muscle twitch?
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Which situation describes incomplete tetanus?
Which situation describes incomplete tetanus?
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How many muscle fibers does a motor neuron typically connect to in a muscle?
How many muscle fibers does a motor neuron typically connect to in a muscle?
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What is the effect of fatigue on muscle contraction?
What is the effect of fatigue on muscle contraction?
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What characterizes isometric contractions?
What characterizes isometric contractions?
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What type of muscle fiber contracts more quickly but fatigues rapidly?
What type of muscle fiber contracts more quickly but fatigues rapidly?
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Which type of muscle fiber is characterized by a high concentration of myoglobin?
Which type of muscle fiber is characterized by a high concentration of myoglobin?
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What is the term used for the enlargement of muscle fibers due to training?
What is the term used for the enlargement of muscle fibers due to training?
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Which muscles are referred to as white muscles?
Which muscles are referred to as white muscles?
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What is the primary function of pacemaker cells in the heart?
What is the primary function of pacemaker cells in the heart?
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What type of muscle tissue is not striated and is found in internal organs?
What type of muscle tissue is not striated and is found in internal organs?
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Which characteristic is true for skeletal muscle tissue?
Which characteristic is true for skeletal muscle tissue?
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What is the role of tropomyosin in muscle contraction?
What is the role of tropomyosin in muscle contraction?
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Which of the following describes the organization of connective tissues in skeletal muscle?
Which of the following describes the organization of connective tissues in skeletal muscle?
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What is the starting point for skeletal muscle contraction?
What is the starting point for skeletal muscle contraction?
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What is released from synaptic vesicles at the neuromuscular junction?
What is released from synaptic vesicles at the neuromuscular junction?
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Which type of muscle tissue primarily exists in the heart and is involuntary?
Which type of muscle tissue primarily exists in the heart and is involuntary?
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What is the role of calcium ions in muscle contraction?
What is the role of calcium ions in muscle contraction?
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What function does skeletal muscle NOT typically perform?
What function does skeletal muscle NOT typically perform?
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What initial process occurs after acetylcholine binds to its receptors at the neuromuscular junction?
What initial process occurs after acetylcholine binds to its receptors at the neuromuscular junction?
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What is the composition of thick muscle filaments?
What is the composition of thick muscle filaments?
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Which muscle component helps in transmitting action potentials into the muscle fibers?
Which muscle component helps in transmitting action potentials into the muscle fibers?
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Study Notes
Musculoskeletal System (Part 2)
- Learning Outcomes: Students will be able to list muscle types and their characteristics, understand action potentials and neuromuscular junctions, and describe muscle contraction and relaxation.
- Functions of Muscular System: Muscles produce movement, stabilize body positions, move substances within the body, produce heat, support soft tissues, guard entrances/exits of the body, and provide nutrient reserves.
- Types of Muscle Tissues: Skeletal, cardiac, and smooth muscles.
- Skeletal Muscle Tissue: Primarily attached to bones, it is striated and voluntary.
- Cardiac Muscle Tissue: Forms the heart wall; striated and involuntary.
- Smooth Muscle Tissue: Located mainly in internal organs; non-striated and involuntary.
- Skeletal Muscle Tissue Details: The most abundant tissue in the human body, under voluntary control. Skeletal muscle tissue contains skeletal muscle cells, connective tissue, blood vessels, and nerves. Each cell is called a skeletal muscle fiber, which is a long, cylindrical cell containing multiple nuclei and striations (alternating light and dark bands). Muscle fibers bind together and with connective tissue, nerves, and blood vessels to form bundles, which further combine to form muscles.
- Cardiac Muscle Tissue Details: Found only in the heart, composed of cardiac muscle cells (cardiocytes), striated, and usually contain a centrally located single nucleus. Not under voluntary control; a bundle of specialized muscle cells (pacemaker cells) in the upper part of the heart sends electrical signals through cardiac tissue, causing the heart to contract and pump blood.
- Smooth Muscle Tissue Details: Found in internal organs and blood vessel walls, spindle-shaped, contains a single nucleus, non-striated, and involuntary. The contractions in smooth muscles move food through the digestive tract, control blood flow, and adjust pupil size.
- Anatomy of Skeletal Muscle: The organization of connective tissues: Epimysium surrounds muscle; perimysium sheathes bundles of muscle fibers; perimysium and epimysium contain blood vessels and nerves; endomysium covers individual muscle fibers; tendons connect muscle to bone or another muscle.
Skeletal Muscle Fiber Structures
- Sarcolemma (cell membrane)
- Sarcoplasm (muscle cell cytoplasm)
- Sarcoplasmic Reticulum (modified ER) with high Ca2+ concentration
- T-tubules and myofibrils aid in contraction
- Sarcomeres - regular arrangement of myofibrils
Muscle Fiber Components
- Thin Filaments: Actin, tropomyosin (covers actin's active sites), and troponin (holds tropomyosin in place and binding site for Ca2+).
- Thick Filaments: Myosin fibers (with tail and globular heads) that form cross-bridges during contraction. Interactions between actin and myosin are prevented by tropomyosin in a resting state.
Muscle Fiber Contraction
- Triggered by nerve impulses at the neuromuscular junction.
- Action potential travels along the sarcolemma, to the T-tubules, triggering the release of calcium ions from the sarcoplasmic reticulum.
- Calcium binds to troponin, causing tropomyosin to shift, exposing actin binding sites.
- Myosin heads attach to actin and contract (power stroke).
- ATP binding to myosin heads allows cross-bridges to detach.
Sliding Filament Theory
- Thick and thin filaments slide past each other during contraction.
- Cyclical process beginning with calcium release from the sarcoplasmic reticulum.
- Calcium binds to troponin, shifting tropomyosin.
- Myosin heads form cross bridges and pull actin filaments closer.
- ATP allows the release of cross bridges.
Muscle Contraction & Relaxation
- Action potential along T-tubules triggers calcium release from sarcoplasmic reticulum cisternae. Attachment sites are exposed and cross-bridge formation occurs.
- ATP binds myosin head causing cross-bridge release and recovery stroke.
- Acetylcholinesterase breaks down acetylcholine, limiting the duration of contraction, facilitating relaxation.
Tension Production by Muscle Fibers
- Tension depends on the number of cross-bridges formed.
- Skeletal muscle contracts most effectively over a narrow range of resting lengths.
- "Twitch" is a single contraction-relaxation cycle in response to a stimulus (lag, contraction, and relaxation phases) - repeated stimulation leading to summation.
Summation
- Repeated stimulation before relaxation leads to wave summation (a second twitch added to the first).
- Incomplete tetanus (muscle never fully relaxes).
- Complete tetanus (relaxation phase eliminated).
Motor Units and Recruitment
- Motor units are composed of a motor neuron and the muscle fibers it stimulates.
- A motor neuron typically contacts about 150 muscle fibers.
- Precision of movement depends on the number of small motor units involved. Strength of contraction relies on the size of motor units activated. Muscles controlling fine movements have fewer fibers per unit (e.g., eyes); those controlling large movements have more.
Muscle Fatigue
- Muscle fibers use ATP faster than they can produce it, leading to weaker contractions.
- New ATP binding is vital for breaking down cross-bridges.
- Examples: Muscle cramps, rigor mortis (stiffness after death).
Types of Muscle Contractions
- Isometric: Tension increases but the muscle length remains constant.
- Isotonic: Tension increases, and the muscle length changes. Resistance and speed of contraction are inversely related.
Muscle Performance
- Fast fibers (type II myosin): Large diameter, densely packed myofibrils, large glycogen reserves, relatively few mitochondria, rapid contractions, fatigue quickly (white muscle).
- Slow fibers (type I myosin): Half the diameter of fast fibers, take longer to contract, abundant mitochondria, extensive capillaries, high myoglobin concentrations, long-duration contractions, greater resistance to fatigue (red muscle).
Muscle Performance & Fiber Distribution
- Pale muscle (dominated by fast fibers) = white muscle. Dark muscle (dominated by slow fibers and myoglobin) = red muscle.
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Description
Test your knowledge on the muscular system with this quiz. Explore topics such as muscle tissue types, functionality, and structural characteristics. Challenge yourself with questions on voluntary and involuntary muscles, as well as their locations in the body.