Microtubules
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Questions and Answers

Which cellular structures have a major structural role in eukaryotic cilia and flagella?

  • Microtubules (correct)
  • Intermediate filaments
  • Actin filaments
  • Nucleosomes

    • What is the main function of flagella in cells?

  • To move cells in an aqueous environment (correct)
  • To move fluid around a cell
  • To hold cells sheets together
  • To provide mechanical stability to cells

    • What is the main function of cilia in cells?

  • To move cells in an aqueous environment
  • To hold cells sheets together
  • To move fluid around a cell (correct)
  • To provide mechanical stability to cells

    • Which drug blocks microtubules and is used in cancer therapy?

    <p>Taxol (Paclitaxel)</p> Signup and view all the answers

    Which cellular structures are associated with cell-cell junctions and strengthening cells?

    <p>Intermediate filaments</p> Signup and view all the answers

    Which cellular structures form a protective cage for the cell's DNA?

    <p>Intermediate filaments</p> Signup and view all the answers

    Which cellular structures help nerve cells extend long and robust axons?

    <p>Intermediate filaments</p> Signup and view all the answers

    Which protein travels towards the (+) end of the microtubule?

    <p>Kinesin</p> Signup and view all the answers

    What causes the microtubule to shrink?

    <p>GTP hydrolysis</p> Signup and view all the answers

    What is the major microtubule organizing center (MTOC) in animal cells?

    <p>Centrosome</p> Signup and view all the answers

    Which type of microtubule is responsible for aligning and segregating the chromosomes during cell division?

    <p>Bipolar mitotic spindle</p> Signup and view all the answers

    What is the function of MAPs (Microtubule-associated proteins)?

    <p>Move organelles and vesicles within the cell</p> Signup and view all the answers

    Which protein transports intracellular cargos towards the (-) end of the microtubule?

    <p>Dynein</p> Signup and view all the answers

    What can selectively stabilize the microtubules and polarize a cell?

    <p>MAPs</p> Signup and view all the answers

    Which proteins make up the tubulin subunit?

    <p>Alpha-tubulin and beta-tubulin</p> Signup and view all the answers

    What is the function of microtubules?

    <p>Cellular transport</p> Signup and view all the answers

    What is the role of GTP in microtubules?

    <p>GTP is bound to alpha-tubulin and is not hydrolyzed nor exchanged</p> Signup and view all the answers

    How are microtubules structured?

    <p>Hollow cylindrical structures built from protofilaments</p> Signup and view all the answers

    What is dynamic instability in microtubules?

    <p>The coexistence of assembly and disassembly at the ends of a microtubule</p> Signup and view all the answers

    Which proteins are associated with microtubules?

    <p>Microtubule-associated proteins (MAPs)</p> Signup and view all the answers

    What are some examples of structures that contain microtubules?

    <p>Cilia and flagella</p> Signup and view all the answers

    Which protein structure is the central building block of intermediate filaments?

    <p>Coiled-coil</p> Signup and view all the answers

    Which type of cells produce keratin filaments in the epidermis?

    <p>Keratinocytes</p> Signup and view all the answers

    What is the clinical usefulness of the diversity of keratins?

    <p>Diagnosis of carcinoma</p> Signup and view all the answers

    Which genetic diseases can be caused by mutation in keratin genes?

    <p>Epidermolysis bullosa simplex and pachyonychia congenita</p> Signup and view all the answers

    What is the main effect of mutation in keratin genes in epidermolysis bullosa simplex (EBS)?

    <p>Blistering of the epidermis</p> Signup and view all the answers

    Which intermediate filament is responsible for the mechanical stability of the cell nucleus?

    <p>Lamin</p> Signup and view all the answers

    What is the function of neurofilaments in vertebrate neurons?

    <p>Provide strength and stability to the axon</p> Signup and view all the answers

    What is the diameter of microfilaments?

    <p>7-8 nm</p> Signup and view all the answers

    Which protein subunits make up microtubules?

    <p>Tubulin</p> Signup and view all the answers

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