MSOP1016: Science of Medicines 3 Antibacterial Agents & Antimicrobial Resistance

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Questions and Answers

What is the main topic discussed in the provided resources?

  • The history of antibacterial agents
  • The comparison between antibiotics and oncology drugs
  • The effectiveness of different antibiotics in clinical development
  • The current state and future of antimicrobial resistance (correct)

Which of the following is NOT a resource about the antibiotic pipeline?

  • <a href="https://www.optum.com/business/resources/library/oncology-drugs.html">https://www.optum.com/business/resources/library/oncology-drugs.html</a> (correct)
  • <a href="https://antibiotics-theperfectstorm.blogspot.co.uk/2018/01/">https://antibiotics-theperfectstorm.blogspot.co.uk/2018/01/</a>
  • <a href="https://twitter.com/sidpharm/status/1179080556631322626">https://twitter.com/sidpharm/status/1179080556631322626</a>
  • <a href="https://www.imi.europa.eu/projects-results/project-factsheets/nd4bb">https://www.imi.europa.eu/projects-results/project-factsheets/nd4bb</a>

Which of the following is an ongoing initiative to combat antimicrobial resistance?

  • World Health Organization
  • Carb-X
  • European Union's Innovative Medicines Initiative
  • All of the above (correct)

According to the World Health Organization report, how many antibacterial agents were in clinical development in 2019?

<p>Not mentioned in the provided resources (D)</p> Signup and view all the answers

Which path is suggested to be taken in the context of 'new' antibiotics?

<p>The text does not suggest a specific path (B)</p> Signup and view all the answers

What is the focus of the text in relation to antibiotic development?

<p>Developing novel chemical classes of antibiotics (B)</p> Signup and view all the answers

Which characteristic best measures the level of innovation in a new antibiotic?

<p>Absence of cross-resistance to existing antibiotics (C)</p> Signup and view all the answers

Which of the following is NOT mentioned as an example of a new target for antibiotic development?

<p>Elongation factors (D)</p> Signup and view all the answers

What is the mechanism of action of Afabicin in bacterial cells?

<p>Interferes with fatty acid biosynthesis (B)</p> Signup and view all the answers

Which antibiotic is specifically mentioned for its activity against Pseudomonas aeruginosa but faced concerns about nephrotoxicity?

<p>Murepavadin (B)</p> Signup and view all the answers

Which antibiotic was recently approved for the treatment of community-acquired bacterial pneumonia?

<p>Pretomanid (B)</p> Signup and view all the answers

What role do antibiotic adjuvants play?

<p>Increase the potency of antibiotics (B)</p> Signup and view all the answers

'MoA' in 'Pleuromutilins - MoA' stands for:

<p>Mode of Action (B)</p> Signup and view all the answers

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