ATI Pharmacology: Fentanyl and Morphine Flashcards
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Questions and Answers

What is a Fentanyl Patch primarily used for?

  • Antidepressant
  • Sedative (correct)
  • Antibiotic
  • Analgesia
  • What is the expected pharmacologic action of Sedative medications?

    Loss of consciousness and elimination of response to painful stimuli

    Which therapeutic uses are associated with the administration of opioids?

  • Induction and maintenance of anesthesia
  • Moderate sedation
  • Intubation and mechanical ventilation
  • All of the above (correct)
  • What is a significant complication of opioid use?

    <p>Respiratory and cardiovascular depression with high risk for hypotension</p> Signup and view all the answers

    What are some methods of medication administration for opioids?

    <p>All of the above</p> Signup and view all the answers

    What precautions should be taken with morphine administration?

    <p>Avoid use in clients who have a history of mental illness; use cautiously in clients who have respiratory and cardiovascular disease.</p> Signup and view all the answers

    Which substances should be avoided in conjunction with opioids?

    <p>All of the above</p> Signup and view all the answers

    What are key nursing interventions for patients on opioids?

    <p>Assess pain level regularly, monitor vital signs, have naloxone available.</p> Signup and view all the answers

    What vital sign change should be reported immediately when administering opioids?

    <p>Respiratory rate less than 12 per minute</p> Signup and view all the answers

    What should clients be educated about regarding other medications while on opioids?

    <p>Avoid taking other medications that have a CNS effect with opioid medication.</p> Signup and view all the answers

    What indicates effective medication management for opioids?

    <p>All of the above</p> Signup and view all the answers

    Study Notes

    Fentanyl Overview

    • Fentanyl is a potent synthetic opioid used as a sedative, particularly in anesthesia.
    • Administered via IV, IM, transmucosal, and transdermal methods for flexibility in different clinical situations.
    • Useful in inducing and maintaining anesthesia, achieving moderate sedation, and facilitating intubation and mechanical ventilation.

    Expected Pharmacologic Action of Fentanyl

    • Causes loss of consciousness and eliminates response to painful stimuli through central nervous system (CNS) depression.
    • Interactions with various CNS agents can lead to additive effects.

    Therapeutic Uses of Fentanyl

    • Commonly used for induction and maintenance of anesthesia.
    • Provides moderate sedation, usually alongside a non-opioid agent.
    • Critical for intubation and facilitating mechanical ventilation.

    Complications Associated with Fentanyl

    • High risk for respiratory and cardiovascular depression, particularly hypotension.
    • Monitoring is essential due to potential severity of complications.

    Administration Routes for Fentanyl

    • Can be administered through several routes: IV, IM, transmucosal, and transdermal, allowing for tailored patient care.

    Contraindications and Precautions for Fentanyl

    • Not recommended for clients with a history of mental illness due to psychiatric effects.
    • Caution is advised in patients with respiratory or cardiovascular ailments.

    Drug Interactions with Fentanyl

    • Potential for additive CNS depression when combined with alcohol, barbiturates, and opioids.
    • CNS stimulation can occur with amphetamines and cocaine.

    Nursing Interventions for Fentanyl

    • Administer gradually for moderate sedation to avoid severe reactions.
    • Continuous monitoring is critical during and after sedation for signs of respiratory arrest or hypotension.
    • Use large veins for injection to minimize discomfort.

    Patient Education for Fentanyl

    • Advising transportation arrangements post-outpatient procedures is crucial for patient safety.

    Evaluation of Fentanyl Effectiveness

    • Effectiveness is measured by stable vital signs, patient orientation, bowel activity, urination, controlled nausea, and absence of pain during procedures.

    Morphine Sulfate Overview

    • Morphine is a natural opioid used primarily for pain management, categorized as a narcotic.

    Expected Pharmacologic Action of Morphine

    • Acts predominantly on mu receptors and partially on kappa receptors, resulting in analgesia, sedation, euphoria, and respiratory depression.

    Therapeutic Uses of Morphine

    • Effective for relief of moderate to severe pain, sedation, reducing bowel motility, and cough suppression.

    Complications Associated with Morphine

    • Common side effects include respiratory depression, constipation, orthostatic hypotension, urinary retention, sedation, and potential biliary colic.

    Administration Routes for Morphine

    • Can be administered via various routes including oral, subcutaneous, intramuscular, intravenous, epidural, and intrathecal.

    Contraindications and Precautions for Morphine

    • Contraindicated post-biliary tract surgery and during/after delivery in premature infants due to respiratory risks.
    • Caution needed for patients with asthma, obesity, and those having hepatic or renal issues.

    Nursing Interventions for Morphine

    • Regular pain assessments and vital sign monitoring are essential; notify healthcare provider if respiratory rate drops below 12/min.
    • Following controlled substance guidelines and have naloxone ready in case of overdose is advised.
    • Patients with cancer should have a fixed opioid schedule for better pain control.

    Patient Education for Morphine

    • Patients should avoid concurrent use of other CNS-affecting medications to prevent compounded effects.

    Drug Interactions with Morphine

    • Avoid combining morphine with other CNS depressants, alcohol, or anticholinergic agents due to heightened risk of adverse effects.

    Evaluation of Morphine Effectiveness

    • Effectiveness is gauged through pain relief, cough suppression, and resolution of gastrointestinal symptoms like diarrhea.

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    Description

    Test your knowledge on the pharmacology of Fentanyl and Morphine with these flashcards. Each card covers important definitions including expected pharmacologic actions and therapeutic uses. Perfect for students and professionals looking to enhance their understanding of these medications.

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