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Questions and Answers
What is the primary role of the sarcoplasmic reticulum in muscle fibres?
What is the primary role of the sarcoplasmic reticulum in muscle fibres?
- To serve as the primary energy source for muscles
- To provide structural support to muscle fibres
- To store calcium ions necessary for muscle contraction (correct)
- To store proteins needed for muscle contraction
Which statement accurately describes the structure of muscle fibres?
Which statement accurately describes the structure of muscle fibres?
- Muscle fibres contain only one nucleus
- Muscle fibres are aligned in a circular pattern
- Muscle fibres are completely isolated from blood capillaries
- Muscle fibres consist of parallelly arranged myofilaments (correct)
What distinguishes the I-band from the A-band in striated muscle myofibrils?
What distinguishes the I-band from the A-band in striated muscle myofibrils?
- The I-band is made up of actin filaments, whereas the A-band contains myosin (correct)
- The A-band is isotropic while the I-band is anisotropic
- The I-band contains myosin while the A-band contains actin
- The I-band appears darker than the A-band
What is the connective tissue layer that holds muscle bundles together called?
What is the connective tissue layer that holds muscle bundles together called?
Why are muscle fibres referred to as a syncitium?
Why are muscle fibres referred to as a syncitium?
What term is used to describe the first seven pairs of ribs?
What term is used to describe the first seven pairs of ribs?
Which pairs of ribs are classified as vertebrochondral ribs?
Which pairs of ribs are classified as vertebrochondral ribs?
What characteristic distinguishes floating ribs from other types of ribs?
What characteristic distinguishes floating ribs from other types of ribs?
How many bones make up each limb in the appendicular skeleton?
How many bones make up each limb in the appendicular skeleton?
What type of cartilage connects the true ribs to the sternum?
What type of cartilage connects the true ribs to the sternum?
What is the role of the globular head in the myosin filament?
What is the role of the globular head in the myosin filament?
Which part of the meromyosin structure is referred to as the 'heavy meromyosin' (HMM)?
Which part of the meromyosin structure is referred to as the 'heavy meromyosin' (HMM)?
How is muscle contraction initiated?
How is muscle contraction initiated?
What does the sliding filament theory explain?
What does the sliding filament theory explain?
What is the significance of the neuromuscular junction?
What is the significance of the neuromuscular junction?
Which of the following bones is NOT part of the forelimb?
Which of the following bones is NOT part of the forelimb?
What forms the pelvic girdle?
What forms the pelvic girdle?
What articulates with the head of the humerus to form the shoulder joint?
What articulates with the head of the humerus to form the shoulder joint?
Which of the following correctly describes the number of phalanges in the human hand?
Which of the following correctly describes the number of phalanges in the human hand?
Which statement accurately describes the clavicle?
Which statement accurately describes the clavicle?
What type of joint does not allow any movement?
What type of joint does not allow any movement?
Which joint type is characterized by a fluid-filled synovial cavity?
Which joint type is characterized by a fluid-filled synovial cavity?
Which of the following joints allows for limited movement?
Which of the following joints allows for limited movement?
What is the primary function of joints in the body?
What is the primary function of joints in the body?
Which of these is a type of synovial joint?
Which of these is a type of synovial joint?
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Study Notes
Skeletal Muscle Structure
- Organized skeletal muscle contains muscle bundles, known as fascicles, held together by fascia, a collagenous connective tissue.
- Each fascicle consists of numerous muscle fibers (muscle cells) surrounding a plasma membrane called the sarcolemma.
- Muscle fibers contain multiple nuclei and are filled with sarcoplasm, which houses the endoplasmic reticulum, known as the sarcoplasmic reticulum, functioning as a calcium ion reservoir.
- Myofibrils, abundant in muscle fibers, are composed of filaments that display light and dark bands; the light bands (I-band) are made of actin, while dark bands (A-band) consist of myosin.
Myosin and Actin Interaction
- Myosin filaments are assembled from polymerized proteins called meromyosins, characterized by a globular head (heavy meromyosin) and a tail (light meromyosin).
- The globular head serves as an ATPase enzyme with binding sites for ATP and actin.
- Muscle contraction operates via the sliding filament theory, where thin filaments (actin) slide over thick filaments (myosin).
- Contraction is initiated by signals from the central nervous system (CNS) through motor neurons at the neuromuscular junction.
Rib Structure and Function
- Ribs are thin, flat bones attached posteriorly to the vertebral column and anteriorly to the sternum, featuring two articulation surfaces on their dorsal ends.
- True ribs (first seven pairs) connect directly to the sternum via hyaline cartilage; false ribs (8th, 9th, 10th pairs) connect indirectly while floating ribs (11th and 12th pairs) lack anterior attachment.
- The rib cage is formed by thoracic vertebrae, ribs, and sternum.
Appendicular Skeleton
- Comprises the limbs and girdles, with each limb consisting of 30 bones.
- Forelimb (hand) includes the humerus, radius, ulna, carpals (8), metacarpals (5), and phalanges (14).
- Hind limb (legs) includes the femur (longest bone), tibia, fibula, tarsals (7), metatarsals (5), and phalanges (14).
- Patella (knee cap) is a cup-shaped bone protecting the knee joint.
Girdles and Joint Function
- Pectoral girdle consists of the clavicle and scapula, facilitating upper limb articulation with the axial skeleton.
- Scapula is a triangular bone located between the second and seventh ribs, featuring the acromion for humeral articulation.
- Pelvic girdle is made of two coxal bones formed by the fusion of ilium, ischium, and pubis, including the acetabulum for femur articulation.
Joints and Movement
- Joints enable movement by serving as points of contact between bones or between bones and cartilages, acting as fulcrums for muscle-generated forces.
- Joints are classified as fibrous (no movement, e.g., skull sutures), cartilaginous (limited movement, e.g., vertebrae), and synovial (considerable movement, e.g., knee).
- Examples of synovial joints include ball-and-socket (shoulder), hinge (knee), pivot (between atlas and axis), gliding (carpals), and saddle (thumb).
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