Questions and Answers
What conditions are associated with Microcytic, Hypochromic anemia? (Select all that apply)
What is indicated by a Macrocytic anemia with RPI > 3?
What conditions are indicated by Macrocytic anemia with RPI = 3? (Select all that apply)
Define Normocytic, Normochromic anemia.
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Study Notes
Microcytic, Hypochromic Anemia
- Characterized by small-sized red blood cells and low hemoglobin concentration
- Relevant conditions include:
- Sideroblastic anemia
- Iron deficiency anemia
- Anemia of chronic disease or inflammation
- Thalassemia
- Lead exposure
- Reticulocyte Production Index (RPI) of 3 indicates adequate marrow response
Macrocytic Anemia (RPI >3)
- Characterized by large-sized red blood cells
- Associated with conditions such as:
- Hemolytic anemia or hemorrhage
- Presence of polychromasia, indicating reticulocyte release in response to hemolysis
Macrocytic Anemia (RPI = 3)
- Blood loss anemia can cause macrocytosis without significant marrow response
- May exhibit variable red blood cell morphology
- Causes of extrinsic hemolytic anemia include:
- Microangiopathic hemolytic anemia (MAHA) due to disseminated intravascular coagulation (DIC), thrombotic thrombocytopenic purpura (TTP), or hemolytic uremic syndrome (HUS)
- Autoimmune conditions leading to hemolysis
- Intrinsic hemolytic causes involve:
- RBC membrane defects
- Enzyme deficiencies
- Hemoglobinopathies
- Paroxysmal nocturnal hemoglobinuria (PNH)
Normocytic, Normochromic Anemia
- Defined by red blood cells that are normal in size and hemoglobin content
- Specific cases or causes not fully detailed in provided information
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Description
This quiz covers the morphologic classification of different types of anemias, including microcytic and macrocytic varieties. Each flashcard features specific conditions associated with abnormal red blood cell morphology and relevant clinical indicators. Test your knowledge of anemia classifications and their characteristics.
