16 Questions
What is the most common primary bone tumor?
Multiple myeloma
What percentage of multiple myeloma patients are older than 40 years of age?
95%
What is the characteristic radiographic feature of plasmacytoma?
Lytic expansile geographic lesions with a narrow zone of transition
What is the distribution of plasmacytoma occurrence in the skeleton?
Distribution follows the red (hematopoietic) marrow in the skeleton
What is the differential diagnosis of plasmacytoma based on?
Radiographic appearance
What is the characteristic size of lytic lesions in multiple myeloma?
Generally smaller than 1 cm
What percentage of multiple myeloma cases are associated with symptomatic amyloidosis?
10-15%
What is the term for the syndrome associated with sclerotic patterns in multiple myeloma?
POEMS syndrome
What is the primary role of imaging in multiple myeloma detection and staging?
To assess the overall tumor burden
What is the most accurate test for assessing disease response and posttreatment surveillance in multiple myeloma?
FDG PET-CT
What is the significance of a variegated pattern on MRI in multiple myeloma?
It suggests diffuse marrow infiltration
What is the primary difference between multiple myeloma and metastatic disease?
Pattern of bone marrow infiltration
What is the prognosis for patients with multiple myeloma who have a high tumor burden and elevated serum tumor markers?
Poor prognosis
What is the primary treatment for patients with multiple myeloma who have spinal cord compression?
Radiation therapy
What is the significance of unexplained generalized osteopenia in a middle-aged patient?
It may suggest multiple myeloma
What is the current 5-year survival rate for patients with multiple myeloma in the US?
>50%
Test your knowledge of multiple myeloma, a type of cancer that affects plasma cells. This quiz covers the common appearance, symptoms, and characteristics of multiple myeloma, including punched-out lytic lesions and osteopenia. Assess your understanding of this primary bone tumor.
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