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Questions and Answers
Which cells are fused with myeloma cells to produce monoclonal antibodies?
Which cells are fused with myeloma cells to produce monoclonal antibodies?
- B cells (correct)
- Plasma cells
- Natural killer cells
- T cells
What is the advantage of using myeloma cells in the fusion process?
What is the advantage of using myeloma cells in the fusion process?
- They produce antibodies of desired specificity
- They are easier to obtain from animals
- They have a longer life span in vitro
- They can be propagated indefinitely in tissue culture (correct)
What is the result of fusing B cells with myeloma cells?
What is the result of fusing B cells with myeloma cells?
- The myeloma cells lose their ability to grow in the presence of a certain toxic drug
- The myeloma cells acquire the short life span of B cells
- The B cells lose their ability to produce antibodies
- The B cells acquire the immortal property of myeloma tumor (correct)
Which technique is used to generate monoclonal antibodies that are less immunogenic and more suitable for administration to humans?
Which technique is used to generate monoclonal antibodies that are less immunogenic and more suitable for administration to humans?
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Which of the following is a problem with injecting mouse monoclonal antibodies into human subjects?
Which of the following is a problem with injecting mouse monoclonal antibodies into human subjects?
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How are monoclonal antibodies generated using recombinant DNA technology?
How are monoclonal antibodies generated using recombinant DNA technology?
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