Podcast
Play an AI-generated podcast conversation about this lesson
Questions and Answers
What is the main role of the Malate Aspartate Shuttle in mitochondrial transport systems?
What is the main role of the Malate Aspartate Shuttle in mitochondrial transport systems?
- Providing substrates for ATP synthase
- Exporting ATP to the cytosol
- Transferring electrons from cytosolic NADH to mitochondrial NAD+ (correct)
- Blocking the proton channel of ATP Synthase
What is the primary function of Uncouplers in electron transport and oxidative phosphorylation?
What is the primary function of Uncouplers in electron transport and oxidative phosphorylation?
- Allow O2 consumption without ATP synthesis (correct)
- Transfer electrons from NADH to NAD+
- Block electron transport
- Enhance ATP synthesis
How do inhibitors like Cyanide affect the electron transport chain (ETC)?
How do inhibitors like Cyanide affect the electron transport chain (ETC)?
- Promote NADH production
- Block electron transport & ATP synthesis (correct)
- Enhance O2 consumption
- Increase ATP synthesis
What is the consequence of Oligomycin blocking the proton channel of ATP Synthase?
What is the consequence of Oligomycin blocking the proton channel of ATP Synthase?
Signup and view all the answers
In what conditions do ATP yields from glucose differ slightly between liver and muscle?
In what conditions do ATP yields from glucose differ slightly between liver and muscle?
Signup and view all the answers
What is the impact of diet aid dinitrophenol (DNP) on electron transport and ATP synthesis?
What is the impact of diet aid dinitrophenol (DNP) on electron transport and ATP synthesis?
Signup and view all the answers
Flashcards are hidden until you start studying
Study Notes
Mitochondrial Transport Systems
- Phosphate and ATP/ADP translocases provide substrates for ATP synthase and export ATP.
- The Malate Aspartate Shuttle moves electrons from cytosolic NADH to mitochondrial NAD+.
- The Glycerol-3-Phosphate Shuttle transfers electrons from cytosolic NADH to mitochondrial NAD+.
ATP Yield and Regulation
- ATP yields from glucose differ slightly in liver and muscle in aerobic conditions.
- The rate of respiration is dependent on concentrations of substrates and products.
Inhibitors of Electron Transport and ATP Synthesis
- Cyanide blocks electron transport and ATP synthesis.
- Oligomycin blocks the proton channel of ATP Synthase.
- ATP synthesis requires electron transport, and electron transport requires ATP synthesis.
Uncouplers of Electron Transport and ATP Synthesis
- Electron transport and ATP synthesis can be uncoupled.
- Uncoupling occurs in brown fat and allows non-shivering thermogenesis.
- Dinitrophenol (DNP) is a diet aid that uncouples electron transport and ATP synthesis.
- Uncoupling agents allow O2 consumption to occur without ATP synthesis.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
