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15 Questions

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Anemia Classification and Causes

Created by

@SteadfastGreekArt

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Questions and Answers

Which factor is NOT considered an intrinsic factor leading to anemia?

Malignancy (correct)

Sickle cell anemia

Viral infection

G6PD deficiency

What blood index value indicates Normocytic Anemia?

25 – 32 pg (correct)

95 μ3

Less than 80 pg

More than 32 pg

Which infection is NOT listed as an extrinsic factor causing anemia?

Malaria

Hepatitis (correct)

Chloramphenicol

Streptococci

What is the average volume of a single RBC in cubic micron (μ3) that indicates Microcytic Anemia?

Less than 80 μ3 Signup and view all the answers

Which drug is NOT mentioned as a potential cause of anemia in the text?

Penicillin Signup and view all the answers

What is the classification of anemia based on the size of RBCs and their hemoglobin content?

Normocytic Normochromic Anemia Signup and view all the answers

What causes Microcytic Hypochromic Anemia?

Iron deficiency Signup and view all the answers

What is the cause of Macrocytic Anemia?

Vitamin B12 or folic acid deficiency Signup and view all the answers

What leads to Normocytic Normochromic Anemia?

Acute blood loss Signup and view all the answers

Which type of anemia is characterized by a normal size and hemoglobin content of RBCs but a decreased number of RBCs?

Normocytic Normochromic Anemia Signup and view all the answers

In the osmotic fragility test, what happens to red blood cells in a hypotonic solution?

They burst Signup and view all the answers

What is the normal shape of red blood cells in 0.9% NaCl solution?

They are normal biconcave disc shaped Signup and view all the answers

At what percentage of NaCl does hemolysis begin in normal red blood cells according to the text?

0.45% Signup and view all the answers

At what percentage of NaCl does hemolysis begin in spherocytosis according to the text?

0.7% Signup and view all the answers

In which condition is osmotic fragility increased according to the text?

Hereditary spherocytosis Signup and view all the answers

Study Notes

Anemia Factors

Age is NOT considered an intrinsic factor leading to anemia.

Anemia Classification

Anemia is classified based on the size of RBCs and their hemoglobin content.

Types of Anemia

Microcytic Anemia: characterized by a lower than normal RBC volume (average volume < 80 μ3).
Microcytic Hypochromic Anemia: caused by iron deficiency or thalassemia.
Macrocytic Anemia: caused by vitamin B12 or folate deficiency.
Normocytic Normochromic Anemia: characterized by a normal size and hemoglobin content of RBCs but a decreased number of RBCs.

Osmotic Fragility Test

In a hypotonic solution, red blood cells swell and eventually lyse.
In a 0.9% NaCl solution, red blood cells maintain their normal shape.
Hemolysis begins in normal red blood cells at around 0.48% NaCl.
Hemolysis begins in spherocytosis at around 0.32% NaCl.
Osmotic fragility is increased in spherocytosis.

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Description

Learn about the classification and causes of anemia, including the types based on the size of red blood cells and their hemoglobin content. Explore iron deficiency anemia and its impact on the body's oxygen-carrying capacity.