Questions and Answers
Who first described phagocytosis?
Metchnikoff
Chronic granulomatous disease represents a defect of:
Oxidative metabolism
Jenner's work with cowpox demonstrated which phenomenon?
Cross-immunity
Which event is not associated with some aspect of neutrophil function?
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Which cells destroy tumor cells using ADCC as a recognition mode and perforin as an effector molecule?
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Study Notes
Immunology Basics
- Phagocytosis was first described by Elie Metchnikoff.
Immune Deficiencies
- Chronic granulomatous disease is characterized by a defect in the oxidative killing mechanism of phagocytic cells.
Vaccine Development
- Edward Jenner's work with cowpox demonstrated the concept of cross-protection.
Neutrophil Function
- The formation of granulomas is not associated with neutrophil function.
Immune Cell Function
- Natural killer cells destroy tumor cells using antibody-dependent cellular cytotoxicity (ADCC) as a recognition mode and perforin as an effector molecule.
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