MRI T1 and T2 Curves

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Questions and Answers

How does increasing the external magnetic field strength typically affect the T1 relaxation time of a tissue?

  • It shortens the T1 relaxation time.
  • It lengthens the T1 relaxation time. (correct)
  • It initially shortens and then lengthens the T1 relaxation time.
  • It does not affect the T1 relaxation time.

What percentage of its maximum value does the transverse magnetization (TM) reduce to during T2 relaxation?

  • Approximately 13%
  • Approximately 37% (correct)
  • Approximately 50%
  • Approximately 63%

What is the primary factor that T2 relaxation depends on within tissues?

  • Strength of the applied radiofrequency pulse.
  • Inhomogeneity of local magnetic fields. (correct)
  • Temperature of the tissue.
  • Homogeneity of external magnetic fields.

Why do water molecules typically exhibit a longer T2 relaxation time compared to tissues with larger molecules?

<p>Water molecules move very fast, causing magnetic fields to cancel each other out. (D)</p> Signup and view all the answers

What characteristic of impure liquids or tissues with larger molecules leads to a shorter T2 relaxation time?

<p>Decreased molecular motion. (A)</p> Signup and view all the answers

Which of the following statements accurately describes the T2* (T2 star) relaxation time?

<p>T2* is less than T2 due to the influence of external magnetic field inhomogeneities. (D)</p> Signup and view all the answers

How does the motion of molecules within a tissue affect T2 relaxation?

<p>Faster molecular motion leads to longer T2 relaxation due to decreased magnetic field inhomogeneity. (D)</p> Signup and view all the answers

A researcher observes that a particular tissue sample exhibits a short T2 relaxation time. Which of the following could explain this observation?

<p>The tissue contains a high concentration of large molecules or impurities. (B)</p> Signup and view all the answers

In gradient echo sequences, why is T2* relaxation time typically shorter than T2 relaxation time?

<p>Because gradient echo sequences are sensitive to both intrinsic and extrinsic magnetic field inhomogeneities. (A)</p> Signup and view all the answers

If a tissue has a high degree of local magnetic field homogeneity, how will this affect its T2 relaxation time?

<p>The T2 relaxation time will be longer because protons stay in phase longer. (B)</p> Signup and view all the answers

Flashcards

What is T2 relaxation time?

Time taken for transverse magnetization (TM) to disappear or decay to 37% of its maximum value.

What causes T2 relaxation?

Caused by the inhomogeneity of local magnetic fields within tissues.

Why does water have a long T2?

Water molecules move fast, their magnetic fields fluctuate rapidly, canceling each other out, leading to a longer T2.

Why do impure liquids have short T2?

Impure liquids or tissues with large molecules move slowly, maintaining inhomogeneity, causing rapid dephasing and a short T2.

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Does fat have shorter or longer T2?

Fat has a shorter T2 relaxation time compared to water in MRI.

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What is T2* (T2 star) relaxation?

In addition to tissue inhomogeneities, external magnetic field (B0) inhomogeneity also causes decay of transverse magnetization (TM).

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How is T1 relaxation affected by magnetic field strength?

T1 increases with higher magnetic field strength; it's longer, for example, at 3T compared to 1.5T.

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Study Notes

  • Impure liquids or tissues with larger molecules move at a slow rate and have short T2
  • Fat has shorter T2
  • Liquids maintain homogeneity
  • Protons stay in phase for a long time resulting in long T2

T1 and T2 Curves

  • T1 increases with the strength of the external magnetic field
  • T1 at 3T is longer than T1 of the same tissue at 1.5T

T2

  • T2 is the time taken by transverse magnetization (TM) to disappear
  • Similar to T1, it is considered a 'constant' but not an exact time
  • T2 is the time taken for TM to reduce to 37% of its maximum value.
  • The T2 curve shows the decrease in magnitude (decay) of the TM plotted against time
  • 1/T2 is the transverse relaxation rate
  • T2 depends on the inhomogeneity of local magnetic fields within the tissues
  • Water molecules move very fast, and their magnetic fields fluctuate fast canceling the magnetic fields
  • Due to lack of inhomogeneity, protons stay in phase resulting in long T2 for water
  • Impure liquid or tissue with larger molecules move slower, maintaining inhomogeneity; protons go out of phase fast, with short T2

T2* (T2 star)

  • T2* is relevant in Gradient Recalled Echo (GRE) sequences
  • T2* is less than T2
  • In addition to magnetic field inhomogeneity intrinsic to tissues causing spin-spin relaxation, inhomogeneity of the external magnetic field (B0) also causes decay of transverse magnetization (TM).

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