Anemia Classification and Causes
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Questions and Answers

Which factor is NOT considered an intrinsic factor leading to anemia?

  • Malignancy (correct)
  • Sickle cell anemia
  • Viral infection
  • G6PD deficiency
  • What blood index value indicates Normocytic Anemia?

  • 25 – 32 pg (correct)
  • 95 μ3
  • Less than 80 pg
  • More than 32 pg
  • Which infection is NOT listed as an extrinsic factor causing anemia?

  • Malaria
  • Hepatitis (correct)
  • Chloramphenicol
  • Streptococci
  • What is the average volume of a single RBC in cubic micron (μ3) that indicates Microcytic Anemia?

    <p>Less than 80 μ3</p> Signup and view all the answers

    Which drug is NOT mentioned as a potential cause of anemia in the text?

    <p>Penicillin</p> Signup and view all the answers

    What is the classification of anemia based on the size of RBCs and their hemoglobin content?

    <p>Normocytic Normochromic Anemia</p> Signup and view all the answers

    What causes Microcytic Hypochromic Anemia?

    <p>Iron deficiency</p> Signup and view all the answers

    What is the cause of Macrocytic Anemia?

    <p>Vitamin B12 or folic acid deficiency</p> Signup and view all the answers

    What leads to Normocytic Normochromic Anemia?

    <p>Acute blood loss</p> Signup and view all the answers

    Which type of anemia is characterized by a normal size and hemoglobin content of RBCs but a decreased number of RBCs?

    <p>Normocytic Normochromic Anemia</p> Signup and view all the answers

    In the osmotic fragility test, what happens to red blood cells in a hypotonic solution?

    <p>They burst</p> Signup and view all the answers

    What is the normal shape of red blood cells in 0.9% NaCl solution?

    <p>They are normal biconcave disc shaped</p> Signup and view all the answers

    At what percentage of NaCl does hemolysis begin in normal red blood cells according to the text?

    <p>0.45%</p> Signup and view all the answers

    At what percentage of NaCl does hemolysis begin in spherocytosis according to the text?

    <p>0.7%</p> Signup and view all the answers

    In which condition is osmotic fragility increased according to the text?

    <p>Hereditary spherocytosis</p> Signup and view all the answers

    Study Notes

    Anemia Factors

    • Age is NOT considered an intrinsic factor leading to anemia.

    Anemia Classification

    • Anemia is classified based on the size of RBCs and their hemoglobin content.

    Types of Anemia

    • Microcytic Anemia: characterized by a lower than normal RBC volume (average volume < 80 μ3).
    • Microcytic Hypochromic Anemia: caused by iron deficiency or thalassemia.
    • Macrocytic Anemia: caused by vitamin B12 or folate deficiency.
    • Normocytic Normochromic Anemia: characterized by a normal size and hemoglobin content of RBCs but a decreased number of RBCs.

    Osmotic Fragility Test

    • In a hypotonic solution, red blood cells swell and eventually lyse.
    • In a 0.9% NaCl solution, red blood cells maintain their normal shape.
    • Hemolysis begins in normal red blood cells at around 0.48% NaCl.
    • Hemolysis begins in spherocytosis at around 0.32% NaCl.
    • Osmotic fragility is increased in spherocytosis.

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    Description

    Learn about the classification and causes of anemia, including the types based on the size of red blood cells and their hemoglobin content. Explore iron deficiency anemia and its impact on the body's oxygen-carrying capacity.

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