Mineralization in Hard Tissues
32 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the chemical formula for the mineral component of mineralization?

  • H2O
  • NaCl
  • C10H12O6
  • Ca10(PO4)6(OH)2 (correct)

    • What substances are involved in mineralization?

  • Mineral and organic matrix (correct)
  • Water and air
  • Proteins and lipids
  • Carbohydrates and vitamins

    • What is the main reason why precipitation of ions occurs in any solution during the process of mineralization?

  • Energy is needed in the process of crystal formation (correct)
  • The high concentration of water
  • The absence of inhibitors in tissue fluid
  • The presence of proteoglycans

    • What is the role of Mg in hydroxyapatite crystals during mineralization?

    <p>It inhibits crystal growth</p> Signup and view all the answers

    Which ion substitution reduces the crystal solubility in hydroxyapatite during mineralization?

    <p>F ↔ OH</p> Signup and view all the answers

    What is the ground substance in the organic matrix of mineralization?

    <p>Proteoglycans and glycoproteins</p> Signup and view all the answers

    What are substances which reduce the amount of energy required for precipitation of substances called?

    <p>Nucleating substances</p> Signup and view all the answers

    Which theory discusses the role of collagen as a nucleating agent for mineralization?

    <p>Matrix vesicle theory</p> Signup and view all the answers

    What is the process of precipitation of mineral salts in the tissue fluid during mineralization called?

    <p>Homogeneous nucleation</p> Signup and view all the answers

    What is the function of matrix vesicles in mineral precipitation?

    <p>Act as nucleating agents</p> Signup and view all the answers

    What is the main role of alkaline phosphatase in mineralization?

    <p>Cleavage of pyrophosphate</p> Signup and view all the answers

    Which type of nucleation involves the presence of a nucleating agent?

    <p>Heterogeneous nucleation</p> Signup and view all the answers

    What is the criticism of the booster theory in mineralization?

    <p>Alkaline phosphatase is found in other tissues which do not mineralize</p> Signup and view all the answers

    What role do non-collagenous proteins play in mineralization?

    <p>Act as nucleating agents</p> Signup and view all the answers

    What do matrix vesicles contain that can mediate the influx of calcium into them?

    <p>Annexin V</p> Signup and view all the answers

    What is the process that involves a local increase in the concentration of inorganic ions, leading to sufficient ionic clusters for crystallites to form?

    <p>Homogeneous nucleation</p> Signup and view all the answers

    What is the primary mineral component involved in mineralization?

    <p>Biologic apatite</p> Signup and view all the answers

    What are the two substances involved in mineralization?

    <p>Mineral and organic matrix</p> Signup and view all the answers

    What is the role of Mg in hydroxyapatite crystals during mineralization?

    <p>It inhibits crystal growth</p> Signup and view all the answers

    What is the ground substance in the organic matrix of mineralization?

    <p>Proteoglycans</p> Signup and view all the answers

    What hinders the precipitation of mineral salts and growth of crystals in tissue fluid?

    <p>Presence of macromolecules</p> Signup and view all the answers

    What is the chemical formula for the mineral component involved in mineralization?

    <p>$Ca10(PO4)6(OH)2$</p> Signup and view all the answers

    What is the process of precipitation of mineral salts in the tissue fluid during mineralization called?

    <p>Nucleation</p> Signup and view all the answers

    What is the main role of alkaline phosphatase in mineralization?

    <p>Hydrolyze organic phosphate and provide inorganic phosphate</p> Signup and view all the answers

    Which type of nucleation involves a local increase in the concentration of inorganic ions, leading to sufficient ionic clusters for crystallites to form?

    <p>Homogeneous nucleation</p> Signup and view all the answers

    What role do non-collagenous proteins play in mineralization?

    <p>Act as nucleating agent</p> Signup and view all the answers

    What substances reduce the amount of energy required for precipitation of substances?

    <p>Nucleating substances</p> Signup and view all the answers

    What is the criticism of the booster theory in mineralization?

    <p>Alk P + Inorganic Phosphate+ Calcium is not enough for mineralization</p> Signup and view all the answers

    What do matrix vesicles contain that can mediate the influx of calcium into them?

    <p>Annexin V</p> Signup and view all the answers

    What is the ground substance in the organic matrix of mineralization?

    <p>Non-collagenous proteins</p> Signup and view all the answers

    What is the reason for removal or inhibition of macromolecules that inhibit precipitation of salts during mineral deposition?

    <p>'Reduction of energy required for precipitation'</p> Signup and view all the answers

    What is the process that involves a local increase in the concentration of inorganic ions, leading to sufficient ionic clusters for crystallites to form?

    <p>Homogeneous nucleation</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser