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Questions and Answers
Which energy system in muscle cells replenishes ATP through oxidative phosphorylation?
Which energy system in muscle cells replenishes ATP through oxidative phosphorylation?
- AMP removal system
- ATP-PC system
- Anaerobic Glycolysis system
- Oxidative system (Aerobic system) (correct)
What is the result of removing 1 phosphate group from ATP?
What is the result of removing 1 phosphate group from ATP?
- AMP
- ADP (correct)
- ADT
- ATPase
During which type of exercise can ATP turnover increase 100-fold above rest?
During which type of exercise can ATP turnover increase 100-fold above rest?
- Sprint exercise (correct)
- Flexibility exercise
- Resistance exercise
- Endurance exercise
What is the primary energy source used to power muscular activity during the initial phase of exercise?
What is the primary energy source used to power muscular activity during the initial phase of exercise?
What is the molecule formed by the removal of 2 phosphate groups from ATP?
What is the molecule formed by the removal of 2 phosphate groups from ATP?
During intense exercise, where does most ATP come from?
During intense exercise, where does most ATP come from?
What is the primary energy source for resting muscle?
What is the primary energy source for resting muscle?
What does the respiratory quotient (RQ) of 0.75 at rest indicate?
What does the respiratory quotient (RQ) of 0.75 at rest indicate?
What is the final product of anaerobic glycolysis?
What is the final product of anaerobic glycolysis?
What are the primary fuels used in muscle metabolism?
What are the primary fuels used in muscle metabolism?
During low-intensity exercise, what is the primary energy source?
During low-intensity exercise, what is the primary energy source?
What is the predominant fuel source during high-intensity activity?
What is the predominant fuel source during high-intensity activity?
What is the main function of lactate in the liver during exercise?
What is the main function of lactate in the liver during exercise?
What contributes to muscle fatigue during exercise?
What contributes to muscle fatigue during exercise?
What is the purpose of the Cori cycle during exercise recovery?
What is the purpose of the Cori cycle during exercise recovery?
During high-intensity activity, which of the following is the most important source of fuel for muscle?
During high-intensity activity, which of the following is the most important source of fuel for muscle?
What is the primary role of liver glycogen during medium-intensity activity?
What is the primary role of liver glycogen during medium-intensity activity?
Which process contributes to the production of glucose from non-glucose sources during exercise?
Which process contributes to the production of glucose from non-glucose sources during exercise?
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Study Notes
- The ATP-PC system is a rapid energy reserve system, using creatine phosphate (CP) to rapidly regenerate ATP for muscle contraction
- ATP is the active energy molecule in the body, and CP is its storage molecule in resting muscle
- The ATP-PC system uses the creatine kinase reaction to maintain ATP concentrations, providing energy for a few seconds
- The synthesis of ATP and CP in the mitochondria are closely coupled
- During intense exercise, most ATP is derived from the breakdown of phosphocreatine (PCr) and glycogen to lactate
- Lactic acid is the final product of anaerobic glycolysis, which favors lactate production in low oxygen conditions
- Lactate accumulates in muscle during intense exercise, causing a drop in pH and diffusing into the bloodstream
- Muscle metabolism primarily uses glucose, glycogen, fatty acids, and ketone bodies as fuels
- The muscle relies on aerobic metabolism of fatty acids in the mitochondria as the primary energy source of the resting muscle, using fatty acids as fuel at rest
- During prolonged exercise, the liver increases the release of glucose into the circulation, and adipose tissue increases the hydrolysis of triglycerides and release of FFAs
- The extent of substrate contribution to ATP production depends on the intensity and duration of muscular activity
- The respiratory quotient (RQ) or respiratory exchange ratio (RER) measures fuel selection by reflecting the substrate being oxidized for energy
- At rest, the RER is 0.75, indicating the body burns approximately 85% fat and 15% carbohydrate
- As exercise intensity increases, the RER also increases to reflect the shift towards carbohydrate oxidation.
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