Questions and Answers
What is the first stage of mitosis?
Prophase
What is the second stage of mitosis?
Prometaphase
What occurs during metaphase?
Sister chromatids line up at the metaphase plate.
What happens during anaphase?
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What is the fifth step in mitosis?
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What is the sixth and final step of mitosis?
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The correct order of mitosis is: prophase, ______, metaphase, anaphase, telophase, and cytokinesis.
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What does the following passage describe?: The kinetochores appear at the centromeres, the mitotic spindle microtubules attach to kinetochores, and the centrosomes move toward opposite poles.
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What are the correct sequence of events in mitosis?
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What is mitosis?
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Study Notes
Mitosis Overview
- Mitosis is a type of eukaryotic cell division responsible for the separation of the cell nucleus.
- Mitosis comprises several phases: prophase, prometaphase, metaphase, anaphase, telophase, and cytokinesis.
Prophase
- Chromosomes condense and become visible as discrete structures.
- Spindle fibers emerge from centrosomes.
- The nuclear envelope begins to break down, and the nucleolus disappears.
Prometaphase
- Chromosomes continue to condense.
- Kinetochores form at the centromeres of chromosomes.
- Mitotic spindle microtubules attach to the kinetochores.
- Centrosomes move toward opposite poles of the cell.
Metaphase
- The mitotic spindle is fully developed, with centrosomes at opposing poles.
- Chromosomes align at the metaphase plate.
- Each sister chromatid is attached to spindle fibers from opposite poles, ensuring proper separation.
Anaphase
- Cohesin proteins that hold sister chromatids together break down.
- Sister chromatids are pulled toward opposite poles, now referred to as chromosomes.
- Non-kinetochore spindle fibers elongate, which stretches the cell.
Telophase
- Chromosomes arrive at opposite poles and begin to decondense.
- Nuclear envelope material re-forms around each set of chromosomes.
- The mitotic spindle disassembles.
Cytokinesis
- The final step of mitosis, involving the division of cytoplasm.
- In animal cells, a cleavage furrow forms to separate daughter cells.
- In plant cells, a cell plate forms to create a barrier between daughter cells.
Key Questions
- The correct order of mitosis stages: prophase, prometaphase, metaphase, anaphase, telophase, cytokinesis.
- Prometaphase is characterized by the appearance of kinetochores, attachment of mitotic spindle microtubules, and movement of centrosomes.
- During anaphase, sister chromatids are pulled toward opposite poles of the cell.
- Key events include the attachment of kinetochores to the mitotic spindle, alignment at the metaphase plate, separation of sister chromatids, and reformation of the nucleus as the cell divides.
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Test your understanding of the stages of mitosis with these flashcards. Each card highlights a specific phase, detailing the key events and characteristics. Perfect for biology students looking to reinforce their knowledge of cell division.