5 Questions
Was ist der Auslöser für die Kontraktion der Skelettmuskulatur?
Eine Erhöhung der Konzentration von Ca2+
Welche Art von Myosin-Molekülen benötigen eine Aktivierung durch Ca2+-abhängige Phosphorylierung?
Myosin-Moleküle in der glatten Muskulatur
Was bindet an Calmodulin, um Myosin Light Chain Kinase (MLCK) zu aktivieren?
Ca2+
Was phosphoryliert Myosin Light Chain Kinase (MLCK)?
Die regulatorischen leichten Ketten von Myosin (rMLC
Was dephosphoryliert die regulatorischen leichten Ketten von Myosin (rMLC)?
Myosin Light Chain Phosphatase (MLCP
Study Notes
- Skeletal muscle contraction is triggered by an increase in Ca2+ concentration
- Myosin molecules in skeletal muscle are always active
- Myosin molecules in smooth muscle must be activated by Ca2+-dependent phosphorylation
- Ca2+ binds to Calmodulin to activate Myosin Light Chain Kinase (MLCK)
- MLCK phosphorylates the regulatory light chains of myosin (rMLC)
- Phosphorylated rMLC can bind to actin and generate force in the cross-bridge cycle
- ATP is required for both mechanical work and activation mechanism in smooth muscle
- Myosin Light Chain Phosphatase (MLCP) dephosphorylates rMLC
- Smooth muscle stays in an intermediate tension and phosphorylation state
- The balance between MLCK and MLCP activity determines muscle tone.
Test your knowledge on the fascinating world of muscle contraction with this quiz! From the role of calcium ions to the importance of ATP, this quiz covers the fundamental mechanisms of skeletal and smooth muscle contraction. Take the quiz to learn about the key players involved in generating force in the cross-bridge cycle and how the balance between MLCK and MLCP activity determines muscle tone. Perfect for students of biology, anatomy or physiology, this quiz will help you master the complexities of muscle contraction.
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