Podcast
Questions and Answers
Which protein is involved in calcium-induced calcium release in cardiac muscle?
Which protein is involved in calcium-induced calcium release in cardiac muscle?
- Troponin-C (correct)
- Myosin
- Actin
- Tropomyosin
What is the role of the sodium-calcium exchanger in cardiac muscle?
What is the role of the sodium-calcium exchanger in cardiac muscle?
- To pump sodium ions out of the sarcoplasmic reticulum
- To pump calcium ions out of the sarcoplasmic reticulum (correct)
- To pump calcium ions into the sarcoplasmic reticulum
- To pump sodium ions into the sarcoplasmic reticulum
What is the relationship between intracellular free calcium concentration and force generation by cardiac muscle?
What is the relationship between intracellular free calcium concentration and force generation by cardiac muscle?
- Force generation is independent of intracellular free calcium concentration
- As intracellular free calcium concentration increases, force generation increases (correct)
- Intracellular free calcium concentration does not affect force generation
- As intracellular free calcium concentration increases, force generation decreases
Which of the following is responsible for the strength of contraction of each myocardial cell?
Which of the following is responsible for the strength of contraction of each myocardial cell?
What is the main role of the T-tubular system in cardiac muscle?
What is the main role of the T-tubular system in cardiac muscle?
What is the function of the sarcoplasmic reticulum in excitation-contraction coupling?
What is the function of the sarcoplasmic reticulum in excitation-contraction coupling?
How does Ca2+ induce muscle contraction in cardiac muscle?
How does Ca2+ induce muscle contraction in cardiac muscle?
Which of the following is NOT a mechanism that impacts contractility in the heart?
Which of the following is NOT a mechanism that impacts contractility in the heart?
What is the effect of heart rate on contractility in the heart?
What is the effect of heart rate on contractility in the heart?
Can cardiac muscle be tetanized?
Can cardiac muscle be tetanized?
How do defects in the sarcoplasmic reticulum Ca pump (SERCA) affect contractility in the heart?
How do defects in the sarcoplasmic reticulum Ca pump (SERCA) affect contractility in the heart?
Which mechanism actively transports Ca2+ out of the cell by exchanging 3 Na+ for 1 Ca2+?
Which mechanism actively transports Ca2+ out of the cell by exchanging 3 Na+ for 1 Ca2+?
Which mechanism actively transports Ca2+ back into the sarcoplasmic reticulum (SR) by using ATP?
Which mechanism actively transports Ca2+ back into the sarcoplasmic reticulum (SR) by using ATP?
What is the term for the intrinsic ability of cardiac muscle to develop force at a given muscle length?
What is the term for the intrinsic ability of cardiac muscle to develop force at a given muscle length?
Which mechanism increases the force of cardiac contractility by increasing the rate and magnitude of Ca2+ release from the sarcoplasmic reticulum (SR)?
Which mechanism increases the force of cardiac contractility by increasing the rate and magnitude of Ca2+ release from the sarcoplasmic reticulum (SR)?