MLS Review Study Plan
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Questions and Answers

What is the recommended approach to reviewing content areas before the examination?

  • Study your weakest subject first, then progress to your strongest.
  • Study your strongest subject first, then progress to your weakest. (correct)
  • Only review your strongest subject to boost confidence.
  • Study all subjects simultaneously to save time.

    • What should you do while using this review book to test your knowledge of the content area?

  • Only read the explanations for the questions you answered correctly.
  • Use online resources instead of the book's explanations.
  • Read the explanations for each question, regardless of whether you answered it correctly or not. (correct)
  • Skip the explanations and only focus on answering the questions.

    • What should you do with the information you did not know while reviewing the content area?

  • Skip it and focus on the information you already know.
  • Try to memorize it without understanding the concept.
  • Highlight it and review it before answering the questions in the book a second time. (correct)
  • Move on to the next question and come back to it later.

    • What is the purpose of taking the comprehensive examination included in the book?

    <p>To evaluate your performance by both subject and taxonomy.</p> Signup and view all the answers

    What should you do if you score lower in a particular subject area?

    <p>Devote more time to studying the subject area where you scored lower.</p> Signup and view all the answers

    What is recommended for recalling information from charts and tables?

    <p>Make note cards with charts and tables.</p> Signup and view all the answers

    What should you do in your third round of study?

    <p>Plan your third round of study so that you end with your weakest subject.</p> Signup and view all the answers

    What should you do after completing the third round of study?

    <p>Take online examinations to test your knowledge.</p> Signup and view all the answers

    What is the characteristic of Döhle bodies in polymorphonuclear neutrophils (PMNs)?

    <p>They are oval and light blue</p> Signup and view all the answers

    Which of the following enzymes is NOT contained in the primary granules of neutrophils?

    <p>Lactoferrin</p> Signup and view all the answers

    What is the mean relative lymphocyte percentage for a 1-year-old child?

    <p>61%</p> Signup and view all the answers

    Which of the following is NOT a qualitative and quantitative neutrophil change noted in response to infection?

    <p>Nuclear hyposegmentation</p> Signup and view all the answers

    What is the absolute neutrophil count that indicates neutropenia?

    <p>Less than 1.5 × 109/L</p> Signup and view all the answers

    What is the morphological characteristic associated with Chédiak–Higashi syndrome?

    <p>Giant lysosomal granules</p> Signup and view all the answers

    What condition must Pelger–Huët anomaly be differentiated from?

    <p>May–Hegglin anomaly</p> Signup and view all the answers

    What type of granules contain lactoferrin and collagenase?

    <p>Secondary granules</p> Signup and view all the answers

    What is the normal physiological response to anemia?

    <p>An increase in the kidney’s production of erythropoietin</p> Signup and view all the answers

    What is a characteristic of marrow failure due to leukemia?

    <p>Anemia, thrombocytopenia, and granulocytopenia</p> Signup and view all the answers

    What type of acute leukemia is characterized by monoblasts, promonocytes, and monocytes?

    <p>Acute monocytic leukemia</p> Signup and view all the answers

    At what age does ALL (Acute Lymphoblastic Leukemia) occur with the highest frequency?

    <p>1-15 years</p> Signup and view all the answers

    Which type of acute leukemia is most often associated with disseminated intravascular coagulation (DIC)?

    <p>Acute promyelocytic leukemia (PML)</p> Signup and view all the answers

    What is the significance of an M:E ratio of 10:1?

    <p>It is seen in leukemia</p> Signup and view all the answers

    What is a characteristic of Auer rods?

    <p>They are composed of azurophilic granules</p> Signup and view all the answers

    What is the incidence of acute monocytic leukemia among all acute leukemias?

    <p>1% to 8%</p> Signup and view all the answers

    What type of tubes can be used to draw blood without affecting the ESR?

    <p>Sodium citrate and EDTA tubes</p> Signup and view all the answers

    What is the term for anemia characterized by normal erythrocyte size and normal hemoglobin concentration?

    <p>Normocytic normochromic anemia</p> Signup and view all the answers

    What is the most common staining method used to stain and manually count reticulocytes?

    <p>Supravital staining</p> Signup and view all the answers

    What is the principle behind the Coulter principle for counting of cells?

    <p>Isotonic solutions conduct electricity better than cells do</p> Signup and view all the answers

    Why is a correction necessary for WBC counts when NRBCs are seen on the peripheral blood smear?

    <p>NRBCs are counted as leukocytes</p> Signup and view all the answers

    What type of anemia is characterized by anisocytosis and poikilocytosis?

    <p>Microcytic anemia</p> Signup and view all the answers

    What would an increased RDW correlate with?

    <p>Anisocytosis</p> Signup and view all the answers

    What factor does not influence the erythrocyte sedimentation rate (ESR)?

    <p>Blood drawn into a sodium citrate tube</p> Signup and view all the answers

    What is the term for the bluish tinge of immature erythrocytes in peripheral blood?

    <p>Polychromasia</p> Signup and view all the answers

    What is the formula to calculate the mean cell hemoglobin concentration (MCHC)?

    <p>Hgb / Hct</p> Signup and view all the answers

    What is the purpose of a 1:10 dilution in a manual WBC count?

    <p>To decrease the number of cells to be counted</p> Signup and view all the answers

    What type of cell is stained with Prussian blue to reveal iron granules?

    <p>Siderocyte</p> Signup and view all the answers

    What test is most likely to be erroneous if a 7.0-mL EDTA tube is received with only 2.0 mL of blood?

    <p>Hct</p> Signup and view all the answers

    What type of phagocytic cells produce lysozymes that are bacteriocidal?

    <p>Neutrophils</p> Signup and view all the answers

    What is the formula to calculate the RBC count from a manual count?

    <p>Total cells counted / (dilution x area counted)</p> Signup and view all the answers

    What is the unit of measurement for Hemoglobin (Hgb) in the calculation of MCHC?

    <p>g/dL</p> Signup and view all the answers

    Study Notes

    Study Plan for MLS Review

    • Create a study plan to review each content area at least three times
    • Start with the strongest subject and progress to the weakest
    • Review class notes first, then use the review book to test knowledge
    • Read explanations for each question, regardless of whether answered correctly or not
    • Highlight unknown information and review before answering questions again
    • Evaluate performance by subject and taxonomy after the second round
    • Devote more time to weak subjects and take note cards with charts and tables to commit to memory

    Test-Taking Skills

    • Make a study plan before the examination
    • Plan to review all material in a few days
    • Practice with questions online to get exposure to many more based on interpreting photomicrographs

    Hematology

    Polychromasia

    • Describes the bluish tinge of immature erythrocytes (reticulocytes) circulating in peripheral blood

    Calculate MCHC

    • Formula: MCHC = Hgb / Hct
    • Example: Hgb = 15 g/dL, Hct = 47 mL/dL, RBC = 4.50 × 10^6/µL
    • Answer: C. 31.9% (0.319)

    Manual WBC Count

    • Formula: Total WBC count = (Total cells counted / Total squares counted) × Dilution factor
    • Example: Total cells counted = 36, Dilution factor = 1:10
    • Answer: D. 8.0 × 10^9/L

    Iron Granules in Erythrocytes

    • When stained with Prussian blue, iron granules in erythrocytes are called siderocytes

    Errors in Laboratory Tests

    • Errors can occur in RBC count, Hgb, Hct, and WBC count due to specimen collection and handling
    • Example: 7.0-mL EDTA tube received with only 2.0 mL of blood
    • Answer: A. RBC count

    Phagocytic Cells

    • Neutrophils produce lysozymes that are bacteriocidal
    • Eosinophils, lymphocytes, and platelets do not produce lysozymes

    Reticulocyte Count

    • Supravital staining is used most frequently to stain and manually count reticulocytes
    • Immunofluorescence, Romanowsky staining, and cytochemical staining are not used for reticulocyte count

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    Create a study plan to review each content area at least three times, starting with the strongest subject and progressing to the weakest. Review class notes, use review books, and evaluate performance by subject and taxonomy.

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