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10 Questions

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Module 3: Agglutination

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Questions and Answers

What is the purpose of the Coagglutination system using Staphylococcus aureus?

To identify streptococci bacteria (correct)

To determine the presence of rheumatoid factor

To detect autoimmune hemolytic anemia

To measure residual agglutinating particles in a specimen

What is the role of protein A in the Coagglutination reaction?

It adsorbs the FC portion of antibody molecules (correct)

It bridges the distance between IgG cells

It helps in washing cells after combination

It reacts with red blood cells

Which test is known as the Coombs' test according to the text?

Antiglobulin-Mediated Agglutination (correct)

Direct Antiglobulin Test

Particle-counting immunoassay (PACIA)

Indirect Antiglobulin Test

In which condition does the Direct Antiglobulin Test serve as an indicator?

Autoimmune hemolytic anemia Signup and view all the answers

What may cause sources of error in antiglobulin testing according to the text?

Using expired reagents Signup and view all the answers

What is the main characteristic of agglutination?

Clumping of particles due to specific antibody combination Signup and view all the answers

What did Gruber and Durham report in 1896?

Observations of agglutination of bacterial cells by serum Signup and view all the answers

Which factor influences lattice formation in agglutination reactions?

Environmental conditions and relative concentrations of antigen and antibody Signup and view all the answers

What enhance the process of lattice formation in agglutination reactions?

Decreasing buffer's ionic strength Signup and view all the answers

What is the purpose of passive agglutination in laboratory tests?

To coat particles with antigens not normally found on their surfaces Signup and view all the answers