MLS 416: Rh Blood Group System Midterm Quiz

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Questions and Answers

What is the significance of the absence of the D antigen in Rh negative individuals?

  • They have a weaker immune system
  • They have a higher risk of blood disease
  • They lack all Rh antigens
  • They have the C and E antigens (correct)

What was the contribution of Landsteiner and Weiner to the Rh blood group system?

  • Identification of the genetic basis of the Rh system
  • Discovery of the Rh antigen
  • Development of a vaccine against the Rh antigen
  • Demonstration of the presence of Rh antigens in humans (correct)

What was the outcome of injecting Rh monkey cells into guinea pigs and rabbits?

  • The animals produced no immune response
  • The animals developed an allergic reaction
  • The animals produced antibodies against human RBCs (correct)
  • The animals became Rh positive

What is the difference between the anti-Rh antibody in Rhesus monkey cells and human RBCs?

<p>The antibody is similar but not identical (D)</p> Signup and view all the answers

What is the significance of the Chromosome 6?

<p>It is the location of the Coexpressor (B)</p> Signup and view all the answers

Why did the first pregnancy not trigger an immune response in the mother?

<p>The baby's Rh antigens were not recognized by the mother's immune system (B)</p> Signup and view all the answers

What is the origin of the name 'Rh' in the Rh blood group system?

<p>From the Rhesus monkey (D)</p> Signup and view all the answers

What is the current accepted theory of Rh inheritance?

<p>The Current Rh Genetic Theory (B)</p> Signup and view all the answers

What is unique about the RHD and RHCE genes?

<p>They are closely linked on chromosome 1 (A)</p> Signup and view all the answers

What is the role of RHD gene?

<p>Responsible for producing the D antigen (B)</p> Signup and view all the answers

What is the significance of Levine and Stetson's study?

<p>They linked HDFN to the Rh blood group system (A)</p> Signup and view all the answers

What was the outcome of the blood transfusion in Levine and Stetson's study?

<p>The mother had a haemolytic transfusion reaction (B)</p> Signup and view all the answers

What is the basis for the different antigens found on the red cell?

<p>The alleles RHCE, RHCe, RHcE, Rhce (D)</p> Signup and view all the answers

Why is the Rh blood group system important in blood transfusion?

<p>Because it is responsible for haemolytic transfusion reactions (A)</p> Signup and view all the answers

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