Podcast
Questions and Answers
Which of the following does not fall under the operator's control in MRI?
Which of the following does not fall under the operator's control in MRI?
What does the Apparent Diffusion Coefficient (ADC) measure?
What does the Apparent Diffusion Coefficient (ADC) measure?
What is meant by dephasing in MRI?
What is meant by dephasing in MRI?
What is the purpose of excitation in MRI?
What is the purpose of excitation in MRI?
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What is an electromagnet?
What is an electromagnet?
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What does precessional phase refer to when magnetic moments of hydrogen are involved?
What does precessional phase refer to when magnetic moments of hydrogen are involved?
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Which statement best describes resonance in the context of MRI?
Which statement best describes resonance in the context of MRI?
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What happens to the NMV when the RF excitation pulse is switched off?
What happens to the NMV when the RF excitation pulse is switched off?
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What is the process called when hydrogen nuclei lose energy after the RF pulse is turned off?
What is the process called when hydrogen nuclei lose energy after the RF pulse is turned off?
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What does dephasing in MRI indicate?
What does dephasing in MRI indicate?
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What is the role of Faraday's law in MRI?
What is the role of Faraday's law in MRI?
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What occurs simultaneously with the relaxation of hydrogen nuclei?
What occurs simultaneously with the relaxation of hydrogen nuclei?
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What is the result of hydrogen nuclei being exposed to an RF pulse?
What is the result of hydrogen nuclei being exposed to an RF pulse?
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What is the term for the signal that decays due to the transverse coherent magnetization decreasing?
What is the term for the signal that decays due to the transverse coherent magnetization decreasing?
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What does the TR parameter determine in the context of RF excitation pulses?
What does the TR parameter determine in the context of RF excitation pulses?
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How is the TE parameter defined?
How is the TE parameter defined?
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Which of the following is NOT considered an extrinsic contrast parameter?
Which of the following is NOT considered an extrinsic contrast parameter?
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What does increasing the flip angle do in an imaging scenario?
What does increasing the flip angle do in an imaging scenario?
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Which parameter reflects the timing of gradients used to create diffusion-weighted images?
Which parameter reflects the timing of gradients used to create diffusion-weighted images?
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What effect does the TE parameter have on T2 relaxation when reading the signal?
What effect does the TE parameter have on T2 relaxation when reading the signal?
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In what unit is the TR measurement expressed?
In what unit is the TR measurement expressed?
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What occurs when the magnetic moments of hydrogen gain energy from an external source?
What occurs when the magnetic moments of hydrogen gain energy from an external source?
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What phenomenon results from the magnetic moments of hydrogen aligning with each other after being affected by resonance?
What phenomenon results from the magnetic moments of hydrogen aligning with each other after being affected by resonance?
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During the free induction decay (FID) signal, what primarily influences the net magnetization vector (NMV) after the RF excitation pulse is turned off?
During the free induction decay (FID) signal, what primarily influences the net magnetization vector (NMV) after the RF excitation pulse is turned off?
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What process describes the return of high-energy hydrogen nuclei to a low-energy population after the RF pulse is shut off?
What process describes the return of high-energy hydrogen nuclei to a low-energy population after the RF pulse is shut off?
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What leads to the dephasing of magnetic moments in hydrogen after RF excitation?
What leads to the dephasing of magnetic moments in hydrogen after RF excitation?
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What is the condition of magnetic moments being in different places on the precessional path at a specific moment called?
What is the condition of magnetic moments being in different places on the precessional path at a specific moment called?
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What is the phenomenon when an object is exposed to a frequency similar to its natural oscillation frequency?
What is the phenomenon when an object is exposed to a frequency similar to its natural oscillation frequency?
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What process is primarily responsible for the signal captured in MRI during relaxation?
What process is primarily responsible for the signal captured in MRI during relaxation?
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Which of the following terms describes the loss of phase coherence in MRI?
Which of the following terms describes the loss of phase coherence in MRI?
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What is the term for the spacing between each echo in a Fast Spin Echo (FSE) sequence?
What is the term for the spacing between each echo in a Fast Spin Echo (FSE) sequence?
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Which of the following best describes an electromagnet?
Which of the following best describes an electromagnet?
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What does the term 'Apparent Diffusion Coefficient (ADC)' indicate?
What does the term 'Apparent Diffusion Coefficient (ADC)' indicate?
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In MRI, what is the effective TE referred to?
In MRI, what is the effective TE referred to?
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What signal is produced as the transverse coherent magnetization decreases?
What signal is produced as the transverse coherent magnetization decreases?
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How does TR affect the imaging process in MRI?
How does TR affect the imaging process in MRI?
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What does TE specifically control in MRI imaging?
What does TE specifically control in MRI imaging?
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Which of the following is NOT considered an extrinsic contrast parameter in MRI?
Which of the following is NOT considered an extrinsic contrast parameter in MRI?
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What primarily influences the decay of the voltage induced in the receiver coil?
What primarily influences the decay of the voltage induced in the receiver coil?
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Which statement best describes flip angle in the context of MRI?
Which statement best describes flip angle in the context of MRI?
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Which parameter specifically affects the decay period following the removal of an RF excitation pulse?
Which parameter specifically affects the decay period following the removal of an RF excitation pulse?
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What role does the 'b' value play in MRI imaging?
What role does the 'b' value play in MRI imaging?
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Which factor is considered an intrinsic contrast mechanism in MRI?
Which factor is considered an intrinsic contrast mechanism in MRI?
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What characterizes the term 'dephasing' in MRI?
What characterizes the term 'dephasing' in MRI?
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Which of the following is primarily involved in achieving resonance in MRI?
Which of the following is primarily involved in achieving resonance in MRI?
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Which parameter is affected by the timing of RF pulses in an MRI sequence?
Which parameter is affected by the timing of RF pulses in an MRI sequence?
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In the context of MRI, what does the term 'electromagnet' refer to?
In the context of MRI, what does the term 'electromagnet' refer to?
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How does the net magnetization vector (NMV) behave during the free induction decay (FID) signal after the RF pulse is turned off?
How does the net magnetization vector (NMV) behave during the free induction decay (FID) signal after the RF pulse is turned off?
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What does the free induction decay (FID) signal primarily result from?
What does the free induction decay (FID) signal primarily result from?
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What effect does dephasing have on the magnetic moments of hydrogen nuclei over time?
What effect does dephasing have on the magnetic moments of hydrogen nuclei over time?
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What is the relationship between resonance and the energy acquired by a nucleus?
What is the relationship between resonance and the energy acquired by a nucleus?
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Which factor directly influences the amount of T1 relaxation before the signal is read?
Which factor directly influences the amount of T1 relaxation before the signal is read?
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What is the significance of echo time (TE) in MRI signal acquisition?
What is the significance of echo time (TE) in MRI signal acquisition?
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Which factor primarily contributes to the recovery process during FID in MRI?
Which factor primarily contributes to the recovery process during FID in MRI?
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What does the flip angle impact in MRI imaging?
What does the flip angle impact in MRI imaging?
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Which of the following is a consequence of an RF pulse affecting the magnetic moments of hydrogen nuclei?
Which of the following is a consequence of an RF pulse affecting the magnetic moments of hydrogen nuclei?
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In the context of MRI, what does increasing the turbo-factor (ETL/TF) affect?
In the context of MRI, what does increasing the turbo-factor (ETL/TF) affect?
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What does the term Larmor frequency refer to in the context of a nucleus in MRI?
What does the term Larmor frequency refer to in the context of a nucleus in MRI?
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What primarily drives the process of relaxation in hydrogen nuclei following RF excitation?
What primarily drives the process of relaxation in hydrogen nuclei following RF excitation?
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Which parameter influences the timing of gradients for generating diffusion-weighted images?
Which parameter influences the timing of gradients for generating diffusion-weighted images?
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What is the effect of a shorter repetition time (TR) on imaging?
What is the effect of a shorter repetition time (TR) on imaging?
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Which situation best describes precessional phase in MRI?
Which situation best describes precessional phase in MRI?
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Which of the following best defines the role of echo time (TE) in MRI?
Which of the following best defines the role of echo time (TE) in MRI?
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Which parameter is NOT typically considered an intrinsic contrast mechanism in MRI?
Which parameter is NOT typically considered an intrinsic contrast mechanism in MRI?
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What is primarily affected by the equilibrium state in MRI?
What is primarily affected by the equilibrium state in MRI?
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In the context of MRI, which of the following reflects the characteristics of an electromagnet in use?
In the context of MRI, which of the following reflects the characteristics of an electromagnet in use?
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Which factor contributes the least to the loss of phase coherence in the transverse plane during MRI?
Which factor contributes the least to the loss of phase coherence in the transverse plane during MRI?
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What is the overall purpose of echo train length (ETL) in MRI sequences?
What is the overall purpose of echo train length (ETL) in MRI sequences?
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What primarily determines the amount of T1 relaxation by the time the signal is read?
What primarily determines the amount of T1 relaxation by the time the signal is read?
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Which of the following best describes how echo time (TE) impacts the MRI signal?
Which of the following best describes how echo time (TE) impacts the MRI signal?
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Which parameter is affected by the timing of gradients in diffusion-weighted imaging?
Which parameter is affected by the timing of gradients in diffusion-weighted imaging?
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What is the relationship between TR and the signal decay in MRI?
What is the relationship between TR and the signal decay in MRI?
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What occurs to the net magnetization vector (NMV) after it is influenced only by B0 post RF excitation pulse?
What occurs to the net magnetization vector (NMV) after it is influenced only by B0 post RF excitation pulse?
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Which factor directly contributes to the phenomenon of resonance in MRI?
Which factor directly contributes to the phenomenon of resonance in MRI?
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In MRI, which parameter describes the angle through which the net magnetization vector is rotated?
In MRI, which parameter describes the angle through which the net magnetization vector is rotated?
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What role does dephasing play in MRI signal integrity?
What role does dephasing play in MRI signal integrity?
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How does a greater flip angle typically affect MRI imaging?
How does a greater flip angle typically affect MRI imaging?
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What is the expected behavior of hydrogen nuclei's magnetic moments during the process of relaxation?
What is the expected behavior of hydrogen nuclei's magnetic moments during the process of relaxation?
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What is the primary effect of the time from inversion (TI) on MR imaging?
What is the primary effect of the time from inversion (TI) on MR imaging?
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In MRI, what consequence arises from the inhomogeneities present in the B0 field?
In MRI, what consequence arises from the inhomogeneities present in the B0 field?
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Which of the following best describes the effect of echo train length (ETL) on MRI?
Which of the following best describes the effect of echo train length (ETL) on MRI?
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How does the Faraday law relate to the generation of MRI signals?
How does the Faraday law relate to the generation of MRI signals?
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Which statement best characterizes the frequency at which a nucleus resonates?
Which statement best characterizes the frequency at which a nucleus resonates?
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What is the impact of external RF perturbation on hydrogen nuclei in MRI?
What is the impact of external RF perturbation on hydrogen nuclei in MRI?
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Study Notes
Precessional Phase
- Hydrogen magnetic moments line up at the same place on the precessional path at a given time.
- If hydrogen magnetic moments are at different positions on the precessional path, they are not in phase.
Resonance
- Occurs when an object is exposed to an oscillating perturbation close to its natural frequency of oscillation.
- When a nucleus is exposed to an external force that oscillates similarly to its magnetic moment's natural frequency (Larmor frequency), it gains energy.
### MR Signal
- Motion + electricity = magnet (Faraday's law).
- MR signal generated when hydrogen nuclei precess in a non-uniform magnetic field.
- NMV (Net Magnetization Vector) moves away from B0 (Main Magnetic Field) during resonance.
- Hydrogen magnetic moments move into phase with each other during resonance.
- The FID (Free Induction Decay) signal is the decaying voltage induced in the receiver coil as transverse magnetization decreases, resulting from spin dephasing and relaxation.
- The FID signal is caused by spins freely precessing influenced by B0 alone, decaying with time and inducing a current in the receiver coil.
### Pulse Timing Parameters
- TR (Repetition Time): The time between two RF excitation pulses (milliseconds).
- Affects the amount of longitudinal relaxation between pulses.
- Determines the amount of T1 relaxation before reading the signal.
- TE (Echo Time): The time between an RF excitation pulse and the peak of the signal in the receiver coil (milliseconds).
- Affects the amount of transverse magnetization decay.
- Determines the amount of T2 relaxation before reading the signal.
### Extrinsic Contrast Parameters
- Controlled by the MRI system operator.
- Examples include:
- TR (Repetition Time)
- TE (Echo Time)
- Flip Angle
- Turbo factor/Echo Train length (ETL/TF)
- Time from Inversion (TI)
- 'b' value: reflects the strength and timing of diffusion-weighted gradients
Intrinsic Contrast Mechanism
- Not controlled by the operator.
- Examples include:
- T1 recovery
- T2 decay
- Proton density
- Flow
- ADC (Apparent Diffusion Coefficient)
### MRI Terms
- Dephasing: Loss of phase coherence of signals in the transverse plane.
- Diffusion: Movement of molecules due to random thermal motion.
- Dipole: Magnetic field with north and south poles separated by a distance.
- Display Matrix: Number of pixels in an image, determined by the product of phase and frequency axis.
- Electromagnet: Magnet using coils of wire, typically wound on an iron core, that becomes magnetized when current flows through the coil.
- Equilibrium: A state of balance between opposing forces.
- Excitation: Delivering energy to spinning nuclei with radiofrequency pulses, putting them in a higher energy state.
- Echo spacing: Spacing between each echo in FSE (Fast Spin Echo) sequences.
- Echo train: Series of 180° rephasing pulses and echoes in FSE sequences.
- Echo train length (ETL): Number of 180° RF pulses and echoes in FSE sequences.
- Effective TE: Time between an echo and the RF pulse that initiated it in SSFP (Steady State Free Precession) and FSE sequences.
- Electron Orbit: Electrons orbiting the nucleus in distinct shells, carrying negative charges.
- External Magnetic Field (EMF): A changing magnetic field inducing an electric field, driving a current in a circuit.
MRI Basics
- Precessional Phase: Hydrogen nuclei have magnetic moments that spin in a similar phase, aligned in a specific direction along the precession path.
- Resonance: A phenomenon where an object absorbs energy from an external source when the source's oscillation frequency is close to the object's natural frequency.
- MR Signal: The signal produced by MRI comes from the magnetic moments of hydrogen nuclei, which are aligned in a specific direction by an external magnetic field.
- Free Induction Decay (FID) Signal: The FID signal is the decaying voltage induced in the receiver coil as the net magnetization (NMV) returns to its equilibrium state. This occurs because hydrogen nuclei lose energy and their magnetic moments dephase.
-
Pulse Timing Parameters:
- TR (Repetition Time): Time between two consecutive RF pulses for a single slice. Determines the amount of longitudinal relaxation that occurs before the next pulse.
- TE (Echo Time): Time between the RF pulse and the peak of the signal. Determines the amount of transverse magnetization decay that occurs.
- Flip Angle: Angle to which the NMV is rotated by the RF pulse.
- Turbo-Factor/Echo Train Length (ETL/TF): The number of echoes acquired per excitation pulse.
- Time from Inversion (TI): In inversion recovery sequences, it's the time between an inversion pulse and the 90° pulse.
- ‘b’ value: Indicates the strength and duration of diffusion gradients used in diffusion-weighted imaging.
- Extrinsic Contrast Parameters: Controlled by the system operator and influence contrast in MRI images. Examples include Repetition Time (TR), Echo Time (TE), Flip Angle, Turbo-Factor/Echo Train Length (ETL/TF), TI, and ‘b’ value.
-
Intrinsic Contrast Mechanisms: Not controlled by the operator but contribute to contrast:
- T1 Recovery: The rate at which longitudinal magnetization recovers after RF excitation.
- T2 Decay: The rate at which transverse magnetization decays.
- Proton Density (PD): Concentration of hydrogen nuclei in a tissue.
- Flow: The movement of fluids or blood in the body.
- Apparent Diffusion Coefficient (ADC): Measures the rate of water diffusion in tissue.
- Dephasing: Loss of phase coherence among signals in the transverse plane, leading to signal loss.
- Diffusion: Random movement of molecules due to thermal energy.
- Dipole: A magnetic field with a north and south pole, resulting from a separation of charges.
- Display Matrix: Grid of pixels used to display MRI images.
- Electromagnet: A magnet generated by passing electrical current through coils of wire, often wound around an iron core. Examples include Resistive Magnets and Superconducting Magnets.
- Equilibrium: A state of balance where opposing forces are equal.
- Excitation: Transfer of energy to nuclei via radiofrequency pulses, putting them into a higher energy state and producing a measurable signal.
- Echo Spacing: Time between two consecutive echoes in a fast spin echo (FSE) sequence.
- Echo Train: A series of 180° rephasing pulses and echoes in an FSE sequence.
- Echo Train Length (ETL): The number of 180° RF pulses or the turbo factor, which determines the number of echoes acquired per excitation pulse in an FSE sequence.
- Effective TE: Time between a particular echo and the RF pulse that initiated it in steady-state free precession (SSFP) and FSE sequences.
- Electrons Orbit: Negatively charged particles that orbit the nucleus of an atom in discrete shells.
- External Magnetic Field (EMF): A magnetic field produced externally, which influences the magnetic moments of hydrogen nuclei in MRI.
Precessional Phase
- When hydrogen's magnetic moments are at the same place on the precessional path at a given time, the nuclear magnetic moments (NMV) are in phase.
- When they are at different places on the precessional path at a given time, the NMV are out of phase.
Resonance
- Objects exposed to an oscillating perturbation close to their natural frequency of oscillation undergo resonance.
- Nuclei exposed to an external force with oscillation similar to their Larmor frequency gain energy from the external source.
Result of Resonance
- NMV moves out of alignment with B0.
- Magnetic moments of H nuclei phase together.
MRI Signal
- Faraday's Law states that motion interacting with electricity generates a magnetic field.
- Recovery re-aligns the NMV with B0 after RF pulse excitation.
- Dephasing is the process where the NMV spins lose phase coherence.
Free Induction Decay (FID) Signal
- The FID signal is the voltage induced in the receiver coil as the NMV relaxes, moves back into alignment with B0, and loses phase coherence.
- The relaxation process causes high-energy nuclei to return to the low-energy state, aligning with B0.
- Dephasing is caused by inhomogeneities in the B0 field and interactions between spins.
- The FID signal decays as the transverse coherent magnetization decreases.
Pulse Timing Parameters
- Repetition Time (TR) is the time between RF excitation pulses, measured in milliseconds.
- TR controls the amount of longitudinal relaxation (T1) that occurs before the next RF excitation pulse.
- Echo Time (TE) is the time between the RF excitation pulse and the peak of the signal received in the receiver coil, also measured in milliseconds.
- TE controls the amount of transverse relaxation (T2) that happens before the signal is read.
Extrinsic Contrast Parameters
- These parameters are controlled by the operator, including:
- TR: Repetition Time
- TE: Echo Time
- Flip Angle: The angle the NMV moves due to the RF pulse
- Turbo Factor/Echo Train Length (ETL/TF): The number of echoes used in fast spin echo sequences.
- Time from Inversion (TI): In inversion recovery sequences, the time between the inversion pulse and the excitation pulse.
- b-value: Measure of the strength and timing of diffusion gradients used in diffusion-weighted imaging.
Intrinsic Contrast Mechanism
- These parameters are not controlled by the operator and are influenced by the tissue itself:
- T1 Relaxation: The rate of recovery of longitudinal magnetization.
- T2 Relaxation: The rate of decay of transverse magnetization.
- Proton Density: The concentration of hydrogen atoms in a tissue.
- Flow: The movement of fluids within a tissue.
- Apparent Diffusion Coefficient (ADC): Measure of how fast water molecules diffuse within a tissue.
MRI Terms
- Dephasing: Loss of phase coherence of signals in the transverse plane.
- Diffusion: Random thermal motion of molecules.
- Dipole: A magnetic field with its own north and south poles.
- Display Matrix: The number of pixels in the image, defined by the phase and frequency axes.
- Electromagnet: A magnet created by current flowing through coils of wire.
- Equilibrium: A state of balance between opposing forces.
- Excitation: The process of energizing nuclei with RF pulses to create transverse magnetization.
- Echo Spacing: The time between echoes in fast spine echo sequences.
- Echo Train: A series of echoes generated by rephasing pulses in fast spin echo sequences.
- Echo Train Length (ETL): The number of echoes or turbo factor in fast spin echo sequences.
- Effective TE: The time between an echo and the RF pulse initiating it in SSFP and FSE.
- Electron Orbit: Electrons orbiting the nucleus in shells.
- External Magnetic Field (EMF): A magnetic field generated by moving charges.
Precessional Phase
- In-phase: Magnetic moments of hydrogen are at the same place on the precessional path at a moment in time.
- Out-of-phase: Magnetic moments of hydrogen are at different places on the precessional path at a moment in time.
Resonance
- Phenomenon where an object is exposed to an oscillating perturbation that has a frequency close to its own natural frequency of oscillation.
- When a nucleus is exposed to an external force with an oscillation similar to its magnetic moment’s natural frequency (Larmor frequency) it gains energy from the external source.
- The result of resonance:
- The Net Magnetic Vector (NMV) moves out of alignment away from B0
- The magnetic moments of H nuclei move into phase with each other.
MRI Signal
- Based on Faraday's law: Motion + electricity = magnet.
- MRI signal is generated during the transition from precessional phase to the relaxation phase.
- Relaxation is the process by which hydrogen loses the energy given to it by the RF excitation pulse.
- Dephasing occurs independently of relaxation, losing coherency due to inhomogeneities in B0 field and interactions between spins in tissue.
Free Induction Decay (FID) Signal
- Occurs when the RF excitation pulse is switched off and the NMV is influenced only by B0.
- The NMV realigns with B0 as the hydrogen nuclei lose energy.
- Dephasing creates a decay in transverse coherent magnetization which reduces the magnitude of the voltage induced in the receiver coil.
- This decaying voltage is called the FID signal because it shows the magnetic moments of spins freely precessing under the influence of B0 and the signal decays with time, inducing a current in the receiver coil.
Pulse Timing Parameters
- Repetition Time (TR): Time from one RF excitation pulse to the next for each slice. Measured in milliseconds.
- Echo Time (TE): Time between the RF excitation pulse and the peak of the signal induced in the receiver coil. Measured in milliseconds.
- Flip Angle: The angle through which the NMV is moved by an RF excitation pulse.
- Turbo-factor or Echo Train Length (ETL/TF):
- Time from Inversion (TI):
- ‘b’ value: strength and timing of gradients used to generate diffusion-weighted images.
Extrinsic Contrast Parameters
- Controlled by the system operator
- These include:
- Repetition Time (TR): controls the length of relaxation period
- Echo Time (TE): controls the length of the relaxation period after RF excitation pulse
- Flip Angle:
- Turbo-factor or Echo Train Length (ETL/TF)
- Time from Inversion (TI)
- ‘b’ value:
Intrinsic Contrast Mechanism
- Not controlled by the operator.
- These include:
- T1 Recovery:
- T2 Decay:
- Proton Density:
- Flow:
- Apparent Diffusion Coefficient (ADC): measures the magnitude of diffusion of water molecules within tissue.
MRI Terms
- Dephasing: Loss of phase coherence of signals in the transverse plane.
- Diffusion: Moving molecules due to random thermal motion.
- Dipole: A magnetic field with north and south magnetic poles separated by a finite distance.
- Display Matrix: Total number of pixels, described by the product of phase and frequency axis.
- Electromagnet: Magnet using coils of wire, typically wound on an iron core, producing magnetization when current flows.
- Equilibrium: Balance between opposing forces.
- Excitation: Inducing energy into nuclei via radiofrequency pulses.
- Echo Spacing: Spacing between echoes in FSE.
- Echo Train: Series of 180° rephasing pulses and echoes in a fast spin echo pulse sequence.
- Echo Train Length (ETL): Number of 180° RF pulses, or turbo factor, resulting in echoes in FSE.
- Effective TE: Time between the echo and the RF pulse that initiated it in SSFP and FSE sequences.
- Electron Orbit: Electrons orbit the nucleus in distinct shells with negative charge.
- External Magnetic Field (EMF): Drives current in a circuit induced by a changing magnetic field.
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Test your understanding of magnetic resonance and precessional phase in hydrogen nuclei. This quiz covers key concepts like resonance, MR signals, and the dynamics of magnetic moments in a magnetic field. Enhance your knowledge of the principles that govern magnetic resonance.