Muscle Functions Quiz

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Questions and Answers

Which of the following is NOT a function of muscles?

  • Storage of energy (correct)
  • Heat production
  • Protecting bones and internal organs
  • Movement

What characteristic allows muscle cells to respond to stimuli?

  • Excitability (correct)
  • Elasticity
  • Contractility
  • Extensibility

Which connective tissue layer surrounds a muscle fiber?

  • Endomysium (correct)
  • Perimysium
  • Epimysium
  • Sarcoplasm

What are the smallest contractile elements of a muscle unit?

<p>Myofilaments (B)</p> Signup and view all the answers

Which term describes the functional unit of a muscle?

<p>Sarcomere (B)</p> Signup and view all the answers

Which type of muscle is under voluntary control?

<p>Skeletal muscle (A)</p> Signup and view all the answers

How do muscle fascicles contribute to the overall structure of skeletal muscle?

<p>They hold muscle fibers together. (B)</p> Signup and view all the answers

What is the function of the sarcoplasmic reticulum in muscle cells?

<p>Store calcium ions (B)</p> Signup and view all the answers

What is the primary source of ATP in the first 1-2 seconds of muscle contraction?

<p>Creatine phosphate (D)</p> Signup and view all the answers

What process follows the breakdown of glucose into pyruvate during explosive power generation?

<p>Krebs cycle (C)</p> Signup and view all the answers

How does the nervous system increase muscle contraction strength?

<p>By stimulating additional motor units (B)</p> Signup and view all the answers

What characteristic is associated with small motor units?

<p>They enable precise movements. (A)</p> Signup and view all the answers

What happens to muscle tension during repeated stimulation, leading to reduced performance?

<p>Muscle fatigue occurs. (C)</p> Signup and view all the answers

Which factor does NOT affect muscle contraction strength?

<p>The amount of oxygen available (B)</p> Signup and view all the answers

What is the motor unit size dependent on?

<p>The number of muscle fibers it stimulates (D)</p> Signup and view all the answers

What happens to the rate of shortening and relaxation in fatigued muscle?

<p>Both decrease. (B)</p> Signup and view all the answers

What is the primary function of tropomyosin in muscle contraction?

<p>To cover the active binding sites on actin (A)</p> Signup and view all the answers

Which components are essential to form a triad in skeletal muscle?

<p>1 T tubule and 2 Terminal Cisternae (A)</p> Signup and view all the answers

Which protein connects myosin to the Z line and prevents excessive stretching of the sarcomere?

<p>Titin (D)</p> Signup and view all the answers

What role does dystrophin serve in muscle fibers?

<p>Creating intracellular stability (C)</p> Signup and view all the answers

Which type of muscle protein is specifically responsible for linking actin to the Z line?

<p>α-Actinin (D)</p> Signup and view all the answers

The region in a sarcomere that consists solely of thick myofilaments is known as the:

<p>H zone (A)</p> Signup and view all the answers

What occurs when an action potential reaches the triad in skeletal muscle?

<p>Calcium ions flow out of the sarcoplasmic reticulum (B)</p> Signup and view all the answers

What role does calcium play in muscle contraction?

<p>It binds to troponin to initiate contraction. (B)</p> Signup and view all the answers

Which of the following statements about ATP usage in muscle contraction is true?

<p>ATP is required to pump calcium back into the sarcoplasmic reticulum. (D)</p> Signup and view all the answers

What initiates the power stroke during muscle contraction?

<p>The breakdown of ATP into ADP and phosphate. (B)</p> Signup and view all the answers

Which process occurs first during muscle relaxation?

<p>Reuptake of calcium ions by the sarcoplasmic reticulum. (A)</p> Signup and view all the answers

What happens to the tropomyosin during the contraction cycle?

<p>It undergoes a conformational change to expose actin's active sites. (A)</p> Signup and view all the answers

What is the primary function of acetylcholinesterase during muscle contraction?

<p>To degrade acetylcholine in the synaptic cleft. (D)</p> Signup and view all the answers

How does the muscle fiber return to its resting length after contraction?

<p>Through muscle elasticity and cross-bridge separation. (B)</p> Signup and view all the answers

What energy source is utilized immediately before ATP in muscle contraction?

<p>Stored creatine phosphate. (D)</p> Signup and view all the answers

Flashcards

Muscle Excitability

The ability of a muscle cell to respond to stimuli by generating an electrical signal, called an action potential.

Muscle Contractility

The unique ability of muscle cells to shorten and thicken, producing force.

Muscle Extensibility

The capacity of a muscle cell to be stretched without being damaged.

Muscle Elasticity

The ability of a muscle cell to return to its original shape after being stretched.

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Sarcomere: The Functional Unit of Muscle

The smallest contractile unit of a muscle fiber, composed of actin (thin) and myosin (thick) filaments.

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Endomysium

A layer of connective tissue that surrounds a single muscle fiber, providing electrical insulation.

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Perimysium

A layer of connective tissue that surrounds a bundle of muscle fibers (fascicle), helping organize muscles.

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Epimysium

A layer of connective tissue that surrounds the entire skeletal muscle, providing structural support and protection.

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Neuromuscular Junction

A specialized structure formed by the junction of an axon terminal with the motor end plate, responsible for transmitting nerve impulses to muscle fibers.

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Sarcoplasmic Reticulum (SR)

A network of interconnected tubules that surround the myofibrils of a muscle fiber, responsible for storing and releasing calcium ions (Ca+2) during muscle contraction.

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Sarcomere

The functional unit of a muscle fiber, consisting of a repeating sequence of protein filaments that slide past each other during muscle contraction.

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Myosin

A specialized type of protein found within muscles, responsible for converting chemical energy (ATP) into mechanical energy, enabling muscle contraction.

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Actin

A thin protein filament found within muscles, comprised of actin, tropomyosin, and troponin, interacting with myosin to generate contraction.

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Dystroglycan

A protein that binds to both dystrophin and laminin, helping to anchor the cytoskeleton of the muscle fiber to the extracellular matrix.

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Desmin

A protein that plays a crucial role in muscle fiber stability by linking the Z line to the sarcolemma, preventing excessive stretching.

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T-tubules

Specialized invaginations of the sarcolemma, responsible for conducting action potentials from the surface of the muscle fiber towards the sarcoplasmic reticulum.

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Muscle Contraction

The process where muscle fibers shorten, generating force, involving the sliding of actin and myosin filaments past each other.

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Tropomyosin

A protein that covers the active sites of actin filaments in a resting muscle fiber, preventing myosin binding.

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Troponin

A protein complex that binds calcium ions, triggering a conformational change in tropomyosin to expose actin's active sites.

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ATP in Muscle Contraction

The energy source for muscle contraction, providing the energy for myosin head movement and detaching from actin.

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Actomyosin Cross-Bridge Formation

The binding of myosin heads to actin's active sites, forming cross bridges and initiating the power stroke.

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Power Stroke

The event where myosin heads pull actin filaments towards the center of the sarcomere, shortening the muscle fiber.

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Acetylcholinesterase (AChE)

The enzyme that breaks down acetylcholine in the synaptic cleft, stopping muscle contraction.

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SERCA (Sarcoplasmic Reticulum Calcium-ATPase)

A calcium pump located in the sarcoplasmic reticulum (SR) that actively transports calcium ions back into the SR, leading to muscle relaxation.

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ATP stored in muscle fibers

The initial source of energy for muscle contraction, lasting only 1-2 seconds.

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Creatine phosphate

The second energy source for muscle contraction, lasting 8-10 seconds.

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Aerobic Glycolysis

This involves breaking down glucose or glycogen for energy, eventually entering the Kreb's cycle in the mitochondria.

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Recruitment

The central nervous system's way to increase muscle contraction strength by activating more motor units.

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Motor Unit Size

The number of muscle fibers controlled by a single motor neuron.

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Muscle Fatigue

A decrease in muscle force due to repeated stimulation.

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Fast-twitch muscle fibers

Muscle fibers that can contract quickly and forcefully, but fatigue rapidly.

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Slow-twitch muscle fibers

Muscle fibers that contract slowly and fatigue slowly.

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Study Notes

Skeletal Muscle Contraction

  • Skeletal muscles are responsible for movement, posture maintenance, and heat production.
  • Muscles protect bones and internal organs.
  • Key features of muscle cells include excitability (responding to stimuli), contractility (shortening and thickening to generate force), extensibility (extending without damage), and elasticity (returning to original shape).

Muscle Types

  • Skeletal muscle: Fibers are striated, tubular, and multinucleated. Voluntary.
  • Smooth muscle: Fibers are non-striated, spindle-shaped, and uninucleated. Involuntary.
  • Cardiac muscle: Fibers are striated, branched, and uninucleated. Involuntary.

Skeletal Muscle Structure

  • Organization: Actin (thin) and myosin (thick) filaments are the smallest contractile units, forming myofilaments. Myofilaments combine to form myofibrils, which in turn make up muscle fibers. Muscle fibers come together to form fascicles, ultimately creating skeletal muscle.
  • Connective tissue layers: Endomysium (surrounds individual muscle fibers), perimysium (surrounds fascicles), epimysium (surrounds entire muscle).
  • Sarcolemma: The membrane surrounding the muscle fiber,
  • Sarcoplasm: The cytoplasm of the muscle fiber,
  • Sarcoplasmic reticulum (SR): Endoplasmic reticulum of muscle cells, stores calcium.
  • Sarcomere: The functional unit of muscle contraction.
  • I band, A band, Z line, H zone: Regions within the sarcomere.

Neuromuscular Junction

  • The axon terminal of a motor neuron meets the muscle fiber at the motor end plate. This junction is called the neuromuscular junction.
  • Acetylcholine is released at the neuromuscular junction, and it binds to receptors on the muscle fiber, triggering a muscle action potential.
  • Acetylcholinesterase breaks down acetylcholine to stop the signal.

Molecular Mechanisms of Muscle Contraction

  • ATP is crucial for muscle contraction.
  • Myosin heads bind to actin, forming cross-bridges.
  • A power stroke occurs, and the filaments slide past each other.
  • The process repeats as long as calcium and ATP are available.
  • Calcium release is necessary for contraction.

Muscle Relaxation

  • Acetylcholinesterase breaks down acetylcholine.
  • Calcium is reabsorbed by the sarcoplasmic reticulum.
  • Myosin heads detach from actin.
  • The muscle returns to its resting length.

Energy Metabolism during Muscle Contraction

  • Stored ATP is the initial energy source.
  • Creatine phosphate is used to regenerate ATP.
  • Anaerobic glycolysis provides short-term energy.
  • Oxidative phosphorylation provides long-term energy.

Muscle Fatigue

  • Muscle fatigue results from repeated stimulation leading to decreased tension.
  • Factors contributing to fatigue: depletion of ATP, accumulation of metabolic byproducts (lactic acid), and changes in ion concentrations.

Skeletal Muscle Fiber Types

  • Slow-twitch fibers: Endurance activities; high oxidative capacity, lower force production and fatigue rate.
  • Fast-twitch fibers: High-intensity activities; Type 2a (fast oxidative-glycolytic); Type 2x/2b (fast glycolytic); higher force production, fatigue quickly.
  • Different fiber types contribute varying degrees of speed and power. Muscle hypertrophy involves increases in both the size and number of muscle fibers.

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