MM6113 Molecular Medicine: Reverse Transcription Quiz
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Questions and Answers

What is the main purpose of DNA replication?

  • To create RNA from DNA strands
  • To translate genetic information into proteins
  • To produce new genetic information for the offspring
  • To generate an identical copy of genetic information for daughter cells (correct)

    • Which bases are involved in the AT/GC rule during DNA replication?

  • Adenine, Thymine, Uracil, Cytosine
  • Adenine, Uracil, Guanine, Cytosine
  • Adenine, Uracil, Guanine, Thymine
  • Adenine, Thymine, Guanine, Cytosine (correct)

    • What is the significance of the antiparallel alignment in DNA strands during replication?

  • It regulates the expression of genes
  • It prevents DNA from unraveling
  • It allows for complementary base pairing (correct)
  • It facilitates RNA production

    • Which type of bases form purines and pyrimidines in DNA replication?

    <p>Adenine &amp; Guanine; Cytosine, Uracil &amp; Thymine</p> Signup and view all the answers

    What is the process of copying genetic materials from the original DNA strands called?

    <p>DNA replication</p> Signup and view all the answers

    When does DNA replication occur in eukaryotic cell cycle?

    <p>S phase</p> Signup and view all the answers

    Which protein is responsible for breaking the hydrogen bond between the two DNA strands during DNA replication?

    <p>DnaB</p> Signup and view all the answers

    What is the name of the site where DNA replication starts in prokaryotes?

    <p>OriC site</p> Signup and view all the answers

    Which molecule is NOT involved in the initiation step of DNA replication?

    <p>RNA polymerase</p> Signup and view all the answers

    What is the function of DnaA protein in DNA replication initiation step?

    <p>Separating the double helix strand</p> Signup and view all the answers

    Which characteristic function of various DNA polymerases is NOT mentioned in the learning outcomes?

    <p>Synthesizing RNA primers</p> Signup and view all the answers

    In which direction does DNA helicase move along the DNA during replication fork formation?

    <p>$5' \to 3'$</p> Signup and view all the answers

    How many types of DNA sequences are found within OriC in prokaryotes?

    <p>3</p> Signup and view all the answers

    Which molecule recognizes the AT-rich region and DnaA box sequences at the origin of replication in prokaryotes?

    <p>$DnaA$ protein</p> Signup and view all the answers

    'The process of copying genetic materials from the original DNA strands is called?' is an example of a:

    <p>Knowledge question.</p> Signup and view all the answers

    What is the basis for inheritance according to the provided text?

    <p>DNA replication.</p> Signup and view all the answers

    Which enzyme is responsible for the synthesis of complementary DNA (cDNA) from an RNA template?

    <p>Reverse transcriptase</p> Signup and view all the answers

    What is the main function of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the context of HIV treatment?

    <p>Inhibit the activity of reverse transcriptase enzyme</p> Signup and view all the answers

    In the context of reverse transcription, what is the significance of integrating viral DNA (cDNA) into host DNA?

    <p>To create a provirus for long-term persistence</p> Signup and view all the answers

    Which type of virus is HIV classified as?

    <p>Retrovirus</p> Signup and view all the answers

    What is the role of viral protease in the life cycle of HIV?

    <p>Packaging and releasing viral RNA from the host cell</p> Signup and view all the answers

    Which enzyme is essential for the reverse transcription of HIV?

    <p>Reverse transcriptase</p> Signup and view all the answers

    What is the significance of reverse transcription in the replication cycle of HIV?

    <p>It enables the virus to integrate into the host genome</p> Signup and view all the answers

    Which class of drugs targets reverse transcriptase as a key component of their mechanism of action?

    <p>(NRTIs) Nucleoside Reverse Transcriptase Inhibitors</p> Signup and view all the answers

    What role does integrase play in the replication cycle of HIV?

    <p>Integrating viral DNA into host DNA</p> Signup and view all the answers

    What is the primary target of Human Immunodeficiency Virus (HIV) infection?

    <p>T Helper cells (CD4+)</p> Signup and view all the answers

    What is the role of viral integrase in the replication cycle of HIV?

    <p>Inserting viral DNA into the host’s genome</p> Signup and view all the answers

    What is the main function of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the context of HIV treatment?

    <p>Preventing the synthesis of viral DNA from an RNA template</p> Signup and view all the answers

    What enzyme is essential for the reverse transcription of HIV?

    <p>Reverse transcriptase</p> Signup and view all the answers

    Which molecule recognizes the AT-rich region and DnaA box sequences at the origin of replication in prokaryotes?

    <p>DnaA protein</p> Signup and view all the answers

    Which characteristic function of various DNA polymerases is NOT mentioned in the learning outcomes?

    <p>Synthesizing the complementary DNA from an RNA template</p> Signup and view all the answers

    When does DNA replication occur in eukaryotic cell cycle?

    <p>S phase</p> Signup and view all the answers

    What is the primary target of Human Immunodeficiency Virus (HIV) infection?

    <p>T helper cells (CD4+ cells)</p> Signup and view all the answers

    What is the significance of integrating viral DNA (cDNA) into host DNA in the context of reverse transcription?

    <p>It allows HIV to avoid detection by the immune system and persist in the host</p> Signup and view all the answers

    What is the main purpose of DNA replication?

    <p>Ensuring accurate transmission of genetic information to daughter cells</p> Signup and view all the answers

    What bases are involved in the AT/GC rule during DNA replication?

    <p>Cytosine and thymine</p> Signup and view all the answers

    What enzyme is responsible for breaking the hydrogen bond between two DNA strands during DNA replication?

    <p>DNA helicase</p> Signup and view all the answers

    What type of virus is HIV classified as?

    <p>Retrovirus</p> Signup and view all the answers

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