Module BL1004: Animal Physiology Overview

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Questions and Answers

What are the three primary functions of the nervous system?

  • Sensory input, reaction, and perception
  • Learning, memory, and sensation
  • Sensory input, integration, and motor output (correct)
  • Integration, respiration, and movement

Which part of the nervous system is responsible for processing sensory information?

  • Peripheral nervous system
  • Central nervous system (correct)
  • Cerebral cortex
  • Autonomic nervous system

What is the primary role of ganglia in the nervous system?

  • Regulation of body temperature
  • Nourishment of neurons
  • Integration and processing of information (correct)
  • Transmission of electrical impulses

What term describes the long extension of a neuron that transmits signals?

<p>Axon (A)</p> Signup and view all the answers

What is the resting potential of a neuron?

<p>The electrical charge across the plasma membrane when not sending signals (B)</p> Signup and view all the answers

Which component is essential for the nourishment and structural integrity of neurons?

<p>Glia (C)</p> Signup and view all the answers

How does sensory information typically reach the brain?

<p>Through sensory neurons to interneurons (C)</p> Signup and view all the answers

What primary function do motor neurons serve in the nervous system?

<p>Triggering muscle or gland activity (B)</p> Signup and view all the answers

Where are action potentials formed in myelinated axons?

<p>At the nodes of Ranvier (B)</p> Signup and view all the answers

What process describes the jumping of action potentials between the nodes of Ranvier?

<p>Saltatory conduction (A)</p> Signup and view all the answers

What primarily characterizes chemical synapses?

<p>Use of neurotransmitters (C)</p> Signup and view all the answers

Which statement is true concerning presynaptic neurons?

<p>They synthesize and package neurotransmitters. (C)</p> Signup and view all the answers

What happens to neurotransmitters after their release into the synaptic cleft?

<p>They can diffuse, be taken up, or be degraded. (B)</p> Signup and view all the answers

In which type of animals is cephalization most prominently observed?

<p>Bilaterally symmetrical animals (B)</p> Signup and view all the answers

What best describes a nerve net in simple nervous systems?

<p>A series of interconnected nerve cells without central organization (A)</p> Signup and view all the answers

Which of the following is NOT a characteristic of direct synaptic transmission?

<p>Immediate hormonal response (D)</p> Signup and view all the answers

What primarily maintains the concentration gradients of K+ and Na+ across the plasma membrane in a neuron?

<p>Sodium-potassium pumps (C)</p> Signup and view all the answers

What causes the negative charge within a resting neuron?

<p>Trapped anions (D)</p> Signup and view all the answers

During the refractory period after an action potential, why can a second action potential not be initiated?

<p>Na+ channels are temporarily inactivated (C)</p> Signup and view all the answers

How does myelin sheath affect the conduction speed of action potentials?

<p>It increases conduction speed (C)</p> Signup and view all the answers

What occurs at the site where an action potential is generated in the axon?

<p>An electrical current depolarizes the nearby region (A)</p> Signup and view all the answers

What role does the Na+ K+ pump play during the repolarization phase of the action potential?

<p>It restores the membrane to its original polarized condition (A)</p> Signup and view all the answers

What prevents an action potential from traveling backwards along the axon?

<p>Refractory Na+ channels (B)</p> Signup and view all the answers

What is the primary factor that increases the speed of action potentials in vertebrate axons?

<p>Increased diameter of the axon (A)</p> Signup and view all the answers

What primary function does the midbrain serve?

<p>Receipt and integration of sensory information (D)</p> Signup and view all the answers

Which part of the brain is essential for coordinating motor skills and error checking during physical activities?

<p>Cerebellum (D)</p> Signup and view all the answers

What role does the hypothalamus play in the vertebrate brain?

<p>Controlling basic survival behaviors (C)</p> Signup and view all the answers

Which structure serves as the main input center for sensory information to the cerebrum?

<p>Thalamus (C)</p> Signup and view all the answers

Which lobe of the cerebral cortex would primarily process visual information?

<p>Occipital lobe (B)</p> Signup and view all the answers

What structure connects the right and left cerebral hemispheres?

<p>Corpus callosum (B)</p> Signup and view all the answers

Which part of the brain is largely responsible for emotional responses?

<p>Limbic system (A)</p> Signup and view all the answers

Which function is primarily attributed to the medulla oblongata?

<p>Regulation of breathing and cardiovascular activity (A)</p> Signup and view all the answers

What is the primary function of the peripheral nervous system (PNS)?

<p>It transmits information to and from the central nervous system. (B)</p> Signup and view all the answers

What differentiates gray matter from white matter in the central nervous system?

<p>Gray matter contains neuron cell bodies and unmyelinated axons. (D)</p> Signup and view all the answers

Which animal is an example of a more sophisticated nervous system structure among invertebrates?

<p>Leech (D)</p> Signup and view all the answers

What type of neural response is triggered when a doctor taps the knee?

<p>Reflex response (C)</p> Signup and view all the answers

In vertebrates, where does the central nervous system primarily reside?

<p>Within the brain and spinal cord. (A)</p> Signup and view all the answers

Which type of neurons in the PNS carry information away from the central nervous system?

<p>Efferent neurons (A)</p> Signup and view all the answers

Which component is NOT part of the central nervous system?

<p>Cranial nerves (D)</p> Signup and view all the answers

The role of ganglia in the nervous system is to:

<p>Serve as clusters of neurons. (D)</p> Signup and view all the answers

What is the primary function of the motor system in the peripheral nervous system?

<p>Carries signals to skeletal muscles (D)</p> Signup and view all the answers

Which division of the autonomic nervous system is responsible for the body's 'fight or flight' response?

<p>Sympathetic division (A)</p> Signup and view all the answers

Which of the following actions is primarily stimulated by the parasympathetic division?

<p>Stimulating salivary gland secretion (D)</p> Signup and view all the answers

How does the sympathetic division affect the heart?

<p>Accelerates the heart rate (B)</p> Signup and view all the answers

What is the role of the enteric division in the autonomic nervous system?

<p>Manages functions of the digestive system (A)</p> Signup and view all the answers

What effect does the sympathetic division have on bronchial tubes in the lungs?

<p>Relaxes bronchial tubes (C)</p> Signup and view all the answers

What happens to the pupil of the eye when the parasympathetic division is activated?

<p>Constricts the pupil (A)</p> Signup and view all the answers

Which of the following best describes the relationship between the sympathetic and parasympathetic divisions?

<p>They have antagonistic effects on target organs (A)</p> Signup and view all the answers

Which organ's activity is inhibited by the sympathetic division?

<p>Stomach (C)</p> Signup and view all the answers

What is the primary role of the PNS in relation to sensory neurons?

<p>Transmits sensory information to the central nervous system (B)</p> Signup and view all the answers

Which part of the brain contains centers for integrating sensory information?

<p>Midbrain (D)</p> Signup and view all the answers

What is a primary function of the cerebellum?

<p>Coordinating motor skills (A)</p> Signup and view all the answers

Which structure serves as the primary output center for motor information leaving the cerebrum?

<p>Thalamus (C)</p> Signup and view all the answers

What is the function of the hypothalamus in the vertebrate brain?

<p>Regulating homeostasis and survival behaviors (B)</p> Signup and view all the answers

What is the role of the corpus callosum in the brain?

<p>Facilitating communication between cerebral hemispheres (C)</p> Signup and view all the answers

Which lobe of the cerebral cortex is primarily responsible for processing auditory information?

<p>Temporal lobe (D)</p> Signup and view all the answers

What structures are included in the limbic system?

<p>Amygdala and hippocampus (B)</p> Signup and view all the answers

Which of the following accurately describes the primary characteristic of the cerebral cortex?

<p>It is the largest and most complex part of the brain. (C)</p> Signup and view all the answers

Which component of the central nervous system primarily contains neuron cell bodies and unmyelinated axons?

<p>Gray matter (D)</p> Signup and view all the answers

What function do afferent neurons in the peripheral nervous system serve?

<p>Transmit information to the CNS (D)</p> Signup and view all the answers

In which of the following animals would you expect to find a more sophisticated nervous system structure as opposed to a simple nerve net?

<p>Leech (B)</p> Signup and view all the answers

What is the primary role of the spinal cord in the central nervous system?

<p>Transmit information to and from the brain (C)</p> Signup and view all the answers

Which statement describes the peripheral nervous system?

<p>Transmits information to and from the CNS (D)</p> Signup and view all the answers

What type of synapse uses chemical neurotransmitters to transmit information?

<p>Chemical synapse (D)</p> Signup and view all the answers

What type of neural response is primarily associated with reflex actions?

<p>Involuntary responses (C)</p> Signup and view all the answers

Which of the following structures is a cluster of neurons found in the peripheral nervous system?

<p>Ganglia (B)</p> Signup and view all the answers

What is the function of ligand-gated ion channels in the postsynaptic cell?

<p>To generate a postsynaptic potential (C)</p> Signup and view all the answers

Which structure connects the synaptic terminal of a neuron to another cell?

<p>Synapse (D)</p> Signup and view all the answers

What is primarily responsible for the reflex action of the knee-jerk response when a doctor taps the knee?

<p>The spinal cord (A)</p> Signup and view all the answers

What primarily characterizes saltatory conduction in myelinated axons?

<p>Jumping of action potentials between nodes (C)</p> Signup and view all the answers

In which type of nervous system organization is cephalization primarily observed?

<p>Bilateral symmetry (B)</p> Signup and view all the answers

What occurs to neurotransmitters after they have been released into the synaptic cleft?

<p>They may diffuse, be taken up, or degraded (C)</p> Signup and view all the answers

At the nodes of Ranvier, what type of channels are primarily responsible for action potential generation?

<p>Voltage-gated Na+ channels (C)</p> Signup and view all the answers

What structure serves as a series of interconnected nerve cells in the simplest nervous systems?

<p>Nerve net (D)</p> Signup and view all the answers

Which ion is primarily responsible for creating the negative charge inside a resting neuron?

<p>K+ (D)</p> Signup and view all the answers

What role does the sodium-potassium pump play in neuronal function?

<p>It maintains K+ and Na+ concentration gradients. (A)</p> Signup and view all the answers

During the refractory period, what effect do inactivated Na+ channels have on the action potential?

<p>They prevent a second action potential from being initiated. (A)</p> Signup and view all the answers

What is the primary reason that action potentials travel in one direction along an axon?

<p>Inactivated Na+ channels prevent backward travel. (B)</p> Signup and view all the answers

How does the myelin sheath affect the speed of action potentials?

<p>It increases conduction speed. (A)</p> Signup and view all the answers

What primarily occurs at the site where an action potential is generated in the axon?

<p>Sodium channels open, causing depolarization. (D)</p> Signup and view all the answers

What happens to the equilibrium between K+ and Na+ during the resting potential?

<p>K+ concentration is greater inside the cell. (D)</p> Signup and view all the answers

What is the effect of a myelin sheath on the nodes of Ranvier in an axon?

<p>It allows for saltatory conduction. (D)</p> Signup and view all the answers

What primary function does the autonomic nervous system serve?

<p>Regulates involuntary actions in the internal environment (A)</p> Signup and view all the answers

Which division of the peripheral nervous system primarily stimulates digestion?

<p>Parasympathetic division (B)</p> Signup and view all the answers

How does the sympathetic division affect heart rate?

<p>Accelerates it (A)</p> Signup and view all the answers

Which of the following is a characteristic action of the parasympathetic division?

<p>Constricts pupil of the eye (D)</p> Signup and view all the answers

What main role does the enteric division of the autonomic nervous system play?

<p>Regulates gastrointestinal functions (B)</p> Signup and view all the answers

Which action is typically inhibited by the sympathetic division?

<p>Gallbladder activity (D)</p> Signup and view all the answers

Which effect results from sympathetic stimulation of the lungs?

<p>Relaxation of bronchi (A)</p> Signup and view all the answers

What is the primary role of the motor system in the peripheral nervous system?

<p>Carries signals to skeletal muscles for voluntary actions (D)</p> Signup and view all the answers

What effect does the parasympathetic division have on the bladder?

<p>Promotes emptying (A)</p> Signup and view all the answers

What is the primary purpose of interneurons in the nervous system?

<p>Integrate and process sensory information (D)</p> Signup and view all the answers

What characteristic primarily defines dendrites in a neuron?

<p>They receive signals from other neurons. (B)</p> Signup and view all the answers

How is information transmitted along a neuron?

<p>By changes in membrane potential along the neuron (A)</p> Signup and view all the answers

What role do glial cells play in the nervous system?

<p>Provide structural support and nourishment to neurons (B)</p> Signup and view all the answers

What accurately describes the process of motor output in the nervous system?

<p>It triggers gland activity or muscle movement as a response. (C)</p> Signup and view all the answers

Which component of the nervous system is primarily responsible for regulating internal body functions?

<p>Autonomic nervous system (D)</p> Signup and view all the answers

What is the significance of membrane potential in neurons?

<p>It creates the conditions necessary for transmitting signals. (D)</p> Signup and view all the answers

What best describes the function of sensory neurons in the nervous system?

<p>They detect stimuli and transmit information to the CNS. (D)</p> Signup and view all the answers

Flashcards

Nervous System

The network of nerve cells that controls and coordinates all bodily functions.

Central Nervous System (CNS)

The part of the nervous system that processes information and generates responses. It includes the brain and spinal cord.

Peripheral Nervous System (PNS)

The part of the nervous system that connects the CNS to the rest of the body. It carries sensory information to the CNS and motor commands from the CNS to muscles and glands.

Neurons

Specialized cells that transmit signals within the body.

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Dendrites

Highly branched extensions of a neuron that receive signals from other neurons.

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Axon

A long extension of a neuron that transmits signals from its terminal branches to other cells at synapses.

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Membrane Potential

The difference in electrical charge across the plasma membrane of a neuron.

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Resting Potential

The membrane potential of a neuron not sending signals.

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Synapse

A junction between two neurons where communication occurs.

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Saltatory Conduction

The process by which action potentials jump between the nodes of Ranvier in myelinated axons.

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Electrical Synapse

A type of synapse where electrical current flows directly from one neuron to another.

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Chemical Synapse

A type of synapse where a chemical neurotransmitter carries information across the synaptic cleft.

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Presynaptic Neuron

The neuron that releases the neurotransmitter at a synapse.

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Postsynaptic Neuron

The neuron that receives the neurotransmitter at a synapse.

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Neurotransmitter

A chemical messenger that transmits information across the synapse.

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Cephalization

The clustering of sensory organs at the front end of the body in bilaterally symmetrical animals.

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Sodium-Potassium Pump

The sodium-potassium pump actively moves sodium ions (Na+) out of the neuron and potassium ions (K+) into the neuron, maintaining the concentration gradients.

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Chemical Potential to Electrical Potential

When ion channels open, the concentration gradients created by the sodium-potassium pump drive the movement of ions, generating an electrical potential across the membrane.

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Refractory Period

A period after an action potential where a neuron cannot be stimulated to fire another action potential, ensuring that the impulse travels in one direction only.

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Conduction of Action Potentials

The process by which an action potential travels along the axon, regenerating itself at each point.

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Axon Diameter and Action Potential Speed

The speed of an action potential is directly proportional to the diameter of the axon.

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Myelin Sheath

A fatty sheath that surrounds the axon of some neurons, increasing the speed of action potential conduction.

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Glia and Myelin Formation

Glia are supporting cells in the nervous system, and they play a role in forming the myelin sheath: Oligodendrocytes in the CNS and Schwann cells in the PNS.

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Central Nervous System (CNS) in simpler animals

Found in simpler cephalized animals like flatworms, it's a brain and nerve cords, forming a network for information flow.

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Brain in simpler animals

Part of the CNS, responsible for processing information and generating responses.

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Nerve cords in simpler animals

Part of the CNS, extending along the body, carrying signals to and from the brain.

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Central Nervous System (CNS) in vertebrates

Part of the CNS in vertebrates, including brain and spinal cord, processing information and generating responses.

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Gray matter in vertebrates

Part of the CNS, containing neuron cell bodies, dendrites, and unmyelinated axons, responsible for processing information.

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White matter in vertebrates

Part of the CNS, containing bundles of myelinated axons, responsible for faster signal transmission.

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Reflex

The body's automatic response to a stimulus. For example, a knee-jerk reflex triggered by a doctor's mallet.

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What are the functions of the brainstem's three parts?

The midbrain is involved in processing sensory information, the pons regulates breathing, and the medulla oblongata controls essential functions like breathing, heart rate, and digestion.

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What is the role of the cerebellum?

The cerebellum is crucial for coordination and accuracy during movement, perception, and thinking. It also helps with learning and remembering motor skills like hand-eye coordination.

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What are the functions of the three regions within the diencephalon?

The epithalamus generates cerebrospinal fluid and includes the pineal gland, while the thalamus acts as a sensory input hub to the cerebrum and a motor output hub. The hypothalamus regulates essential bodily processes like hunger, thirst, and temperature.

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What is the structure of the cerebrum?

The cerebrum consists of two hemispheres, each having a cerebral cortex (gray matter) and white matter with basal nuclei. In humans, the cerebral cortex is the largest and most complex part of the brain.

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What is the role of the corpus callosum?

The corpus callosum is a thick band of axons that connects the two hemispheres of the cerebrum, enabling communication between them. The right hemisphere controls the left side of the body, and vice versa.

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What are the functions and lobes of the cerebral cortex?

The cerebral cortex is responsible for controlling voluntary movement and cognitive functions. Each hemisphere has four lobes: frontal, temporal, occipital, and parietal. Each lobe contains sensory areas and association areas where information is integrated.

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What is the role of the limbic system in emotions?

The limbic system is involved in generating and experiencing emotions. It's a ring of structures surrounding the brainstem, including the amygdala, hippocampus, and parts of the thalamus.

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Autonomic Nervous System

The part of the peripheral nervous system that controls involuntary bodily functions such as heart rate, digestion, and breathing.

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Sympathetic Division

The division of the autonomic nervous system that generally prepares the body for 'fight or flight' responses. It increases heart rate, dilates pupils, and redirects blood flow to muscles.

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Parasympathetic Division

The division of the autonomic nervous system that generally promotes 'rest and digest' activities. It slows heart rate, constricts pupils, and stimulates digestion.

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Enteric Division

The part of the autonomic nervous system that controls the digestive system. It is a network of neurons within the walls of the digestive tract.

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Antagonistic Effects

The ability of the sympathetic and parasympathetic divisions to have opposite effects on target organs, ensuring a balanced and controlled internal environment.

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Brainstem

The part of the brain that connects the cerebrum and cerebellum to the spinal cord. It controls vital functions like breathing, heart rate, and blood pressure.

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Regional Specialization

The specialized areas of the brain responsible for different functions, such as sensory processing, motor control, and emotions.

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Efferent Neurons

The process of conducting information from the brain to the body, for example, carrying motor commands to muscles.

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Afferent Neurons

The process of transmitting information from the body to the brain, for example, carrying sensory information from the senses to the brain.

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Locomotion

The process of moving the body, which is controlled by the motor system of the peripheral nervous system.

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Nerve Net

A series of interconnected nerve cells that forms a network for communication in simpler animals.

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What is resting potential?

The difference in electrical charge across a neuron's membrane when it's not transmitting signals. It's like a battery, with one side being slightly more negative than the other.

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How is resting potential maintained?

Sodium-potassium pumps embedded in the neuron's membrane actively move sodium ions out and potassium ions in, creating concentration gradients. It's like a bouncer letting more potassium in and more sodium out.

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How does chemical potential turn into electrical potential?

When ion channels open, the concentration gradients drive the movement of ions, generating an electrical potential difference. It's like opening a gate and letting the stored energy flow out.

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What is the refractory period?

After an action potential, the neuron cannot be stimulated again for a brief period. This ensures the signal travels in one direction only and prevents backward propagation. It's like a one-way street for signals.

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How does an action potential travel?

An action potential travels down the axon by regenerating itself along the way, but it's prevented from traveling backward by the inactivated sodium channels. It's like a domino effect, but only going forward.

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How does axon diameter affect action potential speed?

The speed of an action potential increases with the diameter of the axon because the signal has more space to travel. It's like a wider pipe for the signal to flow through.

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How does myelin affect action potential speed?

Myelin sheaths, formed by glial cells, insulate the axon, allowing the signal to jump from one node to another, increasing the speed of transmission. It's like jumping over obstacles instead of hopping through them.

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What are glial cells and their role in myelin?

These are specialized cells - oligodendrocytes (CNS) and Schwann cells (PNS) - involved in the formation of myelin, an insulating layer around the axon. They're like helpers for the signal to travel faster.

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What is the function of the nervous system?

The nervous system is the body's control center, responsible for receiving information from the environment, processing it, and coordinating responses.

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How does the nervous system communicate?

The nervous system uses three key functions for communication: sensory input, integration, and motor output. Sensory neurons detect stimuli, interneurons in the CNS process information, and motor neurons trigger responses.

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What are neurons and how do they work?

Neurons are specialized cells that transmit information through electrical signals. They have dendrites receiving signals, an axon transmitting signals, and a cell body containing its machinery.

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What is membrane potential?

The membrane potential is the difference in electrical charge across a neuron's membrane. This difference in charge is critical for transmitting messages.

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What is a synapse and how does it work?

A synapse is a junction between two neurons where communication occurs. Chemicals called neurotransmitters carry signals across the gap between neurons.

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What is cephalization?

Cephalization is the evolutionary development of a head region with concentrated sensory organs. This allows animals to sense their environment more efficiently.

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What is the role of the sodium-potassium pump?

The sodium-potassium pump actively transports sodium ions out of the neuron and potassium ions into the neuron. This creates concentration gradients that are crucial for generating electrical signals.

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Ganglia

A cluster of nerve cell bodies, found in the peripheral nervous system and also within the central nervous system, responsible for processing and relaying information.

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Gray matter

The tissue in the CNS that consists of neuron cell bodies, dendrites, and unmyelinated axons. It is responsible for processing information and generating responses.

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White matter

The tissue in the CNS that consists of bundles of myelinated axons. It is responsible for transmitting information quickly between different parts of the CNS.

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What is the brainstem and what does it do?

The brainstem, located at the base of the brain, connects the cerebrum and cerebellum to the spinal cord. It controls essential functions like breathing, heart rate, and blood pressure.

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What are the functions of the three parts of the brainstem?

The midbrain is involved in sensory information processing, the pons regulates breathing centers in the medulla, and the medulla oblongata controls vital functions like breathing, cardiovascular activity, digestion, and other essential processes.

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What is the cerebellum and what does it do?

The cerebellum is crucial for coordination and accuracy during movement, perception, and thinking. It also plays a role in learning and remembering motor skills, such as hand-eye coordination.

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What are the three regions of the diencephalon and their functions?

The diencephalon develops into three regions: the epithalamus, responsible for generating cerebrospinal fluid and containing the pineal gland; the thalamus, the main input center for sensory information to the cerebrum and the main output center for motor information leaving the cerebrum; and the hypothalamus, which regulates homeostasis and basic survival behaviors like feeding, fighting, fleeing, and reproduction.

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What is the corpus callosum and what does it do?

The corpus callosum is a thick band of axons connecting the two hemispheres of the cerebrum, enabling communication between them. The right hemisphere controls the left side of the body, and vice versa.

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What is the limbic system and what does it do?

The limbic system is responsible for generating and experiencing emotions. It's a ring of structures surrounding the brainstem, including the amygdala, hippocampus, and parts of the thalamus.

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Study Notes

Module BL1004: Animal Physiology

  • This module covers animal physiology
  • Professor Rob McAllen teaches the module
  • The module is part of the School of Biological, Earth & Environmental Sciences, University College Cork, Ireland
  • Contact information is provided for the professor

Nervous System

  • Electric signals in animals (Chapter 48 pg 1125 Campbell)
  • Integrated physiological mechanisms
  • Barnacles on rocky shores are an example
  • Sponge diversity is covered in another section of the presentation

Sponge Diversity

  • Variety of sponges are shown in the presentation

Sponge Film

  • A presentation about sponges

Overview: Command and Control Center

  • Controls feelings, perceptions, and movement
  • Enables learning, remembering, thinking, and awareness
  • Regulates internal body functions and behavior

Overview: Lines of Communication

  • Nervous system has three functions: sensory input, integration, and motor output
  • Sensors detect stimuli to transmit information to sensory neurons
  • Sensory information is processed in the brain or ganglia (interneurons)
  • Motor output leaves the brain or ganglia via motor neurons for muscle/gland activity (Peripheral Nervous System -PNS)
  • Example of the doctor - knee jerk response
  • Neurons are nerve cells for information transfer
  • Signal transmission depends on the path of neurons
  • Processing of information occurs in ganglia (clusters of neurons) or a brain (more complex organization of neurons)

Neuron

  • Function: Transmission of signals
  • Most neurons have dendrites (highly branched extensions) for receiving signals from other neurons
  • Axons extend signals from terminal branches to other cells at synapses
  • Neuron's organelles are in the cell body
  • Neurons are nourished and insulated by glia (essential for the structure and normal functioning of the nervous system)

Neuron - Every cell has a voltage difference across its plasma membrane called membrane potential

  • Messages are transmitted as changes in membrane potential
  • The resting potential is the membrane potential of a neuron not sending signals
  • Ion pumps and ion channels maintain the resting potential of a neuron

Neuron - Formation of the Resting Potential

  • At rest, the concentration of K+ is higher inside the cell, while the concentration of Na+ is higher outside the cell
  • Sodium-potassium pumps use ATP energy to maintain K+ and Na+ gradients across the plasma membrane
  • These concentration gradients represent chemical potential energy
  • The opening of ion channels in the plasma membrane converts chemical potential to electrical potential
  • A neuron at resting potential has many open K+ channels and fewer open Na+ channels; K+ diffuses out of the cell
  • Anions trapped inside the cell contribute to the negative charge inside the neuron
  • In a resting neuron, the currents of K+ and Na+ are equal and opposite, keeping the resting potential steady

Formation of Action Potentials

  • A detailed sequence about how action potentials are formed.
  • Key terms and stages are highlighted
  • Depolarization (stimulus opens sodium channels)
  • Rising phase of the action potential
  • Falling phase of the action potential
  • Undershoot

During the refractory period after an action potential

  • A second action potential cannot be initiated and the impulse moves only in one direction along the axon
  • The refractory period results from a temporary inactivation of the Na+ channels
  • The refractory period is a period of repolarization where the Na+-K+ pump restores the membrane to its original polarized condition

Conduction of Action Potentials

  • Action potentials travel long distances by regenerating themselves along the axon
  • At the generated site, an electrical current depolarizes the neighboring region of the axon membrane, preventing the action potential from traveling backwards.
  • Action potentials move, only, in one direction toward the synaptic terminals

Conduction of Action Potentials

  • Action potential speed increases with the axon's diameter.
  • Vertebrate axons' insulation, by a myelin sheath, increases action potential speed
  • Myelin sheaths are composed of glia (oligodendrocytes in CNS and Schwann cells in PNS)

Conduction of Action Potentials

  • Action potentials are formed only at nodes of Ranvier
  • Action potentials jump between the nodes of Ranvier in a process called saltatory conduction

Neurons communicate with other cells at synapses

  • Synapse is a junction that controls communication between cells
  • At electrical synapses, electrical current flows between neurons
  • At chemical synapses, a neurotransmitter carries information across the gap junction (synapse), which are mostly chemical synapses

There are two types of synapses

  • The synaptic terminal passes information across the synapse in the form of chemical messengers (neurotransmitters)
  • Information is transmitted from a presynaptic cell (neuron) to a postsynaptic cell (neuron, muscle, or gland cell)

Chemical synapses

  • The presynaptic neuron synthesizes and packages neurotransmitters in synaptic vesicles, located in the synaptic terminal.
  • Action potential causes neurotransmitter release.
  • Neurotransmitter diffuses across the synaptic cleft and is received by the postsynaptic cell.

Chemical synapses

  • Direct synaptic transmission involves binding neurotransmitters to ligand-gated ion channels in the postsynaptic cell (generating a postsynaptic potential)
  • After release, the neurotransmitter may diffuse out of the synaptic cleft, be taken up by surrounding cells, or be degraded by enzymes

"Neural Regulation in Animals"

  • Chapter 49 pg 1143 Campbell

Plane or axis of symmetry

  • Different types of symmetry are shown and described (e.g., Radial, Bilateral)

Nervous systems consist of circuits of neurons and supporting cells

  • Simplest animals with nervous systems (cnidarians) have nerve nets (interconnected nerve cells with no central pathway or directional organization).
  • Examples include starfish (nerve net in each arm, connected by radial nerves to a central nerve ring)

Nervous systems consist of circuits of neurons and supporting cells

  • Bilaterally symmetrical animals exhibit cephalization (clustering of sensory organs at the front end of the body).
  • Examples of cephalized animals with CNS include Planarian, Leech, Insect, Chiton and Squid.

In vertebrates

  • CNS is composed of the brain and spinal cord (integration of information occurs here).
  • PNS is composed of nerves and ganglia, transferring information to and from the CNS
  • Diagram showing CNS and PNS in a vertebrate

Central Nervous System

  • The brain and spinal cord contain gray matter (neuron cell bodies, dendrites, and unmyelinated axons) and white matter (bundles of myelinated axons)
  • Diagrams showing gray and white matter arrangement

Organization of the Vertebrate Nervous System

  • A reflex is the body's automatic response to a stimulus.
  • Example: doctor's use of a mallet to trigger a knee-jerk reflex
  • Diagram illustrating the spinal cord's reflex arc components (sensory neuron, interneuron, and motor neuron).

Peripheral Nervous System

  • PNS transmits information to and from the CNS and controls movement and internal environment.
  • Afferent neurons transmit information to the CNS, and efferent neurons transmit information away from the CNS
  • Cranial nerves originate in the brain and mostly terminate in head and upper body organs
  • Spinal nerves originate from the spinal cord extending to the body below the head

Peripheral Nervous System

  • PNS has two functional components: motor system (voluntary) and autonomic nervous system (involuntary)
  • Autonomic nervous system has three divisions: sympathetic, parasympathetic, and enteric.

Peripheral Nervous System (diagram)

  • Shows the relationships between the PNS, motor system, autonomic nervous system (with sympathetic, parasympathetic, and enteric divisions).

The brain

  • The vertebrate brain is regionally specialized.
  • Brainstem coordinates and conducts information between brain centers (midbrain, pons, medulla oblongata).
  • Medulla oblongata controls cardiovascular activity, breathing, swallowing, vomiting, and digestion.
  • Cerebellum coordinates motor function and perceptual/cognitive functions. It plays a role in learning and remembering motor skills (e.g., hand-eye coordination)

The brain

  • Embryonic diencephalon develops into three regions (epithalamus, thalamus, hypothalamus).
  • Epithalamus includes the pineal gland (produces melatonin).
  • Thalamus is the main sensory input center to the cerebrum, and the main output center for motor information to leave the cerebrum.
  • Hypothalamus regulates homeostasis and basic survival behaviors.

The brain

  • Cerebrum has right and left cerebral hemispheres
  • Each hemisphere consists of cerebral cortex(gray matter, overlying white matter and basal nuclei).
  • Cerebral cortex is the largest and most complex part of the brain in humans.

The brain

  • Corpus callosum connects right and left cerebral cortices
  • Right cerebral cortex controls the left side of the body and vice versa.

The brain

  • Cerebral cortex has four lobes: frontal, temporal, occipital, and parietal
  • Each lobe contains primary sensory areas; where information is integrated in association areas.

The limbic system

  • Emotions are generated and experienced by the limbic system and other brain parts, including sensory areas
  • The limbic system is a ring of structures around the brainstem involving the amygdala, hippocampus, and parts of the thalamus
  • Amygdala in the temporal lobe helps store emotional experiences as emotional memory

Memory and Learning

  • Learning occurs through new connections or changes in the strength of existing connections between neurons.
  • Short-term memory is accessed via the hippocampus.
  • Hippocampus also plays a role in forming long-term memories stored in the cerebral cortex

Acknowledgements

  • Majority of content is from Campbell's Biology
  • Dr. Ramiro Crego from the School of BEES contributed to the presentation

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