Podcast
Questions and Answers
Which type of calcium channels are responsible for the influx of extracellular calcium in smooth muscle contraction?
Which type of calcium channels are responsible for the influx of extracellular calcium in smooth muscle contraction?
- Ryanodine receptors (RYRs)
- Dihydropyridine receptors (DHPR) (correct)
- L-type calcium channels
- Calcium-gated calcium channels
What is the main role of ryanodine receptors (RYRs) in smooth muscle contraction?
What is the main role of ryanodine receptors (RYRs) in smooth muscle contraction?
- Bind dihydropyridine class drugs
- Release calcium from the sarcoplasmic reticulum (SR) (correct)
- Release calcium from the cytosol
- Mediate calcium entry during the action potential
Which source of calcium has a higher concentration in the cytosol and requires the entry of trigger calcium for its release?
Which source of calcium has a higher concentration in the cytosol and requires the entry of trigger calcium for its release?
- Calcium released from the sarcoplasmic reticulum (SR) (correct)
- Calcium-gated calcium channels
- Dihydropyridine receptors (DHPR)
- Extracellular calcium
Which event of excitation-contraction coupling in smooth muscle leads to the exposure of myosin binding sites on actin?
Which event of excitation-contraction coupling in smooth muscle leads to the exposure of myosin binding sites on actin?
What is the role of the Ca2+-ATPase pump (SERCA1 and SERCA2) in smooth muscle relaxation?
What is the role of the Ca2+-ATPase pump (SERCA1 and SERCA2) in smooth muscle relaxation?
How is calcium returned to the extracellular area in smooth muscle?
How is calcium returned to the extracellular area in smooth muscle?
Which factor can increase the force of contraction in smooth muscle?
Which factor can increase the force of contraction in smooth muscle?
What is positive lusitropy in smooth muscle?
What is positive lusitropy in smooth muscle?
What type of smooth muscle contraction is sustained at a low energy expenditure?
What type of smooth muscle contraction is sustained at a low energy expenditure?
Which of the following is a unique biophysical property of smooth muscle?
Which of the following is a unique biophysical property of smooth muscle?
What is aganglionic megacolon or Hirschsprung's disease characterized by?
What is aganglionic megacolon or Hirschsprung's disease characterized by?
Why is the load-velocity relationship slower in smooth muscle?
Why is the load-velocity relationship slower in smooth muscle?
