MM6113 Molecular Medicine: Reverse Transcription Quiz
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Questions and Answers

What is the main purpose of DNA replication?

  • To create RNA from DNA strands
  • To translate genetic information into proteins
  • To produce new genetic information for the offspring
  • To generate an identical copy of genetic information for daughter cells (correct)

Which bases are involved in the AT/GC rule during DNA replication?

  • Adenine, Thymine, Uracil, Cytosine
  • Adenine, Uracil, Guanine, Cytosine
  • Adenine, Uracil, Guanine, Thymine
  • Adenine, Thymine, Guanine, Cytosine (correct)

What is the significance of the antiparallel alignment in DNA strands during replication?

  • It regulates the expression of genes
  • It prevents DNA from unraveling
  • It allows for complementary base pairing (correct)
  • It facilitates RNA production

Which type of bases form purines and pyrimidines in DNA replication?

<p>Adenine &amp; Guanine; Cytosine, Uracil &amp; Thymine (A)</p> Signup and view all the answers

What is the process of copying genetic materials from the original DNA strands called?

<p>DNA replication (A)</p> Signup and view all the answers

When does DNA replication occur in eukaryotic cell cycle?

<p>S phase (B)</p> Signup and view all the answers

Which protein is responsible for breaking the hydrogen bond between the two DNA strands during DNA replication?

<p>DnaB (A)</p> Signup and view all the answers

What is the name of the site where DNA replication starts in prokaryotes?

<p>OriC site (D)</p> Signup and view all the answers

Which molecule is NOT involved in the initiation step of DNA replication?

<p>RNA polymerase (C)</p> Signup and view all the answers

What is the function of DnaA protein in DNA replication initiation step?

<p>Separating the double helix strand (D)</p> Signup and view all the answers

Which characteristic function of various DNA polymerases is NOT mentioned in the learning outcomes?

<p>Synthesizing RNA primers (D)</p> Signup and view all the answers

In which direction does DNA helicase move along the DNA during replication fork formation?

<p>$5' \to 3'$ (D)</p> Signup and view all the answers

How many types of DNA sequences are found within OriC in prokaryotes?

<p>3 (C)</p> Signup and view all the answers

Which molecule recognizes the AT-rich region and DnaA box sequences at the origin of replication in prokaryotes?

<p>$DnaA$ protein (A)</p> Signup and view all the answers

'The process of copying genetic materials from the original DNA strands is called?' is an example of a:

<p>Knowledge question. (D)</p> Signup and view all the answers

What is the basis for inheritance according to the provided text?

<p>DNA replication. (D)</p> Signup and view all the answers

Which enzyme is responsible for the synthesis of complementary DNA (cDNA) from an RNA template?

<p>Reverse transcriptase (D)</p> Signup and view all the answers

What is the main function of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the context of HIV treatment?

<p>Inhibit the activity of reverse transcriptase enzyme (B)</p> Signup and view all the answers

In the context of reverse transcription, what is the significance of integrating viral DNA (cDNA) into host DNA?

<p>To create a provirus for long-term persistence (D)</p> Signup and view all the answers

Which type of virus is HIV classified as?

<p>Retrovirus (C)</p> Signup and view all the answers

What is the role of viral protease in the life cycle of HIV?

<p>Packaging and releasing viral RNA from the host cell (C)</p> Signup and view all the answers

Which enzyme is essential for the reverse transcription of HIV?

<p>Reverse transcriptase (C)</p> Signup and view all the answers

What is the significance of reverse transcription in the replication cycle of HIV?

<p>It enables the virus to integrate into the host genome (C)</p> Signup and view all the answers

Which class of drugs targets reverse transcriptase as a key component of their mechanism of action?

<p>(NRTIs) Nucleoside Reverse Transcriptase Inhibitors (D)</p> Signup and view all the answers

What role does integrase play in the replication cycle of HIV?

<p>Integrating viral DNA into host DNA (D)</p> Signup and view all the answers

What is the primary target of Human Immunodeficiency Virus (HIV) infection?

<p>T Helper cells (CD4+) (B)</p> Signup and view all the answers

What is the role of viral integrase in the replication cycle of HIV?

<p>Inserting viral DNA into the host’s genome (A)</p> Signup and view all the answers

What is the main function of non-nucleoside reverse transcriptase inhibitors (NNRTIs) in the context of HIV treatment?

<p>Preventing the synthesis of viral DNA from an RNA template (B)</p> Signup and view all the answers

What enzyme is essential for the reverse transcription of HIV?

<p>Reverse transcriptase (B)</p> Signup and view all the answers

Which molecule recognizes the AT-rich region and DnaA box sequences at the origin of replication in prokaryotes?

<p>DnaA protein (A)</p> Signup and view all the answers

Which characteristic function of various DNA polymerases is NOT mentioned in the learning outcomes?

<p>Synthesizing the complementary DNA from an RNA template (B)</p> Signup and view all the answers

When does DNA replication occur in eukaryotic cell cycle?

<p>S phase (C)</p> Signup and view all the answers

What is the primary target of Human Immunodeficiency Virus (HIV) infection?

<p>T helper cells (CD4+ cells) (D)</p> Signup and view all the answers

What is the significance of integrating viral DNA (cDNA) into host DNA in the context of reverse transcription?

<p>It allows HIV to avoid detection by the immune system and persist in the host (A)</p> Signup and view all the answers

What is the main purpose of DNA replication?

<p>Ensuring accurate transmission of genetic information to daughter cells (C)</p> Signup and view all the answers

What bases are involved in the AT/GC rule during DNA replication?

<p>Cytosine and thymine (D)</p> Signup and view all the answers

What enzyme is responsible for breaking the hydrogen bond between two DNA strands during DNA replication?

<p>DNA helicase (C)</p> Signup and view all the answers

What type of virus is HIV classified as?

<p>Retrovirus (D)</p> Signup and view all the answers

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