16 Questions
What is the class of drug for Morphine?
Narcotic analgesic
How does Morphine act on the central nervous system?
By binding with opioid receptors, altering pain perception and emotional response
What is the primary site of metabolism for Morphine?
Liver and kidneys
What is a contraindication for the use of Morphine?
Allergy to morphine AND/OR adverse drug reaction to morphine
What is a common side effect of Morphine?
Bradycardia
What is the schedule for Morphine?
S8
What is the duration of action of Morphine?
1-2 hours
What is the route of administration for Morphine in CCP?
Subcutaneous injection, Intramuscular injection, Intravenous injection, Intraosseous injection
What is required for treatment outside the listed scope of practice?
Approval from the QAS Clinical Consultation and Advice Line
How is the 'Total maximum dose' calculated when administering combined narcotic therapy?
Using a combination of all morphine and Morphine Milligram Equivalent (MME) medication
What is the maximum incremental dose of morphine for a hypotensive adult patient?
2.5 mg IV or 5 mg IM
What is a suitable analgesic for the treatment of moderate to severe labour pain in full-term mothers in the pre-hospital setting?
Morphine
What is a potential side effect of administering morphine to a pregnant mother?
Neonatal respiratory depression
What is the benefit of adding morphine to midazolam in the intubated patient?
It reduces midazolam requirements and provides analgesia
What is the correct way to administer morphine and midazolam in the intubated patient?
Administered through the same IV line but not mixed
What should be flushed thoroughly with sodium chloride 0.9% following equipment use?
Cannulae and IV lines
Study Notes
Morphine DTP
- Morphine is a narcotic analgesic that acts on the central nervous system by binding with opioid receptors.
Pharmacology of Morphine
- Morphine alters pain perception and emotional response to pain, causing respiratory depression, vasodilation, and slows AV node conduction.
- Metabolized by the liver, kidney, and lungs.
Indications for Use of Morphine
- Significant pain
- Sedation
- Autonomic dysreflexia (with systolic BP > 160 mmHg)
Contraindications for Use of Morphine
- Allergy to morphine and/or adverse drug reaction to morphine
- Kidney disease (renal failure)
Precautions for Use of Morphine
- Hypotension
- Respiratory tract burns
- Respiratory depression and/or failure
- Known narcotics addiction
- Concurrent MAOI therapy (antidepressants)
- Cardiac chest pain
Side Effects of Morphine
- Bradycardia
- Drowsiness
- Hypotension
- Nausea and/or vomiting
- Pinpoint pupils
- Respiratory depression
Presentation and Administration of Morphine
- Available in ampoules, 10mg/1ml morphine sulphate pentahydrate
- Routes of administration: subcutaneous injection (SUBCUT), intramuscular injection (IM), intravenous injection (IV), and intraosseous injection (IO)
Pharmacokinetics of Morphine
- Onset of action: 5-10 minutes (IM), 2-5 minutes (IV)
- Duration of action: 1-2 hours
- Half-life: 2 hours
Special Notes for Morphine
- Ambulance officers must only administer morphine for listed indications and dosing range.
- Total maximum dose must be calculated when combining morphine with other narcotic medications.
- Morphine is suitable for treating moderate to severe labour pain in full-term mothers in the pre-hospital setting, but paramedics must carefully assess risks and benefits for both mother and child.
This quiz assesses knowledge of morphine's effects on the central nervous system, its pharmacology, and indications for use. It covers morphine's action on opioid receptors, respiratory depression, and effects on the body.
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