Podcast
Questions and Answers
Which medication works by inhibiting polysynaptic reflexes to reduce muscle spasms and pain?
Which medication works by inhibiting polysynaptic reflexes to reduce muscle spasms and pain?
Which medication is primarily used to treat malignant hyperthermia by preventing muscle contractions?
Which medication is primarily used to treat malignant hyperthermia by preventing muscle contractions?
What is the primary mechanism of action of Botox in muscle paralysis?
What is the primary mechanism of action of Botox in muscle paralysis?
Which of the following is a common side effect associated with Zanaflex?
Which of the following is a common side effect associated with Zanaflex?
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Which medication works by depressing the central nervous system and enhances the effects of GABA,leading to relaxation and sedation?
Which medication works by depressing the central nervous system and enhances the effects of GABA,leading to relaxation and sedation?
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Study Notes
Muscle Spasticity and Related Treatments
- Spasticity: A condition causing muscles to feel stiff and heavy.
- Spasms: Involuntary tightening or contractions of muscles.
- Polysynaptic inhibitors: Medications that work to reduce muscle spasms and pain by influencing polysynaptic reflexes. Examples include Skelaxin, Robaxin, Soma, and Flerexin.
Medications for Muscle Spasticity and Spasms
- Diazepam (Valium): A central nervous system (CNS) depressant, enhancing GABA effects to induce relaxation and sedation. Side effects include drowsiness, dizziness, sedation, weakness, confusion, and risk of dependence.
- Robaxin: Used for acute conditions of the musculoskeletal system.
- Flerexin: Used for short-term relief of muscle spasms and conditions affecting the musculoskeletal system.
- Dantrium: Influences calcium release in the sarcoplasmic reticulum, preventing muscle contraction and used to counter malignant hyperthermia.
- Baclofen (Lioresal): Works in the spinal cord by inhibiting GABA release, reducing excitatory neurotransmitters, decreasing muscle tone.
- Gabapentin: Mechanism of action unknown; used to treat nerve pain. Side effects include edema, fatigue, ataxia, and dizziness or drowsiness.
- Zanaflex: An alpha-2 adrenergic agonist; inhibits neurotransmitter release in the spinal cord, reducing muscle tone. Used for short-term spasticity due to multiple sclerosis (MS) or spinal cord injuries. Side effects include drowsiness, dry mouth, hypotension, weakness, and fatigue.
- Botox: Blocks acetylcholine release, causing muscle paralysis. Side effects include flu-like symptoms, headaches, muscle weakness, and paralysis to non-target muscles.
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Description
Explore the causes and treatments of muscle spasticity and spasms in this quiz. Learn about various medications, including their uses and side effects, to understand how they influence muscle relaxation. Test your knowledge on the pharmacological management of these conditions.
