Podcast
Questions and Answers
What does MAOI stand for?
What does MAOI stand for?
Monoamine Oxidase Inhibitors
MAOIs irreversibly inhibit ______, leading to higher levels of norepinephrine, serotonin, and dopamine.
MAOIs irreversibly inhibit ______, leading to higher levels of norepinephrine, serotonin, and dopamine.
MAO
Which of the following neurotransmitters are affected by MAOIs?
Which of the following neurotransmitters are affected by MAOIs?
- Norepinephrine
- Serotonin
- Dopamine
- All of the above (correct)
MAOIs are typically the first-line treatment for depression.
MAOIs are typically the first-line treatment for depression.
What is a severe and potentially fatal cardiovascular adverse effect associated with MAOIs?
What is a severe and potentially fatal cardiovascular adverse effect associated with MAOIs?
Which of the following is a contraindication for MAOI use?
Which of the following is a contraindication for MAOI use?
Tyramine-containing foods can be safely consumed while taking MAOIs.
Tyramine-containing foods can be safely consumed while taking MAOIs.
Name a category of drugs, besides other anti-depressants, that can have drug-drug interactions with MAOIs.
Name a category of drugs, besides other anti-depressants, that can have drug-drug interactions with MAOIs.
Flashcards
MAOIs: Core Action
MAOIs: Core Action
Irreversibly inhibit MAO, increasing norepinephrine, serotonin, and dopamine levels.
Pheochromocytoma
Pheochromocytoma
A rare tumor in the adrenal gland.
MAOIs usage
MAOIs usage
last choice antidepressant.
MAOIs: Contraindications
MAOIs: Contraindications
Signup and view all the flashcards
Tyramine + MAOIs Risk
Tyramine + MAOIs Risk
Signup and view all the flashcards
Drug-Food interaction
Drug-Food interaction
Signup and view all the flashcards
Hypertensive Crisis
Hypertensive Crisis
Signup and view all the flashcards
MAOI Drug Interactions
MAOI Drug Interactions
Signup and view all the flashcards
MAOIs: Severe Adverse Effects
MAOIs: Severe Adverse Effects
Signup and view all the flashcards
Drug-Drug interaction
Drug-Drug interaction
Signup and view all the flashcards
Study Notes
- Monoamine Oxidase Inhibitors (MAOIs)
Core Purpose
- Irreversibly inhibit MAO, leading to higher levels of norepinephrine, serotonin, and dopamine
Indications
- Similar to other anti-depressants but typically considered last resort
Adverse effect
- Similar to other antidepressants but much more severe and fatal (cardiovascular)
Contraindication
- Pheochromocytoma (rare tumor that grows in an adrenal gland)
- CV disease
- Abnormal CNS vessels of defects
- History of headaches
- Renal and hepatic impairment
Drug-Food
- Tyramine containing foods will accumulate in the body, leading to hypertensive crisis and possible stroke (CVA)
Drug-Drug
- Other antidepressants
- Some diabetes
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
Monoamine Oxidase Inhibitors (MAOIs) inhibit MAO, increasing norepinephrine, serotonin, and dopamine levels. They're used when other antidepressants fail due to severe side effects, including cardiovascular issues. MAOIs are contraindicated in patients with pheochromocytoma, CV disease and renal and hepatic impairment.
