Microscopic Anatomy of Skeletal Muscle Fiber Quiz
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Questions and Answers

What is the dominant tissue in the heart and in the walls of other hollow organs?

  • Nervous tissue
  • Muscle tissue (correct)
  • Connective tissue
  • Epithelial tissue

    • What distinguishes muscles from other tissues?

  • Ability to produce hormones
  • Ability to conduct electrical impulses
  • Ability to convert chemical energy into mechanical energy (correct)
  • Ability to store and release energy

    • Where does cardiac muscle tissue occur?

  • In both smooth and skeletal muscles
  • Only in the walls of other hollow organs
  • Only in the heart (correct)
  • In both the heart and skeletal muscles

    • What is the Latin origin of the word 'muscle'?

    <p>Nius meaning 'little mouse'</p> Signup and view all the answers

    What type of muscle is not striated and is also not subject to voluntary control?

    <p>Smooth muscle</p> Signup and view all the answers

    Where is smooth muscle found?

    <p>In hollow visceral organs</p> Signup and view all the answers

    What type of muscle cells are striated and involuntary?

    <p>Cardiac muscle</p> Signup and view all the answers

    Which muscle type contracts at a steady rate but can speed up with neural controls?

    <p>Cardiac muscle</p> Signup and view all the answers

    What is the function of smooth muscle?

    <p>Regulating fluid flow</p> Signup and view all the answers

    What surrounds each individual muscle fiber?

    <p>Endomysium</p> Signup and view all the answers

    What is the dense irregular connective tissue that surrounds the whole muscle called?

    <p>Epimysium</p> Signup and view all the answers

    What controls the activity of skeletal muscle fibers?

    <p>Nerve endings</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Connective tissue sheaths</p> Signup and view all the answers

    What transmits the pulling force from muscle fibers to the bone to be moved?

    <p>Connective tissue sheaths</p> Signup and view all the answers

    Where do most skeletal muscles attach to bones?

    <p>At least two places</p> Signup and view all the answers

    What is the connective tissue that surrounds each fascicle?

    <p>Perimysium</p> Signup and view all the answers

    What are tendons mostly composed of?

    <p>Collagen fibers</p> Signup and view all the answers

    What is a muscle fiber?

    <p>A single muscle cell</p> Signup and view all the answers

    What are myofibrils?

    <p>Rodlike contractile elements</p> Signup and view all the answers

    What is a sarcomere?

    <p>The contractile unit of a muscle</p> Signup and view all the answers

    What produces muscle shortening?

    <p>Sliding of thin filaments past thick filaments</p> Signup and view all the answers

    What is the average length of a sarcomere?

    <p>2 µm</p> Signup and view all the answers

    What type of filaments are myosin filaments?

    <p>Contractile</p> Signup and view all the answers

    What type of filaments are actin filaments?

    <p>Non-contractile</p> Signup and view all the answers

    What is the most common type of muscle attachment?

    <p>Indirect attachment</p> Signup and view all the answers

    What is the connective tissue that surrounds the entire muscle?

    <p>Epimysium</p> Signup and view all the answers

    What is the function of a fascicle?

    <p>To segregate muscle cells from the rest of the muscle</p> Signup and view all the answers

    What is the inheritance pattern of muscular dystrophy?

    <p>X-linked recessive</p> Signup and view all the answers

    What is the approximate occurrence of Duchenne muscular dystrophy (DMD) in male births?

    <p>1 in 3600 births</p> Signup and view all the answers

    What are the common symptoms of Duchenne muscular dystrophy (DMD) in affected boys?

    <p>Muscle weakness, clumsiness, and falls</p> Signup and view all the answers

    Which protein stabilizes the sarcolemma and links cytoskeleton to the extracellular matrix?

    <p>Dystrophin</p> Signup and view all the answers

    What is the function of titin in muscle cells?

    <p>Maintaining muscle cell organization and resisting excessive stretching</p> Signup and view all the answers

    What structures regulate muscle contraction in skeletal muscle fibers?

    <p>Sarcoplasmic reticulum and T tubules</p> Signup and view all the answers

    What is the role of myosin heads during muscle contraction?

    <p>Binding to the myosin-binding sites on actin</p> Signup and view all the answers

    Which components control myosin-actin interactions during muscle contraction?

    <p>Troponin and tropomyosin</p> Signup and view all the answers

    What happens to the fragile sarcolemma during muscle contraction in DMD?

    <p>It tears, leading to muscle damage</p> Signup and view all the answers

    What is the aim of current treatments for DMD?

    <p>Preventing deformities and maintaining mobility</p> Signup and view all the answers

    In DMD, the progression of muscle weakness occurs from extremities to which parts of the body?

    <p>Head and neck</p> Signup and view all the answers

    With supportive care, how long can DMD patients typically live?

    <p>Into their 30s and beyond</p> Signup and view all the answers

    What is the functional unit of a myofibril responsible for the banding pattern observed in muscle fibers?

    <p>Sarcomere</p> Signup and view all the answers

    What do muscle cells contain that are the muscle equivalents of actin-containing microfilaments and myosin motor proteins?

    <p>Myofilaments</p> Signup and view all the answers

    What is primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filaments</p> Signup and view all the answers

    What is the 'business end' of myosin, linking to actin during contraction?

    <p>Globular heads</p> Signup and view all the answers

    What is the muscle cell cytoplasm that contains large amounts of glycosomes and myoglobin?

    <p>Sarcolemma</p> Signup and view all the answers

    What is the fusion product of hundreds of embryonic cells?

    <p>Skeletal muscle fiber</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Myofibrils</p> Signup and view all the answers

    What acts as motors to generate force during muscle contraction?

    <p>Myosin</p> Signup and view all the answers

    What is the large, cylindrical cells with multiple nuclei and sarcolemma?

    <p>Skeletal muscle fibers</p> Signup and view all the answers

    What contains myofibrils, sarcoplasmic reticulum, and T tubules?

    <p>Skeletal muscle fibers</p> Signup and view all the answers

    What splits ATP and uses the released energy to drive movement?

    <p>Myosin</p> Signup and view all the answers

    What involves thick and thin filaments forming cross bridges and swiveling around their point of attachment?

    <p>Sarcomere</p> Signup and view all the answers

    What is the approximate percentage of body mass made up by muscle tissue?

    <p>40%</p> Signup and view all the answers

    Where does cardiac muscle tissue occur?

    <p>Only in the heart</p> Signup and view all the answers

    What is the primary energy source used by muscles to exert force?

    <p>ATP</p> Signup and view all the answers

    What is the Latin origin of the word 'muscle'?

    <p>Musculus</p> Signup and view all the answers

    What is the connective tissue sheath that surrounds each individual muscle fiber?

    <p>Endomysium</p> Signup and view all the answers

    What is the dense irregular connective tissue that surrounds the whole muscle called?

    <p>Epimysium</p> Signup and view all the answers

    What is the functional unit of a myofibril responsible for the banding pattern observed in muscle fibers?

    <p>Sarcomere</p> Signup and view all the answers

    Which protein stabilizes the sarcolemma and links cytoskeleton to the extracellular matrix?

    <p>Dystrophin</p> Signup and view all the answers

    What is the most common type of muscle attachment?

    <p>Tendon attachment</p> Signup and view all the answers

    What is the aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>Manage symptoms</p> Signup and view all the answers

    What is the average length of a sarcomere?

    <p>10 micrometers</p> Signup and view all the answers

    What is primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filament</p> Signup and view all the answers

    Where does cardiac muscle tissue occur?

    <p>Hollow visceral organs</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Sliding filament mechanism</p> Signup and view all the answers

    What is the function of smooth muscle?

    <p>Regulating fluid flow</p> Signup and view all the answers

    What is the connective tissue that surrounds the entire muscle?

    <p>Epimysium</p> Signup and view all the answers

    What is the functional unit of a myofibril responsible for the banding pattern observed in muscle fibers?

    <p>Sarcomere</p> Signup and view all the answers

    What is the muscle cell cytoplasm that contains large amounts of glycosomes and myoglobin?

    <p>Sarcoplasmic reticulum</p> Signup and view all the answers

    What primarily composes the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filaments</p> Signup and view all the answers

    What is the 'business end' of myosin, linking to actin during contraction?

    <p>Myosin globular heads</p> Signup and view all the answers

    What is the large, cylindrical cells with multiple nuclei and sarcolemma?

    <p>Skeletal muscle fibers</p> Signup and view all the answers

    What is the aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>To slow disease progression and manage symptoms</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Tendons</p> Signup and view all the answers

    What is the Latin origin of the word 'muscle'?

    <p>Musculus</p> Signup and view all the answers

    What are the common symptoms of Duchenne muscular dystrophy (DMD) in affected boys?

    <p>Muscle weakness and wasting</p> Signup and view all the answers

    What is the inheritance pattern of muscular dystrophy?

    <p>X-linked recessive</p> Signup and view all the answers

    What is the connective tissue that surrounds each fascicle?

    <p>Perimysium</p> Signup and view all the answers

    What is the approximate occurrence of Duchenne muscular dystrophy (DMD) in male births?

    <p>1 in 10,000</p> Signup and view all the answers

    What is the function of dystrophin in muscle cells?

    <p>Stabilizes the sarcolemma and links cytoskeleton to the extracellular matrix</p> Signup and view all the answers

    Which protein controls myosin-actin interactions during muscle contraction?

    <p>Troponin and tropomyosin</p> Signup and view all the answers

    What is the primary aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>Prevent deformities and maintain mobility</p> Signup and view all the answers

    What is the role of titin in muscle cells?

    <p>Maintains the organization of the muscle cell and helps resist excessive stretching</p> Signup and view all the answers

    What are the common symptoms of Duchenne muscular dystrophy (DMD) in affected boys?

    <p>Muscle weakness, clumsiness, and falls</p> Signup and view all the answers

    What structures regulate muscle contraction in skeletal muscle fibers?

    <p>Sarcoplasmic reticulum and T tubules</p> Signup and view all the answers

    What causes tears in the fragile sarcolemma during muscle contraction in Duchenne muscular dystrophy (DMD)?

    <p>Dystrophin deficiency</p> Signup and view all the answers

    What is the approximate occurrence of Duchenne muscular dystrophy (DMD) in male births?

    <p>1 in 3600 births</p> Signup and view all the answers

    What is the function of myosin heads during muscle contraction?

    <p>Attach to the myosin-binding sites on actin</p> Signup and view all the answers

    What is the inheritance pattern of muscular dystrophy?

    <p>X-linked recessive</p> Signup and view all the answers

    Where is smooth muscle found?

    <p>In the walls of hollow organs</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Connective tissue</p> Signup and view all the answers

    What is the connective tissue that surrounds each individual muscle fiber?

    <p>Endomysium</p> Signup and view all the answers

    What is the functional unit of a muscle, composed of myofilaments made up of contractile proteins?

    <p>Sarcomere</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Tendons</p> Signup and view all the answers

    What is the contractile unit of a muscle, averaging 2 $ extmu$m in length?

    <p>Sarcomere</p> Signup and view all the answers

    What is the dense irregular connective tissue that surrounds the whole muscle called?

    <p>Epimysium</p> Signup and view all the answers

    What is the role of myosin heads during muscle contraction?

    <p>Forming cross-bridges with actin</p> Signup and view all the answers

    What is primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filament</p> Signup and view all the answers

    What is the Latin origin of the word 'muscle'?

    <p>Musculus</p> Signup and view all the answers

    What are myofibrils?

    <p>Rodlike contractile elements within the muscle cell</p> Signup and view all the answers

    Where do most skeletal muscles attach to bones?

    <p>Indirectly via tendons</p> Signup and view all the answers

    What is the fusion product of hundreds of embryonic cells?

    <p>Muscle fiber</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Sarcomere</p> Signup and view all the answers

    What is the study of cells and tissues called?

    <p>Histology</p> Signup and view all the answers

    Which branch of anatomy involves the study of body structures system by system?

    <p>Gross Anatomy</p> Signup and view all the answers

    What is the study of cells called?

    <p>Cytology</p> Signup and view all the answers

    Which type of anatomy studies the relationship between internal structures and the overlying skin surface?

    <p>Surface Anatomy</p> Signup and view all the answers

    What is the study of diseases related to?

    <p>Pathophysiology</p> Signup and view all the answers

    Which body system is responsible for the transportation of nutrients, gases, and wastes?

    <p>Cardiovascular system</p> Signup and view all the answers

    What is the primary energy source used by muscles to exert force?

    <p>ATP</p> Signup and view all the answers

    What is the primary aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>To improve muscle strength</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Connective tissue</p> Signup and view all the answers

    What is the maintenance of a constant internal environment despite changes in the external environment known as?

    <p>Homeostasis</p> Signup and view all the answers

    Which characteristic distinguishes muscles from other tissues?

    <p>Responsiveness</p> Signup and view all the answers

    What are the survival needs essential for maintaining life?

    <p>Nutrients, oxygen, water</p> Signup and view all the answers

    What is the primary focus of developmental anatomy?

    <p>Structural changes from fertilization to maturity</p> Signup and view all the answers

    What does physiology emphasize in the context of structure and function?

    <p>Complementarity of structure and function</p> Signup and view all the answers

    What is the role of feedback mechanisms in maintaining physiological limits?

    <p>To maintain physiological limits</p> Signup and view all the answers

    Which organ system is responsible for the production of offspring?

    <p>Reproductive system</p> Signup and view all the answers

    Which body cavity contains the stomach, intestines, and other organs?

    <p>Abdominopelvic cavity</p> Signup and view all the answers

    Which type of feedback loop is more prevalent in the body?

    <p>Negative feedback</p> Signup and view all the answers

    Which type of muscle is not striated and is not subject to voluntary control?

    <p>Smooth muscle</p> Signup and view all the answers

    What type of anatomical terminology allows accurate description of body parts and positions?

    <p>Regional terms</p> Signup and view all the answers

    What type of body cavity has two subdivisions, the cranial cavity and the vertebral cavity?

    <p>Dorsal body cavity</p> Signup and view all the answers

    Which body cavity contains the heart and lungs?

    <p>Thoracic cavity</p> Signup and view all the answers

    What type of body cavity is larger and anterior, and includes the thoracic and abdominopelvic cavities?

    <p>Ventral body cavity</p> Signup and view all the answers

    What are the body planes used for anatomical studies and imaging?

    <p>Transverse and sagittal planes</p> Signup and view all the answers

    Which body cavity is lined by a serous membrane and is not physically separated into abdominal and pelvic cavities?

    <p>Abdominopelvic cavity</p> Signup and view all the answers

    What division of the body is designated by regional terms?

    <p>Axial division</p> Signup and view all the answers

    What type of feedback system can be maintained through feedforward and feedback systems?

    <p>Negative feedback system</p> Signup and view all the answers

    What is the primary function of anatomical terminology such as directional terms and regional terms?

    <p>To describe body positions</p> Signup and view all the answers

    Which branch of anatomy involves the study of body structures system by system?

    <p>Gross anatomy</p> Signup and view all the answers

    What is the primary focus of developmental anatomy?

    <p>Studying the structural changes that occur in the body throughout the lifespan</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Myofibrils</p> Signup and view all the answers

    What is the aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>To slow down the progression of muscle degeneration and improve quality of life</p> Signup and view all the answers

    Which type of feedback loop is more prevalent in the body?

    <p>Negative feedback loop</p> Signup and view all the answers

    What type of cavity contains the stomach, intestines, and other organs?

    <p>Abdominopelvic cavity</p> Signup and view all the answers

    What is the function of anatomical terminology such as directional terms and regional terms?

    <p>To describe body parts and positions accurately</p> Signup and view all the answers

    What divides the body into axial and appendicular parts?

    <p>Body planes</p> Signup and view all the answers

    What are the subdivisions of the dorsal body cavity?

    <p>Cranial cavity and vertebral cavity</p> Signup and view all the answers

    What covers the walls of the ventral body cavity and the outer surfaces of the organs it contains?

    <p>Serous membrane</p> Signup and view all the answers

    What is the main function of the ventral body cavity?

    <p>Housing internal organs</p> Signup and view all the answers

    What is the role of body planes in anatomical studies and imaging?

    <p>To provide reference points for describing the body</p> Signup and view all the answers

    What is the primary purpose of feedforward and feedback systems in maintaining homeostasis?

    <p>To maintain stability in the body's internal environment</p> Signup and view all the answers

    What are the two subdivisions of the dorsal body cavity?

    <p>Cranial cavity and vertebral cavity</p> Signup and view all the answers

    What are the main organs contained in the thoracic cavity?

    <p>Lungs, heart, and other thoracic organs</p> Signup and view all the answers

    What is the main function of negative feedback loops?

    <p>To maintain stability in the body's internal environment</p> Signup and view all the answers

    Which of the following is a subdivision of physiology?

    <p>Pathophysiology</p> Signup and view all the answers

    What is the primary emphasis of physiology?

    <p>Homeostasis</p> Signup and view all the answers

    Which characteristic is NOT included in the major body organ systems?

    <p>Metabolic</p> Signup and view all the answers

    What is a key component of survival needs for the body?

    <p>Normal body temperature</p> Signup and view all the answers

    What is the primary aim of homeostasis?

    <p>To rely on feedback mechanisms</p> Signup and view all the answers

    What is the approximate range for blood glucose level to be maintained?

    <p>70-110mg/100ml</p> Signup and view all the answers

    Which of the following is NOT a basic life process?

    <p>Photosynthesis</p> Signup and view all the answers

    What is the study of mechanical, physical, and biochemical functions at organ and cellular levels?

    <p>Physiology</p> Signup and view all the answers

    What is the primary emphasis of developmental anatomy?

    <p>Structural changes from fertilization to maturity</p> Signup and view all the answers

    Which of the following is a subdivision of physiology?

    <p>Neurophysiology</p> Signup and view all the answers

    What is NOT a characteristic of the body's characteristics?

    <p>Aging</p> Signup and view all the answers

    What is the primary study of diseases?

    <p>Pathology</p> Signup and view all the answers

    Study Notes

    Microscopic Anatomy of Skeletal Muscle Fiber

    • Skeletal muscle fibers are large, cylindrical cells with multiple nuclei and sarcolemma.
    • Each fiber is produced by the fusion of hundreds of embryonic cells.
    • Sarcolemma, the muscle cell cytoplasm, contains large amounts of glycosomes and myoglobin.
    • Muscle cells contain myofibrils, sarcoplasmic reticulum, and T tubules.
    • Myofibrils consist of myofilaments, which are the muscle equivalents of actin-containing microfilaments and myosin motor proteins.
    • Muscle contraction depends on myosin- and actin-containing myofilaments.
    • Thick filaments are primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains.
    • The globular heads of myosin are the "business end" of myosin, linking to actin during contraction.
    • Myosin splits ATP and uses the released energy to drive movement, with each thick filament containing about 300 myosin molecules.
    • Muscle contraction involves thick and thin filaments forming cross bridges and swiveling around their point of attachment.
    • Myosin acts as motors to generate force during muscle contraction.
    • The sarcomere, the functional unit of a myofibril, extends from one Z disc to the next and is responsible for the banding pattern observed in muscle fibers.

    Skeletal Muscle Structure and Function Overview

    • Each fascicle is surrounded by a layer of dense irregular connective tissue called perimysium
    • In direct attachments, the epimysium of the muscle is fused to the periosteum of a bone or perichondrium of a cartilage
    • Indirect attachments of muscles are more common due to their durability and small size
    • Tendons, mostly tough collagen fibers, anchor muscles to skeletal elements or other muscles
    • A muscle consists of hundreds to thousands of muscle cells, connective tissue wrappings, blood vessels, and nerve fibers
    • A fascicle is a discrete bundle of muscle cells, segregated from the rest of the muscle by a connective tissue sheath
    • A muscle fiber is an elongated multinucleate cell with a banded appearance
    • Myofibrils are rodlike contractile elements that occupy most of the muscle cell volume
    • A sarcomere is the contractile unit of a muscle, composed of myofilaments made up of contractile proteins
    • Contractile myofilaments are of two types: thick (myosin) and thin (actin) filaments
    • The sliding of thin filaments past thick filaments produces muscle shortening
    • A sarcomere is the smallest contractile unit of a muscle, averaging 2 µm in length

    Homeostasis and Anatomical Terms: Key Concepts in Human Biology

    • Homeostasis is disrupted by external stimuli like intense heat, cold, and lack of oxygen, as well as internal stimuli like psychological stresses and exercise.
    • Homeostasis involves receptors, a control center, and effectors, and can be maintained through feedforward and feedback systems.
    • Feedback systems include negative and positive feedback loops, with negative feedback being more prevalent in the body.
    • Anatomical terminology, such as directional terms and regional terms, allows accurate description of body parts and positions.
    • The body is divided into axial and appendicular parts, with regional terms used to designate specific areas within these divisions.
    • Body planes, including sagittal, frontal, and transverse planes, are used for anatomical studies and imaging.
    • The dorsal body cavity has two subdivisions, the cranial cavity and the vertebral cavity, protecting the nervous system organs.
    • The ventral body cavity, larger and anterior, includes the thoracic cavity and the abdominopelvic cavity, housing internal organs.
    • The thoracic cavity contains the lungs, heart, and other thoracic organs, while the abdominopelvic cavity contains the stomach, intestines, and other organs.
    • The abdominopelvic cavity is not physically separated into abdominal and pelvic cavities and is lined by a serous membrane.
    • The bowl-shaped pelvis tips away from the perpendicular, causing the abdominal and pelvic cavities to be misaligned.
    • The serous membrane covers the walls of the ventral body cavity and the outer surfaces of the organs it contains, including the heart.

    Anatomy and Physiology Overview

    • Developmental anatomy studies structural changes from fertilization to maturity
    • Physiology focuses on mechanical, physical, and biochemical functions at organ and cellular levels
    • Subdivisions of physiology include pathophysiology, exercise physiology, and neurophysiology
    • Physiology emphasizes the principle of complementarity of structure and function and homeostasis
    • Physiology is also the study of diseases
    • Major body organ systems include integumentary, skeletal, muscular, nervous, endocrine, cardiovascular, lymphatic, respiratory, urinary, digestive, and reproductive
    • The body's characteristics include metabolism, responsiveness, movement, growth, differentiation, digestion, and reproduction
    • Basic life processes include metabolism, digestion, excretion, responsiveness, movement, growth, differentiation, and reproduction
    • Survival needs include nutrients, oxygen, water, normal body temperature, and appropriate atmospheric pressure
    • Homeostasis is the maintenance of a constant internal environment despite changes in the external environment
    • Homeostasis relies on feedback mechanisms to maintain physiological limits
    • For example, blood glucose level is kept within a narrow range of 70-110mg/100ml

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    Description

    Test your knowledge of the microscopic anatomy of skeletal muscle fibers with this quiz. Explore the structure and components of muscle cells, including myofibrils, myofilaments, sarcomeres, and the role of myosin and actin in muscle contraction.

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