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Questions and Answers
Which type of muscle tissue is categorized as involuntary?
Which type of muscle tissue is categorized as involuntary?
What is the ability of muscle to respond to stimuli called?
What is the ability of muscle to respond to stimuli called?
Which connective tissue sheath directly surrounds individual muscle fibers?
Which connective tissue sheath directly surrounds individual muscle fibers?
Which of the following is NOT a function of muscles?
Which of the following is NOT a function of muscles?
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What role do nerves play in skeletal muscle function?
What role do nerves play in skeletal muscle function?
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Which characteristic of muscle refers to its ability to return to its resting length after being stretched?
Which characteristic of muscle refers to its ability to return to its resting length after being stretched?
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Which of the following muscle types is under conscious control?
Which of the following muscle types is under conscious control?
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What is the dense irregular connective tissue that surrounds an entire skeletal muscle called?
What is the dense irregular connective tissue that surrounds an entire skeletal muscle called?
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What primarily affects the force of muscle contractions?
What primarily affects the force of muscle contractions?
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Which factor does NOT influence force of muscle contraction?
Which factor does NOT influence force of muscle contraction?
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Which statement regarding muscle fiber recruitment is true?
Which statement regarding muscle fiber recruitment is true?
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How does the relative size of muscle fibers affect muscle contraction?
How does the relative size of muscle fibers affect muscle contraction?
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At what degree of muscle stretch do sarcomeres generate maximum force?
At what degree of muscle stretch do sarcomeres generate maximum force?
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Which factor does NOT influence the speed of muscle contraction?
Which factor does NOT influence the speed of muscle contraction?
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What role does the frequency of stimulation play in muscle contraction?
What role does the frequency of stimulation play in muscle contraction?
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What happens when a sarcomere is stretched beyond 120% of its resting length?
What happens when a sarcomere is stretched beyond 120% of its resting length?
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What is the primary attachment point of a muscle that is less movable?
What is the primary attachment point of a muscle that is less movable?
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What type of attachment is considered the most common for muscles?
What type of attachment is considered the most common for muscles?
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Which structural feature of skeletal muscle accounts for approximately 80% of the muscle cell volume?
Which structural feature of skeletal muscle accounts for approximately 80% of the muscle cell volume?
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What is the smallest contractile unit of a skeletal muscle fiber?
What is the smallest contractile unit of a skeletal muscle fiber?
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What feature is characteristic of the A band in myofibrils?
What feature is characteristic of the A band in myofibrils?
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Which of the following is NOT a component of the myofilament structure within a sarcomere?
Which of the following is NOT a component of the myofilament structure within a sarcomere?
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What provides the resistance against abrasion from rough bony projections in muscles?
What provides the resistance against abrasion from rough bony projections in muscles?
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What structure serves as the muscle fiber plasma membrane?
What structure serves as the muscle fiber plasma membrane?
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What initiates the process of cross bridge formation in muscle contraction?
What initiates the process of cross bridge formation in muscle contraction?
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What distinguishes smooth muscle from skeletal muscle regarding connective tissue?
What distinguishes smooth muscle from skeletal muscle regarding connective tissue?
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During the working stroke of the cross bridge cycle, what movement occurs?
During the working stroke of the cross bridge cycle, what movement occurs?
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In smooth muscle, how is calcium primarily sourced for contraction?
In smooth muscle, how is calcium primarily sourced for contraction?
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What causes the detachment of the myosin head from the actin filament?
What causes the detachment of the myosin head from the actin filament?
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What is the arrangement of thick and thin filaments in smooth muscle?
What is the arrangement of thick and thin filaments in smooth muscle?
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What role does Ca2+ play in muscle contraction?
What role does Ca2+ play in muscle contraction?
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What is the role of calmodulin in smooth muscle?
What is the role of calmodulin in smooth muscle?
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What is the primary mechanism for the cessation of contraction in muscle fibers?
What is the primary mechanism for the cessation of contraction in muscle fibers?
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Which statement accurately describes the electrical connections between smooth muscle fibers?
Which statement accurately describes the electrical connections between smooth muscle fibers?
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Which of the following correctly describes the cocking of the myosin head?
Which of the following correctly describes the cocking of the myosin head?
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What must occur before cross bridge cycling begins?
What must occur before cross bridge cycling begins?
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Why does smooth muscle have a greater power despite having fewer thick filaments?
Why does smooth muscle have a greater power despite having fewer thick filaments?
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What defines the bulging appearance of smooth muscle during contraction?
What defines the bulging appearance of smooth muscle during contraction?
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What is the sequence of events at the neuromuscular junction that leads to muscle contraction?
What is the sequence of events at the neuromuscular junction that leads to muscle contraction?
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Which feature is absent in smooth muscle that is typically found in skeletal muscle?
Which feature is absent in smooth muscle that is typically found in skeletal muscle?
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What is the role of calmodulin in smooth muscle contraction?
What is the role of calmodulin in smooth muscle contraction?
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How does smooth muscle contraction differ from skeletal muscle contraction?
How does smooth muscle contraction differ from skeletal muscle contraction?
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Which statement is true about the mechanism of relaxation in smooth muscle?
Which statement is true about the mechanism of relaxation in smooth muscle?
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What characterizes unitary smooth muscle?
What characterizes unitary smooth muscle?
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What is a key function of the stress-relaxation response in smooth muscle?
What is a key function of the stress-relaxation response in smooth muscle?
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Which component is primarily responsible for initiating contraction in smooth muscle?
Which component is primarily responsible for initiating contraction in smooth muscle?
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What distinguishes multiunit smooth muscle from unitary smooth muscle?
What distinguishes multiunit smooth muscle from unitary smooth muscle?
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What mechanism stops contraction in smooth muscle?
What mechanism stops contraction in smooth muscle?
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What role does ATP play during smooth muscle contraction?
What role does ATP play during smooth muscle contraction?
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How do neural stimuli affect smooth muscle contraction?
How do neural stimuli affect smooth muscle contraction?
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Study Notes
Muscle Tissue Overview
- Muscle tissue is responsible for movement, posture maintenance, and heat production.
- Three types of muscle tissue exist: skeletal, cardiac, and smooth.
Types of Muscle Tissue
-
Skeletal muscle: Voluntary muscle attached to bones, responsible for locomotion and manipulation.
- Cells (fibers) are long, cylindrical, multinucleated, and striated.
- Controlled consciously.
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Cardiac muscle: Involuntary muscle found only in the heart.
- Cells are branching, uni- or binucleate, and striated.
- Controlled involuntarily.
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Smooth muscle: Involuntary muscle found in the walls of hollow organs (except the heart).
- Cells are spindle-shaped, uninucleate, and non-striated.
- Controlled involuntarily
Muscle Characteristics
- Excitability (responsiveness): Ability to receive and respond to stimuli.
- Contractility: Ability to shorten forcibly when adequately stimulated.
- Extensibility: Ability to be stretched.
- Elasticity: Ability to recoil and resume resting length after stretching.
Skeletal Muscle Anatomy
- Nerve and blood supply: Skeletal muscle requires substantial oxygen and nutrients, and waste removal during contraction. Nerves control each fiber separately, enabling precise control.
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Connective tissue sheaths: Sheaths of connective tissue (epimysium, perimysium, and endomysium) surround and support individual muscle fibers and groups of fibers (fascicles).
- Epimysium: Dense irregular connective tissue surrounding the entire muscle.
- Perimysium: Fibrous connective tissue surrounding fascicles (bundles of muscle fibers).
- Endomysium: Fine areolar connective tissue wrapping each muscle fiber.
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Attachments: Muscles attach to bones in at least two points:
- Origin: Attachment to the less movable bone.
- Insertion: Attachment to the movable bone. -Direct (fleshy): Epimysium fused to periosteum. -Indirect: Connective tissue wrappings extend beyond the muscle as a tendon or aponeurosis.
Skeletal Muscle Microscopic Anatomy
- Sarcolemma: Muscle fiber's plasma membrane.
- Sarcoplasm: Muscle fiber's cytoplasm, containing glycogen for energy storage and myoglobin for oxygen storage.
- Myofibrils: Densely packed, rod-like elements that run the length of the muscle fiber.
- Sarcomeres: Smallest contractile unit of a muscle fiber, organized as repeating sections along myofibrils.
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Myofilaments: Actin (thin) and myosin (thick) filaments within sarcomeres, responsible for the sliding filament mechanism of contraction.
- Actin filaments: Composed of actin, troponin, and tropomyosin.
- Myosin filaments: Composed of the myosin protein with heads that bind to actin.
- Sarcoplasmic reticulum (SR): Smooth endoplasmic reticulum surrounding myofibrils, storing and releasing calcium ions (Ca2+).
- T tubules: Infoldings of the sarcolemma, extending deep into the muscle fiber to conduct electrical impulses to the SR.
Excitation-Contraction Coupling
- Sequence of events linking electrical stimulation to muscle contraction.
- Action potentials travel along the sarcolemma and down the T tubules to stimulate Ca2+ release from the SR.
- Ca2+ binding to troponin exposes myosin-binding sites on actin, leading to cross-bridge formation.
Sliding Filament Model of Muscle Contraction
- Overlapping actin and myosin filaments slide past each other during contraction.
- Actin filaments move towards the center of the sarcomere (M line).
- Z discs move closer together, causing sarcomere shortening.
Cross-Bridge Cycling
- Cycle of events during muscle contraction.
- Cross-bridge formation: Myosin head binds to actin.
- Power stroke: Myosin head pivots, pulling actin.
- Cross-bridge detachment: ATP binds to myosin, causing detachment from actin.
- Myosin reactivation: ATP hydrolysis "recocks" myosin head.
ATP Usage in Muscle Contraction
- ATP required for cross-bridge cycling, Ca2+ pump, and other cellular activities.
- ATP is regenerated quickly through three mechanisms:
- Creatine phosphate (CP) phosphorylation: Provides rapid ATP regeneration.
- Anaerobic pathway (glycolysis): Generates ATP without oxygen but produces lactic acid.
- Aerobic respiration: Provides most ATP during prolonged activity but requires oxygen.
Muscle Fatigue
- Physiologic inability to contract despite continued stimulation.
- Causes include: ionic imbalances, insufficient ATP, decreased glycogen, increased inorganic phosphate, and magnesium.
EPOC (Excess Postexercise Oxygen Consumption)
- Extra oxygen needed to replenish ATP and CP, convert lactic acid, and resynthesis glycogen.
Types of Contractions
-
Isotonic contractions: Muscle changes length and moves a load.
- Concentric: Muscle shortens and does work (e.g., lifting a weight).
- Eccentric: Muscle lengthens while maintaining tension (e.g., lowering a weight).
- Isometric contractions: Muscle develops tension but does not change length (e.g., pushing against a wall).
Other Important Factors
- Motor units: A motor neuron and all the muscle fibers it innervates.
- Muscle twitch: Simplest contraction resulting from a muscle fiber's response to a single action potential.
- Graded muscle responses: Variations in the degree of muscle contraction, including temporal (wave) summation and recruitment, crucial for controlling skeletal movement.
- Muscle fiber types: Skeletal muscle fibers are categorized by their speed of contraction (slow or fast) and primary metabolic pathways (oxidative or glycolytic); different types are specialized for different functions.
- Smooth muscle: Differs from skeletal muscle in structure (e.g., no striations, less developed SR), mechanism of contraction (e.g., Ca2+ binding to calmodulin rather than troponin), and functional characteristics (e.g. stress-relaxation response).
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Test your knowledge on muscle tissue with this engaging quiz designed for Biology Class 11 students. You'll explore topics like muscle types, functions, and characteristics, helping you reinforce your understanding of this fundamental subject. Perfect for exam preparation or self-assessment!