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What is the function of the primase complex during DNA replication?
What is the main function of DNA polymerase-δ during lagging strand synthesis?
What is the purpose of ribonucleases during DNA replication?
What is the characteristic feature of telomeres?
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What is the function of the PCNA ring during DNA replication?
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What is the characteristic of the G-rich strand at the telomere end?
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What is the mode of DNA replication?
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Which of the following is NOT a function of helicase in DNA replication?
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What is the function of RPA in DNA replication?
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What is the main function of topoisomerase in DNA replication?
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Which DNA polymerase is involved in leading strand synthesis?
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What is the function of PCNA in DNA replication?
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What is the primary function of primase in DNA replication?
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What is the characteristic of lagging strand synthesis?
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What is the primary reason for the formation of loops at the telomere?
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What is the main function of telomeres?
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What happens to telomeres during DNA replication?
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What is the consequence of short telomeres?
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What is the role of telomere-specific proteins?
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What is the effect of short telomeres on the CNS?
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What is the relationship between telomere shortening and disease?
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What is the function of the ORC and MCM proteins in DNA replication?
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In what direction does DNA synthesis always proceed?
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What is the function of DNA primers in DNA replication?
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What is the result of DNA replication?
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What is the function of helicase in DNA replication?
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What is the function of topoisomerase in DNA replication?
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How does DNA polymerase initiate chain synthesis?
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What is the characteristic of DNA replication?
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What is the direction of DNA replication?
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ThePrimase complex synthesizes short RNA _______ of approximately 10nt.
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The _______ strand is synthesized by a complex of DNA polymerase δ (Pol δ)-PCNA-Rfc.
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During concurrent DNA replication, both the _______ and leading strands are synthesized simultaneously.
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Ribonucleases are required to remove the RNA _______ from the newly synthesized strand.
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A DNA polymerase adds deoxynucleotides to the free hydroxyl group at the ______ end of the primer
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Primases are required to form the ______ primers required for DNA polymerases
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The G-rich strand at the telomere end terminates in a single-stranded _______ of approximately 75-300 nucleotides.
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DNA replication is described as ______-discontinuous due to the different mechanisms of leading and lagging strand synthesis
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Topoisomerases are required to ______ the tensions created by the replication bubble
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Helicases are required for the ______ of the parental DNA strands
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Most eukaryotic chromosomes bend back on themselves to form a physical ______ at the telomere.
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The main function of telomeres is ______.
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Telomeres are recognized by a series of proteins that can be classified as ______ proteins and telomere non-specific proteins.
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Short telomeres play a central role in the development of ______ diseases.
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Telomere shortening leads to ______.
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DNA replication is _______________, meaning that each new DNA has one ‘old’ strand and one ‘new’ strand.
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The pre-_____________________ complex is formed by ORC proteins and MCM proteins that recognize origins of replication.
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DNA polymerase requires a short, preexisting RNA or DNA strand, called a _______________, to begin chain growth.
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DNA replication is _______________, meaning that it starts at the origin of replication and proceeds in both directions.
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The enzymatic activity of DNA polymerase is essential for DNA replication, but it cannot initiate chain synthesis de novo and requires a _______________.
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