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Questions and Answers
What is a common side effect of morphine due to the release of histamine from mast cells?
What is a common side effect of morphine due to the release of histamine from mast cells?
- Hypertension
- Bronchodilation
- Bradycardia (correct)
- Tachycardia
Which gastrointestinal effect is associated with opioid analgesics like morphine?
Which gastrointestinal effect is associated with opioid analgesics like morphine?
- Constipation (correct)
- Decreased ileocaecal sphincter spasm
- Relaxation of pyloric sphincter
- Increased intestinal secretions
What is a notable effect of opioids in the CNS that may interfere with ventilation?
What is a notable effect of opioids in the CNS that may interfere with ventilation?
- Truncal rigidity (correct)
- Sedation
- Euphoria
- Antitussive action
Which of the following is a common symptom caused by the stimulation of opioid receptors in the chemoreceptor trigger zone (CTZ)?
Which of the following is a common symptom caused by the stimulation of opioid receptors in the chemoreceptor trigger zone (CTZ)?
Which opioid is specifically mentioned for its antitussive (cough suppressant) action?
Which opioid is specifically mentioned for its antitussive (cough suppressant) action?
In case of morphine poisoning, what is a common treatment strategy to counteract the effects?
In case of morphine poisoning, what is a common treatment strategy to counteract the effects?
What is the active metabolite of morphine?
What is the active metabolite of morphine?
Which opioid is a selective cough suppressant and has good oral bioavailability?
Which opioid is a selective cough suppressant and has good oral bioavailability?
What is the acute lethal dose of morphine in humans?
What is the acute lethal dose of morphine in humans?
In case of adverse drug reactions to morphine, what is the specific antidote mentioned in the text?
In case of adverse drug reactions to morphine, what is the specific antidote mentioned in the text?
What is a common treatment for morphine poisoning according to the text?
What is a common treatment for morphine poisoning according to the text?
What enzyme is responsible for the metabolic activation of codeine to morphine?
What enzyme is responsible for the metabolic activation of codeine to morphine?
Which drug is commonly used in combination with paracetamol, aspirin, or ibuprofen to treat moderate to severe pain?
Which drug is commonly used in combination with paracetamol, aspirin, or ibuprofen to treat moderate to severe pain?
What is the primary adverse effect of an overdose of pethidine?
What is the primary adverse effect of an overdose of pethidine?
Which opioid is 80-100 times more potent than morphine?
Which opioid is 80-100 times more potent than morphine?
What is the common use of codeine as a medication?
What is the common use of codeine as a medication?
What is the half-life of buprenorphine?
What is the half-life of buprenorphine?
Which receptor agonists are being considered for future opioid development due to their potential to provide analgesia without causing addiction?
Which receptor agonists are being considered for future opioid development due to their potential to provide analgesia without causing addiction?
What are the excitatory effects observed in an overdose of pethidine?
What are the excitatory effects observed in an overdose of pethidine?
What distinguishes opioids as strong analgesics?
What distinguishes opioids as strong analgesics?
'Visceral pain' is a significant indication for the use of opioids; what does this term generally refer to?
'Visceral pain' is a significant indication for the use of opioids; what does this term generally refer to?
