Morphological Features of Heart Hypertrophy

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Questions and Answers

What is a primary morphological feature of heart hypertrophy related to the structure of the heart?

  • Reduction of cardiac myocytes
  • Increased heart rate
  • Increased ventricular wall thickness (correct)
  • Decreased ventricular wall thickness

Which of the following describes a change in the myocytes during heart hypertrophy?

  • Myocytes decrease in number
  • Myocytes become smaller and less organized
  • Myocytes remain unchanged in size
  • Myocytes become enlarged (correct)

What is a notable nuclear change observed in myocytes during heart hypertrophy?

  • Nuclei that remain unchanged
  • Nuclei that undergo fragmentation
  • Nuclei that become smaller and lighter
  • Nuclei that become enlarged and hyperchromatic (correct)

What type of change is fibrosis in the context of heart hypertrophy?

<p>Replacement of myocytes with scar tissue (C)</p> Signup and view all the answers

Which of the following conditions is closely associated with heart hypertrophy?

<p>Left ventricular hypertrophy (LVH) (C)</p> Signup and view all the answers

Flashcards

Increased Ventricular Wall Thickness

The thickening of the heart ventricular walls, resulting in a stronger, more powerful pump.

Enlarged Cardiac Myocytes

The enlargement of individual heart muscle cells, also known as cardiomyocytes.

Fibrosis

The formation of scar tissue within the heart muscle, which can reduce its flexibility and efficiency.

Altered Myocyte Organization

The disruption of the organized structure of the heart muscle cells, impacting the efficiency of heart contractions.

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Nuclear Changes in Hypertrophy

The nuclei of the heart muscle cells become larger and darker, appearing like boxcars.

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Study Notes

Morphological Features of Heart Hypertrophy

  • Increased Ventricular Wall Thickness: Hypertrophy involves a thickening of the heart's chambers, particularly the ventricular walls.

  • Enlarged Cardiac Myocytes: The individual muscle cells (myocytes) of the heart increase in size.

  • Fibrosis: An accumulation of scar tissue (fibrosis) develops within the heart muscle.

  • Altered Myocyte Organization: The arrangement and structure of the heart muscle cells within the heart's chambers become disorganized.

Nuclear Changes

  • Enlarged and Hyperchromatic Nuclei: The nuclei of the heart muscle cells become larger and stain more darkly. This is often referred to as "boxcar nuclei".

Left Ventricular Hypertrophy (LVH)

  • Specific type of hypertrophy: A common form of hypertrophy affecting the left ventricle of the heart.

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