Molecular Basis of Inheritance

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Thomas Hunt Morgan proved inheritance is carried on ______ through:

chromosomes

Frederick Miescher discovered the chemical makeup of DNA by isolating the ______ in 1869:

nuclein

Walter Flemming stained nuclei with ______ dye and found a basophilic substance which he named “chromatin”:

aniline

Eduoard Zacharias found that removing ______ from chromosomes caused it to stop taking up stains:

DNA

The substance discovered by Miescher, which is a mixture of proteins and other molecules, is now called ______:

chromatin

Frederick Griffith revealed the ______________ factor in 1928.

transforming

The outer coat of bacteria prevents the ______________ system from working against the bacteria.

immune

Avery, McCarthy, and Macleod concluded that ______________ is the molecule of inheritance.

DNA

Hershey and Chase worked with ______________ Bacteriophage to determine the molecule of inheritance.

T2

Radioactive ______________ was used to label the viruses in Hershey and Chase's experiment.

sulfur

Erwin Chargaff noticed that the bases Adenine and Thymine, and Cytosine and Guanine all had the same ______________.

proportion

Adenosine and Guanine are classified as ______________.

purines

Rosalind Franklin did X-ray crystallography on a ______________ DNA molecule.

crystalized

Watson and Crick made a model of the DNA ______________.

structure

Griffith injected heat-killed smooth cells and living rough cells into mice, and they all ______________.

died

Explore the historic discoveries of Thomas Hunt Morgan and Frederick Miescher, pioneers in the field of molecular biology. Learn about their findings on chromosomes, genes, and the chemical makeup of DNA. Test your knowledge on the milestones in understanding the molecular basis of inheritance.

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