6 Questions
What causes a conformational change in troponin?
Movement of the entire troponin-tropomyosin complex
During crossbridge cycling, what provides energy to 'cock' the myosin head?
Reset of the myosin head
When myosin heads attach to the exposed binding sites on actin, what is the result?
Tropomyosin is released from the myosin-binding site
What is the result of ADP & Pi release during a power stroke?
Myosin heads bind to actin
What is the consequence of Ca++ & ATP absence during cycling?
Cycling being unable to continue
What toxin leads to spastic paralysis known as tetanus?
Botulinum toxin
Test your knowledge on the muscle contraction mechanism including the role of Ca++, troponin, tropomyosin, crossbridge cycling, and power strokes. Learn about conformational changes in troponin and the steps involved in crossbridge formation.
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