Mucocutaneous Leishmaniasis: Lesions and Epidemiology

Shaded stream banks

Tropical west and central Africa

Cardiac muscle

<p>South and Central America</p> Signup and view all the answers

<p>Cutaneous leishmaniasis, Visceral leishmaniasis, Mucocutaneous leishmaniasis</p> Signup and view all the answers

<p>Amastigote (aflagellar) and Promastigote (flagellated)</p> Signup and view all the answers

<p>Liver, Spleen, Bone marrow</p> Signup and view all the answers

<p>Reticuloendothelial system of the viscera</p> Signup and view all the answers

<p>Tse tse fly</p> Signup and view all the answers

<p>An elongated spindle-shaped body that tapers at both ends, a centrally situated nucleus, a kinetoplast posterior to nucleus, an undulating membrane arising from the kinetoplast, and a single free flagellum at the anterior end.</p> Signup and view all the answers

<p>Demonstration of the amastigotes in properly stained smears from touch preparations of ulcer biopsy specimen.</p> Signup and view all the answers

<p>Typical somnolence (sleepiness) progresses to coma as a result of demyelinating encephalitis.</p> Signup and view all the answers

<p>Endothelial cells of the capillaries, nearby lymph nodes, within large mononuclear cells, in neutrophilic leukocytes, and free in the serum exuding from the ulcerative site.</p> Signup and view all the answers

<p>Lesions are confined to the skin in cutaneous leishmaniasis and to the mucous membranes, cartilage, and skin in mucocutaneous leishmaniasis. A granulomatous response occurs, and a necrotic ulcer forms at the bite site.</p> Signup and view all the answers

<p>Many parts of Asia, Africa, Mediterranean Europe, and the southern region of the former Soviet Union.</p> Signup and view all the answers

<p>The lesions tend to become superinfected with bacteria, and secondary lesions occur on the skin as well as in mucous membranes.</p> Signup and view all the answers

<p>Amastigote (aflagellar) and promastigote (flagellated)</p> Signup and view all the answers

<p>Liver, spleen, and bone marrow</p> Signup and view all the answers

<p>Reticuloendothelial system of the viscera</p> Signup and view all the answers

<p>Kala-azar ('black sickness')</p> Signup and view all the answers

<p>Polypoid</p> Signup and view all the answers

<p>Demonstration of the amastigotes in properly stained smears</p> Signup and view all the answers

<p>Tse tse fly</p> Signup and view all the answers

<p>Somnolence progressing to coma</p> Signup and view all the answers

<p>Endothelial cells of the capillaries of the infected site, nearby lymph nodes, within large mononuclear cells, in neutrophilic leukocytes, and free in the serum exuding from the ulcerative site.</p> Signup and view all the answers

<p>The introduced parasites round up to form amastigote and multiply.</p> Signup and view all the answers

<p>Mucous membranes, cartilage, and skin.</p> Signup and view all the answers

<p>Many parts of Asia, Africa, Mediterranean Europe, and the southern region of the former Soviet Union.</p> Signup and view all the answers

<p>Shaded stream banks</p> Signup and view all the answers

<p>Cardiac muscle</p> Signup and view all the answers

<p>South and Central America</p> Signup and view all the answers

<p>Triatomid bug</p> Signup and view all the answers

<p>Nonpathogenic, larger than histolytica, contains ingested bacteria but no red cells, visible nucleus with large eccentric karyosome.</p> Signup and view all the answers

<p>Small trophozoite size, inconspicuous or absent chromidial bars in cyst, nonpathogenic.</p> Signup and view all the answers

<p>Small trophozoite size, prominent nucleus with bull's eye appearance, widely distributed.</p> Signup and view all the answers

<p>Entamoeba coli is larger, contains ingested bacteria but no red cells, while Endolimax nana has a small size and inconspicuous chromidial bars.</p> Signup and view all the answers

<p>Shaded stream banks</p> Signup and view all the answers

<p>South and Central America</p> Signup and view all the answers

<p>Cardiac muscle</p> Signup and view all the answers

<p>Centrifugation of heparinized samples and ion-exchange chromatography</p> Signup and view all the answers

<p>Endothelial cells of the capillaries of the infected site, nearby lymph nodes, within large mononuclear cells, in neutrophilic leukocytes, and free in the serum exuding from the ulcerative site.</p> Signup and view all the answers

<p>Mucocutaneous leishmaniasis is the same as oriental sore, but some strains tend to invade the mucous membranes of the mouth, nose, pharynx, and larynx.</p> Signup and view all the answers

<p>The lesions are confined to the skin in cutaneous leishmaniasis and to the mucous membranes, cartilage, and skin in mucocutaneous leishmaniasis. A granulomatous response occurs, and a necrotic ulcer forms at the bite site.</p> Signup and view all the answers

<p>Cutaneous leishmaniasis produced by L. tropica complex is present in many parts of Asia, Africa, Mediterranean Europe, and the southern region of the former Soviet Union.</p> Signup and view all the answers

<p>Tse tse fly</p> Signup and view all the answers

<p>Demonstration of amastigotes in properly stained smears from touch preparations of ulcer biopsy specimen.</p> Signup and view all the answers

<p>An elongated spindleshaped body that tapers at both ends, a centrally situated nucleus, a kinetoplast posterior to nucleus, an undulating membrane, and a single free flagellum.</p> Signup and view all the answers

<p>Trypomastigotes spread from the skin through the blood to the lymph node and brain, leading to somnolence progressing to coma due to demyelinating encephalitis.</p> Signup and view all the answers