MSOP1016: Science of Medicines 3 Antibacterial Agents & Antimicrobial Resistance
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Questions and Answers

What is the main topic discussed in the provided resources?

  • The history of antibacterial agents
  • The comparison between antibiotics and oncology drugs
  • The effectiveness of different antibiotics in clinical development
  • The current state and future of antimicrobial resistance (correct)

    • Which of the following is NOT a resource about the antibiotic pipeline?

  • <a href="https://www.optum.com/business/resources/library/oncology-drugs.html">https://www.optum.com/business/resources/library/oncology-drugs.html</a> (correct)
  • <a href="https://antibiotics-theperfectstorm.blogspot.co.uk/2018/01/">https://antibiotics-theperfectstorm.blogspot.co.uk/2018/01/</a>
  • <a href="https://twitter.com/sidpharm/status/1179080556631322626">https://twitter.com/sidpharm/status/1179080556631322626</a>
  • <a href="https://www.imi.europa.eu/projects-results/project-factsheets/nd4bb">https://www.imi.europa.eu/projects-results/project-factsheets/nd4bb</a>

    • Which of the following is an ongoing initiative to combat antimicrobial resistance?

  • World Health Organization
  • Carb-X
  • European Union's Innovative Medicines Initiative
  • All of the above (correct)

    • According to the World Health Organization report, how many antibacterial agents were in clinical development in 2019?

    <p>Not mentioned in the provided resources</p> Signup and view all the answers

    Which path is suggested to be taken in the context of 'new' antibiotics?

    <p>The text does not suggest a specific path</p> Signup and view all the answers

    What is the focus of the text in relation to antibiotic development?

    <p>Developing novel chemical classes of antibiotics</p> Signup and view all the answers

    Which characteristic best measures the level of innovation in a new antibiotic?

    <p>Absence of cross-resistance to existing antibiotics</p> Signup and view all the answers

    Which of the following is NOT mentioned as an example of a new target for antibiotic development?

    <p>Elongation factors</p> Signup and view all the answers

    What is the mechanism of action of Afabicin in bacterial cells?

    <p>Interferes with fatty acid biosynthesis</p> Signup and view all the answers

    Which antibiotic is specifically mentioned for its activity against Pseudomonas aeruginosa but faced concerns about nephrotoxicity?

    <p>Murepavadin</p> Signup and view all the answers

    Which antibiotic was recently approved for the treatment of community-acquired bacterial pneumonia?

    <p>Pretomanid</p> Signup and view all the answers

    What role do antibiotic adjuvants play?

    <p>Increase the potency of antibiotics</p> Signup and view all the answers

    'MoA' in 'Pleuromutilins - MoA' stands for:

    <p>Mode of Action</p> Signup and view all the answers

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