MT 38 Lab - Dengue NS1 Antigen Testing

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18 Questions

What is considered Dengue without warning signs according to the W.H.O classification?

Fever with positive tourniquet test

Which vector is more common in transmitting Dengue Fever?

Aedes aegypti

What is a characteristic feature of Dengue Shock Syndrome (DSS)?

Bleeding tendencies

Which of the following is NOT one of the warning signs of severe Dengue according to W.H.O classification?

Positive tourniquet test

What is the most common method for detecting Dengue Virus antigen?

Enzyme-linked immunosorbent assay (ELISA)

How many petechiae per square inch are considered positive for the tourniquet test?

10 or more

What is a common clinical fluid accumulation observed in Dengue with warning signs?

Ascites

Which of the following is not a symptom associated with Dengue with warning signs?

Muscle pain

What is a characteristic of Severe Dengue according to the W.H.O classification?

Impaired consciousness

What method can be used to detect Dengue Virus antigens in tissue?

Immunofluorescence assay

Which body fluid can be used for detecting DENV nucleic acid according to the text?

Cerebrospinal fluid (CSF)

IgM/IgG anti-DENV can be detected by immunoassay. Which of the following body fluids can this detection be conducted on?

Serum or CSF

Which phase of dengue virus infections is NS1 detectable according to the text?

During the acute phase

What does a negative NS1 test result indicate?

No current infection

What should be done if someone tests negative for NS1 but suspects a recent dengue exposure?

Check for dengue IgM antibodies

What does a positive result on the NS1 test confirm?

The presence of a recent dengue infection

What does the text suggest about second-time dengue infections?

They are more severe due to the same serotype exposure

What is the principle behind the Abbott Dengue Duo Test Kit according to the text?

Immunochromatography /Lateral Flow Immunoassay

This quiz covers the basics of NS1 tests for dengue virus, which detect the non-structural protein NS1 secreted in the blood during infection. Learn about the sensitivity of NS1 tests during the acute phase of dengue infections and their recommended usage within the first 7 days of symptoms.

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