Module 3: Agglutination

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Questions and Answers

What is the purpose of the Coagglutination system using Staphylococcus aureus?

  • To identify streptococci bacteria (correct)
  • To determine the presence of rheumatoid factor
  • To detect autoimmune hemolytic anemia
  • To measure residual agglutinating particles in a specimen

What is the role of protein A in the Coagglutination reaction?

  • It adsorbs the FC portion of antibody molecules (correct)
  • It bridges the distance between IgG cells
  • It helps in washing cells after combination
  • It reacts with red blood cells

Which test is known as the Coombs' test according to the text?

  • Antiglobulin-Mediated Agglutination (correct)
  • Direct Antiglobulin Test
  • Particle-counting immunoassay (PACIA)
  • Indirect Antiglobulin Test

In which condition does the Direct Antiglobulin Test serve as an indicator?

<p>Autoimmune hemolytic anemia (B)</p> Signup and view all the answers

What may cause sources of error in antiglobulin testing according to the text?

<p>Using expired reagents (A)</p> Signup and view all the answers

What is the main characteristic of agglutination?

<p>Clumping of particles due to specific antibody combination (C)</p> Signup and view all the answers

What did Gruber and Durham report in 1896?

<p>Observations of agglutination of bacterial cells by serum (A)</p> Signup and view all the answers

Which factor influences lattice formation in agglutination reactions?

<p>Environmental conditions and relative concentrations of antigen and antibody (D)</p> Signup and view all the answers

What enhance the process of lattice formation in agglutination reactions?

<p>Decreasing buffer's ionic strength (A)</p> Signup and view all the answers

What is the purpose of passive agglutination in laboratory tests?

<p>To coat particles with antigens not normally found on their surfaces (A)</p> Signup and view all the answers

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