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MLS 416: Rh Blood Group System Midterm Quiz

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MLS 416: Rh Blood Group System Midterm Quiz

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Questions and Answers

What is the significance of the absence of the D antigen in Rh negative individuals?

They have a weaker immune system

They have a higher risk of blood disease

They lack all Rh antigens

They have the C and E antigens (correct)

What was the contribution of Landsteiner and Weiner to the Rh blood group system?

Identification of the genetic basis of the Rh system

Discovery of the Rh antigen

Development of a vaccine against the Rh antigen

Demonstration of the presence of Rh antigens in humans (correct)

What was the outcome of injecting Rh monkey cells into guinea pigs and rabbits?

The animals produced no immune response

The animals developed an allergic reaction

The animals produced antibodies against human RBCs (correct)

The animals became Rh positive

What is the difference between the anti-Rh antibody in Rhesus monkey cells and human RBCs?

The antibody is similar but not identical Signup and view all the answers

What is the significance of the Chromosome 6?

It is the location of the Coexpressor Signup and view all the answers

Why did the first pregnancy not trigger an immune response in the mother?

The baby's Rh antigens were not recognized by the mother's immune system Signup and view all the answers

What is the origin of the name 'Rh' in the Rh blood group system?

From the Rhesus monkey Signup and view all the answers

What is the current accepted theory of Rh inheritance?

The Current Rh Genetic Theory Signup and view all the answers

What is unique about the RHD and RHCE genes?

They are closely linked on chromosome 1 Signup and view all the answers

What is the role of RHD gene?

Responsible for producing the D antigen Signup and view all the answers

What is the significance of Levine and Stetson's study?

They linked HDFN to the Rh blood group system Signup and view all the answers

What was the outcome of the blood transfusion in Levine and Stetson's study?

The mother had a haemolytic transfusion reaction Signup and view all the answers

What is the basis for the different antigens found on the red cell?

The alleles RHCE, RHCe, RHcE, Rhce Signup and view all the answers

Why is the Rh blood group system important in blood transfusion?

Because it is responsible for haemolytic transfusion reactions Signup and view all the answers