MRI Image Processing Fundamentals

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Questions and Answers

What determines a T1-weighted image?

  • Repetition Time (TR) (correct)
  • Time to Echo (TE)
  • Length of RF pulses
  • Signal decay rate

A longer TR allows for better differentiation between tissues in T1-weighted imaging.

False (B)

What is the time between the delivery of the RF pulse and the receipt of the echo signal called?

Time to Echo (TE)

If TR is ____, tissue A and B cannot be differentiated due to equal longitudinal magnetization.

<p>long</p> Signup and view all the answers

Match the following terms with their definitions:

<p>TR = The time between successive RF pulse sequences applied TE = The duration from RF pulse delivery to echo signal receipt T1-weighted imaging = Determines tissue contrast based on longitudinal relaxation T2-weighted imaging = Focuses on transversal relaxation differences</p> Signup and view all the answers

What is one way to alter the slice thickness during imaging?

<p>By changing the band width of the RF pulse (D)</p> Signup and view all the answers

The frequency encoding gradient is applied along the x-axis.

<p>False (B)</p> Signup and view all the answers

What is the main purpose of the slice selection gradient?

<p>To excite the protons in the specific slice intended for imaging.</p> Signup and view all the answers

What effect does a 180-degree pulse have on protons during a Spin Echo sequence?

<p>Protons change direction and become in phase. (C)</p> Signup and view all the answers

A longer TE results in a stronger spin echo signal.

<p>False (B)</p> Signup and view all the answers

To increase image resolution, one can use a ______ slice, given there are enough protons.

<p>thinner</p> Signup and view all the answers

Match the following gradients with their functionality:

<p>Slice selection gradient = Excites specific slice of protons Frequency encoding gradient = Applies different precession frequencies along y-axis Phase encoding gradient = Creates varying frequencies along x-axis Gradient field = Modifies strength of the magnetic field</p> Signup and view all the answers

What is the purpose of a 90-degree RF pulse in Spin Echo sequences?

<p>To initiate transverse magnetization by tipping protons into the transverse plane.</p> Signup and view all the answers

What happens if the slice is too thin?

<p>There is not enough signal due to insufficient protons. (D)</p> Signup and view all the answers

Protons in ________ dephase slower than protons in fatty tissue, resulting in a stronger signal.

<p>fluid</p> Signup and view all the answers

Match the TE conditions to their corresponding image quality:

<p>Short TE = Weaker overall signal Long TE = Stronger spin echo signal Short TR, Short TE = T1-weighted image Long TR, Long TE = T2-weighted image</p> Signup and view all the answers

The phase encoding gradient is activated after the slice selection gradient.

<p>True (A)</p> Signup and view all the answers

What is the result of applying multiple 180-degree pulses in a Spin Echo sequence?

<p>The signal intensity gradually decreases. (C)</p> Signup and view all the answers

What factor can help to obtain a thicker slice when employing a gradient field?

<p>Using a wider band width of the RF pulse.</p> Signup and view all the answers

T2-curve is a representation of signal intensity over time in an MRI.

<p>True (A)</p> Signup and view all the answers

What happens if no 180-degree pulse is applied during the imaging process?

<p>The signal decays faster, producing a T2*-curve.</p> Signup and view all the answers

Flashcards

Repetition Time (TR)

The time between successive RF pulses applied to the same slice.

Time to Echo (TE)

The time between the delivery of the RF pulse and the reception of the echo signal.

T1-weighted image

An MRI image where signal intensity is primarily determined by the rate at which tissues regain their magnetization after a pulse (T1).

T1-weighted image interpretation

Tissue A has a shorter T1 relaxation time than tissue B. Signal intensity is stronger for tissue A.

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Short TR vs. Long TR

A short TR (time between pulses) allows tissue A to regain more magnetization compared to tissue B, resulting in a stronger signal for tissue A.

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TE/2

The time between the 90 degree pulse and the 180 degree pulse in a spin echo sequence.

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TE (Time to Echo)

The time between the initial 90 degree pulse and the echo signal in a spin echo sequence.

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Spin Echo Sequence

A sequence that uses one 90 degree pulse and at least one 180 degree pulse to generate an echo signal.

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Dephasing

The process where protons in a magnetic field lose their alignment and return to their original state after a 90 degree pulse.

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T2*

The time constant that describes the rate at which the protons lose their alignment after a 90 degree pulse due to the magnetic field inhomogeneities.

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T2

The time constant that describes the rate at which the protons lose their alignment after a 90 degree pulse due to interactions between the protons.

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Signal Strength

The signal intensity of an image is determined by the strength of the transverse magnetization.

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Contrast

The ability of an imaging technique to differentiate between different tissues based on their characteristics.

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Slice Selection

A process that is used to select a specific slice of tissue within the body for imaging.

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Slice Selection Gradient

A magnetic field gradient that is used to select a specific slice of tissue by assigning different frequencies to protons based on their position along the gradient.

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Slice Thickness: Frequency Bandwidth

The thickness of the slice that is being imaged can be controlled by altering the range of frequencies used in the slice selection gradient.

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Slice Thickness: Gradient Steepness

The thickness of the slice can also be adjusted by changing the steepness of the magnetic field gradient; a steeper gradient means more variation in precession frequencies, leading to thinner slices.

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Frequency Encoding Gradient

A magnetic field gradient applied in the y-axis after slice selection to differentiate protons along that axis based on their precession frequencies. This allows for distinguishing signals originating from different columns in the final image.

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Phase Encoding Gradient

A magnetic field gradient applied in the x-axis after the RF pulse. It causes protons along the x-axis to precess at different frequencies, resulting in phase shifts in the signals. This allows for distinguishing the signals from different rows in the final image.

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Image Reconstruction from Signals

The process of using the signals from different frequencies and phases to reconstruct an image. Each signal corresponds to a specific spatial location within the slice.

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Tissue Contrast Based on Properties

The ability to distinguish between different types of tissues depends on their unique properties. Properties such as T1 and T2 relaxation times influence the signal intensity of a tissue and can be manipulated to highlight specific structures in the image.

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Study Notes

Patient Signal Processing in MRI

  • MRI uses pulse sequences to differentiate tissues
  • Image creation varies with RF pulse sequences
  • Repetition Time (TR) is the time between RF pulses for a slice
  • Time to Echo (TE) is the time between RF pulse and echo signal receipt

Tissue Differentiation

  • Different tissues have different relaxation times

  • Short TR—shows T1 weighted image

  • Long TR—shows T2 weighted image

  • Short TE— stronger spin echo signal of tissue A compared to tissue B, good for differentiating between the two tissues

  • Long TE— weaker spin echo signal, harder to differentiate tissues visually

Spin Echo Sequences

  • Consist of a 90° RF pulse and at least one 180° pulse
  • Longitudinal magnetization increases after the 90° pulse, then dephased
  • 180° pulse reverses the dephasing of protons , leading to a spin echo signal
  • Signal strength depends on T2 properties of tissue
  • T2 signal decreases with time
  • Short TE results in stronger signal
  • Long TE results in weaker signal, harder to distinguish tissues

Slice Selection

  • Using gradients in the magnetic field to select a specific slice for imaging
  • Slice thickness altered by RF pulse band width or gradient steepness
  • Thinner slices require higher magnetic field strength for better resolution

Signal Location for Image Reconstruction

  • Frequency encoding gradient applied in the y-direction; creates varied precession frequencies

  • Phase encoding gradient applied in the x-direction; temporal variations in precession frequency

  • Spatial locations determined by frequency and phase of signals

  • Fourier transformation analyzes the combined signal information to map location and intensity of voxels in an image

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