14 Questions
What is the significance of the absence of the D antigen in Rh negative individuals?
They have the C and E antigens
What was the contribution of Landsteiner and Weiner to the Rh blood group system?
Demonstration of the presence of Rh antigens in humans
What was the outcome of injecting Rh monkey cells into guinea pigs and rabbits?
The animals produced antibodies against human RBCs
What is the difference between the anti-Rh antibody in Rhesus monkey cells and human RBCs?
The antibody is similar but not identical
What is the significance of the Chromosome 6?
It is the location of the Coexpressor
Why did the first pregnancy not trigger an immune response in the mother?
The baby's Rh antigens were not recognized by the mother's immune system
What is the origin of the name 'Rh' in the Rh blood group system?
From the Rhesus monkey
What is the current accepted theory of Rh inheritance?
The Current Rh Genetic Theory
What is unique about the RHD and RHCE genes?
They are closely linked on chromosome 1
What is the role of RHD gene?
Responsible for producing the D antigen
What is the significance of Levine and Stetson's study?
They linked HDFN to the Rh blood group system
What was the outcome of the blood transfusion in Levine and Stetson's study?
The mother had a haemolytic transfusion reaction
What is the basis for the different antigens found on the red cell?
The alleles RHCE, RHCe, RHcE, Rhce
Why is the Rh blood group system important in blood transfusion?
Because it is responsible for haemolytic transfusion reactions
This quiz covers the Rh blood group system, its inheritance, and current genetic theory. It's designed for students of MLS 416, a course in immunohematology. The quiz tests knowledge of the Rh blood group, its relation to the LW group, and the experiments on Rhesus monkeys.
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