18 Questions
What are the two main types of tissue response to necrosis mentioned in the text?
Regeneration and fibrosis
What is the most common type of necrosis described in the text?
Coagulative necrosis
Which of the following organs is NOT commonly affected by coagulative necrosis according to the text?
Brain
What is the main cause of coagulative necrosis described in the text?
Ischemia
What is the hallmark of coagulative necrosis according to the text?
Cell type can still be recognized but cytoplasmic and nuclear details are lost
What is the main mechanism by which coagulative necrosis occurs according to the text?
Protein denaturation
In necrosis, what happens to the nucleus compared to apoptosis?
Disruption in necrosis, chromatin condensation in apoptosis
Which type of cell death involves programmed cell death of tissue?
Apoptosis
Which type of cell death shows intact lysosomes?
Apoptosis
What is one key difference between necrosis and apoptosis in terms of the cell membrane?
Loss of integrity in necrosis, intact with blebbing in apoptosis
Which type of cell death leads to an inflammatory response?
Necrosis
Which feature is common to both necrosis and apoptosis?
'Chromatin condensation' in the nucleus
Which type of necrosis occurs commonly due to ischaemia and bacterial or fungal infections?
Liquefactive Necrosis
What is the microscopic picture of caseous necrosis?
Cystic space containing necrotic cell debris and macrophages
Which type of necrosis starts as ischaemic coagulative necrosis due to endarteritis obliterans then leads to partial liquefaction of the necrotic cells?
Caseous Necrosis
What are the common examples of liquefactive necrosis?
Infarct brain and abscess cavity
In which type of necrosis does the affected area appear soft with a liquefied center containing necrotic debris?
Liquefactive Necrosis
What causes cell lysis more than protein denaturation in liquefactive necrosis?
Degradation of tissue by hydrolytic enzymes
Test your knowledge on specific morphological patterns of necrosis, including coagulative necrosis and liquefactive necrosis. Learn about the different types of necrotic cell changes and their associated characteristics.
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