Questions and Answers
What is the trade name for Mirtazapine?
Mirtazapine falls under the class of __________.
Tetracyclic antidepressants
What is the primary indication for Mirtazapine?
Major depressive disorder
What is the mechanism of action (MOA) of Mirtazapine?
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What is the safe dosage for Mirtazapine?
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Which of the following is a contraindication for Mirtazapine?
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Name one precaution associated with Mirtazapine.
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Match the following adverse effects with Mirtazapine:
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What should you assess when a patient is on Mirtazapine?
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Patients should double the dose if they missed a dose of Mirtazapine.
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Study Notes
Mirtazapine Overview
- Trade Name: Remeron
Classification
- Pregnancy Category: C
- Therapeutic Class: Antidepressant
- Pharmacologic Class: Tetracyclic antidepressants
Indications
- Primarily prescribed for Major Depressive Disorder.
Mechanism of Action (MOA)
- Enhances the effects of norepinephrine and serotonin, contributing to its antidepressant properties.
Dosage
- Typical safe dosage is 15 mg daily.
Contraindications
- Not suitable for individuals with hypersensitivity or those using MAO inhibitors or similar medications.
Precautions
- Caution for patients with:
- A history of seizures or suicide attempts.
- Increased suicide ideation risk, especially during initial treatment or dose changes.
- Previous mania or hypomania.
- Liver or kidney impairments.
- Angle-closure glaucoma.
- Increased sensitivity to central nervous system effects and risk of oversedation.
Adverse Effects
- Potential serious conditions include:
- Neuroleptic malignant syndrome
- Suicidal thoughts
- Agranulocytosis
- Serotonin syndrome
- Common side effects involve:
- Drowsiness, constipation, weight gain
- Abnormal dreams, agitation, anxiety, confusion
- Dizziness, malaise, weakness, respiratory issues (dyspnea, cough)
- Dry mouth, increased appetite, abdominal pain
- Other symptoms: hypertension, pruritus, rash, increased thirst, hypercholesterolemia, and more.
Assessment
- Important evaluations include:
- Monitoring mental status and vital signs.
- Observing for changes in behavior, weight, and BMI.
- Tracking seizure activity.
Patient Teaching
- Instruct patients on medication adherence:
- Skip missed doses rather than doubling.
- Warn against abrupt discontinuation.
- Inform about orthostatic hypertension effects.
- Advise to avoid other CNS depressants.
- Notify healthcare provider prior to any surgical procedures or new treatments.
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Description
Test your knowledge about Mirtazapine with these flashcards. Learn about its trade names, classifications, indications, and mechanisms of action. Perfect for students or healthcare professionals looking to brush up on their pharmacology.
