6 Questions
During which step of crossbridge cycling do myosin heads pull thin filaments toward the center of the sarcomere?
Power stroke
In muscle contraction, what causes the release of a myosin head from actin?
ATP binding
Which factor is essential for the continuation of cycling in muscle contraction?
Calcium (Ca++) & ATP
What is the action of Tetanus, caused by toxins from Clostridium tetani?
Blocks the release of inhibitory neurotransmitters
What is the consequence of moving the troponin-tropomyosin complex, exposing the myosin-binding site on actin?
Shortening of the sarcomere
What occurs when ADP & Pi are released during muscle contraction?
ATP is hydrolyzed by myosin ATPase
Test your knowledge on the molecular mechanisms of muscle contraction, including the binding of Ca++ to troponin, conformational changes in troponin, troponin-tropomyosin complex movement, crossbridge cycling steps, crossbridge formation, and power stroke.
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