Microscopic Anatomy of Skeletal Muscle Fiber Quiz
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Questions and Answers

What is the dominant tissue in the heart and in the walls of other hollow organs?

  • Nervous tissue
  • Muscle tissue (correct)
  • Connective tissue
  • Epithelial tissue
  • What distinguishes muscles from other tissues?

  • Ability to produce hormones
  • Ability to conduct electrical impulses
  • Ability to convert chemical energy into mechanical energy (correct)
  • Ability to store and release energy
  • Where does cardiac muscle tissue occur?

  • In both smooth and skeletal muscles
  • Only in the walls of other hollow organs
  • Only in the heart (correct)
  • In both the heart and skeletal muscles
  • What is the Latin origin of the word 'muscle'?

    <p>Nius meaning 'little mouse'</p> Signup and view all the answers

    What type of muscle is not striated and is also not subject to voluntary control?

    <p>Smooth muscle</p> Signup and view all the answers

    Where is smooth muscle found?

    <p>In hollow visceral organs</p> Signup and view all the answers

    What type of muscle cells are striated and involuntary?

    <p>Cardiac muscle</p> Signup and view all the answers

    Which muscle type contracts at a steady rate but can speed up with neural controls?

    <p>Cardiac muscle</p> Signup and view all the answers

    What is the function of smooth muscle?

    <p>Regulating fluid flow</p> Signup and view all the answers

    What surrounds each individual muscle fiber?

    <p>Endomysium</p> Signup and view all the answers

    What is the dense irregular connective tissue that surrounds the whole muscle called?

    <p>Epimysium</p> Signup and view all the answers

    What controls the activity of skeletal muscle fibers?

    <p>Nerve endings</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Connective tissue sheaths</p> Signup and view all the answers

    What transmits the pulling force from muscle fibers to the bone to be moved?

    <p>Connective tissue sheaths</p> Signup and view all the answers

    Where do most skeletal muscles attach to bones?

    <p>At least two places</p> Signup and view all the answers

    What is the connective tissue that surrounds each fascicle?

    <p>Perimysium</p> Signup and view all the answers

    What are tendons mostly composed of?

    <p>Collagen fibers</p> Signup and view all the answers

    What is a muscle fiber?

    <p>A single muscle cell</p> Signup and view all the answers

    What are myofibrils?

    <p>Rodlike contractile elements</p> Signup and view all the answers

    What is a sarcomere?

    <p>The contractile unit of a muscle</p> Signup and view all the answers

    What produces muscle shortening?

    <p>Sliding of thin filaments past thick filaments</p> Signup and view all the answers

    What is the average length of a sarcomere?

    <p>2 µm</p> Signup and view all the answers

    What type of filaments are myosin filaments?

    <p>Contractile</p> Signup and view all the answers

    What type of filaments are actin filaments?

    <p>Non-contractile</p> Signup and view all the answers

    What is the most common type of muscle attachment?

    <p>Indirect attachment</p> Signup and view all the answers

    What is the connective tissue that surrounds the entire muscle?

    <p>Epimysium</p> Signup and view all the answers

    What is the function of a fascicle?

    <p>To segregate muscle cells from the rest of the muscle</p> Signup and view all the answers

    What is the inheritance pattern of muscular dystrophy?

    <p>X-linked recessive</p> Signup and view all the answers

    What is the approximate occurrence of Duchenne muscular dystrophy (DMD) in male births?

    <p>1 in 3600 births</p> Signup and view all the answers

    What are the common symptoms of Duchenne muscular dystrophy (DMD) in affected boys?

    <p>Muscle weakness, clumsiness, and falls</p> Signup and view all the answers

    Which protein stabilizes the sarcolemma and links cytoskeleton to the extracellular matrix?

    <p>Dystrophin</p> Signup and view all the answers

    What is the function of titin in muscle cells?

    <p>Maintaining muscle cell organization and resisting excessive stretching</p> Signup and view all the answers

    What structures regulate muscle contraction in skeletal muscle fibers?

    <p>Sarcoplasmic reticulum and T tubules</p> Signup and view all the answers

    What is the role of myosin heads during muscle contraction?

    <p>Binding to the myosin-binding sites on actin</p> Signup and view all the answers

    Which components control myosin-actin interactions during muscle contraction?

    <p>Troponin and tropomyosin</p> Signup and view all the answers

    What happens to the fragile sarcolemma during muscle contraction in DMD?

    <p>It tears, leading to muscle damage</p> Signup and view all the answers

    What is the aim of current treatments for DMD?

    <p>Preventing deformities and maintaining mobility</p> Signup and view all the answers

    In DMD, the progression of muscle weakness occurs from extremities to which parts of the body?

    <p>Head and neck</p> Signup and view all the answers

    With supportive care, how long can DMD patients typically live?

    <p>Into their 30s and beyond</p> Signup and view all the answers

    What is the functional unit of a myofibril responsible for the banding pattern observed in muscle fibers?

    <p>Sarcomere</p> Signup and view all the answers

    What do muscle cells contain that are the muscle equivalents of actin-containing microfilaments and myosin motor proteins?

    <p>Myofilaments</p> Signup and view all the answers

    What is primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filaments</p> Signup and view all the answers

    What is the 'business end' of myosin, linking to actin during contraction?

    <p>Globular heads</p> Signup and view all the answers

    What is the muscle cell cytoplasm that contains large amounts of glycosomes and myoglobin?

    <p>Sarcolemma</p> Signup and view all the answers

    What is the fusion product of hundreds of embryonic cells?

    <p>Skeletal muscle fiber</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Myofibrils</p> Signup and view all the answers

    What acts as motors to generate force during muscle contraction?

    <p>Myosin</p> Signup and view all the answers

    What is the large, cylindrical cells with multiple nuclei and sarcolemma?

    <p>Skeletal muscle fibers</p> Signup and view all the answers

    What contains myofibrils, sarcoplasmic reticulum, and T tubules?

    <p>Skeletal muscle fibers</p> Signup and view all the answers

    What splits ATP and uses the released energy to drive movement?

    <p>Myosin</p> Signup and view all the answers

    What involves thick and thin filaments forming cross bridges and swiveling around their point of attachment?

    <p>Sarcomere</p> Signup and view all the answers

    What is the approximate percentage of body mass made up by muscle tissue?

    <p>40%</p> Signup and view all the answers

    Where does cardiac muscle tissue occur?

    <p>Only in the heart</p> Signup and view all the answers

    What is the primary energy source used by muscles to exert force?

    <p>ATP</p> Signup and view all the answers

    What is the Latin origin of the word 'muscle'?

    <p>Musculus</p> Signup and view all the answers

    What is the connective tissue sheath that surrounds each individual muscle fiber?

    <p>Endomysium</p> Signup and view all the answers

    What is the dense irregular connective tissue that surrounds the whole muscle called?

    <p>Epimysium</p> Signup and view all the answers

    What is the functional unit of a myofibril responsible for the banding pattern observed in muscle fibers?

    <p>Sarcomere</p> Signup and view all the answers

    Which protein stabilizes the sarcolemma and links cytoskeleton to the extracellular matrix?

    <p>Dystrophin</p> Signup and view all the answers

    What is the most common type of muscle attachment?

    <p>Tendon attachment</p> Signup and view all the answers

    What is the aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>Manage symptoms</p> Signup and view all the answers

    What is the average length of a sarcomere?

    <p>10 micrometers</p> Signup and view all the answers

    What is primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filament</p> Signup and view all the answers

    Where does cardiac muscle tissue occur?

    <p>Hollow visceral organs</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Sliding filament mechanism</p> Signup and view all the answers

    What is the function of smooth muscle?

    <p>Regulating fluid flow</p> Signup and view all the answers

    What is the connective tissue that surrounds the entire muscle?

    <p>Epimysium</p> Signup and view all the answers

    What is the functional unit of a myofibril responsible for the banding pattern observed in muscle fibers?

    <p>Sarcomere</p> Signup and view all the answers

    What is the muscle cell cytoplasm that contains large amounts of glycosomes and myoglobin?

    <p>Sarcoplasmic reticulum</p> Signup and view all the answers

    What primarily composes the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filaments</p> Signup and view all the answers

    What is the 'business end' of myosin, linking to actin during contraction?

    <p>Myosin globular heads</p> Signup and view all the answers

    What is the large, cylindrical cells with multiple nuclei and sarcolemma?

    <p>Skeletal muscle fibers</p> Signup and view all the answers

    What is the aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>To slow disease progression and manage symptoms</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Tendons</p> Signup and view all the answers

    What is the Latin origin of the word 'muscle'?

    <p>Musculus</p> Signup and view all the answers

    What are the common symptoms of Duchenne muscular dystrophy (DMD) in affected boys?

    <p>Muscle weakness and wasting</p> Signup and view all the answers

    What is the inheritance pattern of muscular dystrophy?

    <p>X-linked recessive</p> Signup and view all the answers

    What is the connective tissue that surrounds each fascicle?

    <p>Perimysium</p> Signup and view all the answers

    What is the approximate occurrence of Duchenne muscular dystrophy (DMD) in male births?

    <p>1 in 10,000</p> Signup and view all the answers

    What is the function of dystrophin in muscle cells?

    <p>Stabilizes the sarcolemma and links cytoskeleton to the extracellular matrix</p> Signup and view all the answers

    Which protein controls myosin-actin interactions during muscle contraction?

    <p>Troponin and tropomyosin</p> Signup and view all the answers

    What is the primary aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>Prevent deformities and maintain mobility</p> Signup and view all the answers

    What is the role of titin in muscle cells?

    <p>Maintains the organization of the muscle cell and helps resist excessive stretching</p> Signup and view all the answers

    What are the common symptoms of Duchenne muscular dystrophy (DMD) in affected boys?

    <p>Muscle weakness, clumsiness, and falls</p> Signup and view all the answers

    What structures regulate muscle contraction in skeletal muscle fibers?

    <p>Sarcoplasmic reticulum and T tubules</p> Signup and view all the answers

    What causes tears in the fragile sarcolemma during muscle contraction in Duchenne muscular dystrophy (DMD)?

    <p>Dystrophin deficiency</p> Signup and view all the answers

    What is the approximate occurrence of Duchenne muscular dystrophy (DMD) in male births?

    <p>1 in 3600 births</p> Signup and view all the answers

    What is the function of myosin heads during muscle contraction?

    <p>Attach to the myosin-binding sites on actin</p> Signup and view all the answers

    What is the inheritance pattern of muscular dystrophy?

    <p>X-linked recessive</p> Signup and view all the answers

    Where is smooth muscle found?

    <p>In the walls of hollow organs</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Connective tissue</p> Signup and view all the answers

    What is the connective tissue that surrounds each individual muscle fiber?

    <p>Endomysium</p> Signup and view all the answers

    What is the functional unit of a muscle, composed of myofilaments made up of contractile proteins?

    <p>Sarcomere</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Tendons</p> Signup and view all the answers

    What is the contractile unit of a muscle, averaging 2 $ extmu$m in length?

    <p>Sarcomere</p> Signup and view all the answers

    What is the dense irregular connective tissue that surrounds the whole muscle called?

    <p>Epimysium</p> Signup and view all the answers

    What is the role of myosin heads during muscle contraction?

    <p>Forming cross-bridges with actin</p> Signup and view all the answers

    What is primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains?

    <p>Thick filament</p> Signup and view all the answers

    What is the Latin origin of the word 'muscle'?

    <p>Musculus</p> Signup and view all the answers

    What are myofibrils?

    <p>Rodlike contractile elements within the muscle cell</p> Signup and view all the answers

    Where do most skeletal muscles attach to bones?

    <p>Indirectly via tendons</p> Signup and view all the answers

    What is the fusion product of hundreds of embryonic cells?

    <p>Muscle fiber</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Sarcomere</p> Signup and view all the answers

    What is the study of cells and tissues called?

    <p>Histology</p> Signup and view all the answers

    Which branch of anatomy involves the study of body structures system by system?

    <p>Gross Anatomy</p> Signup and view all the answers

    What is the study of cells called?

    <p>Cytology</p> Signup and view all the answers

    Which type of anatomy studies the relationship between internal structures and the overlying skin surface?

    <p>Surface Anatomy</p> Signup and view all the answers

    What is the study of diseases related to?

    <p>Pathophysiology</p> Signup and view all the answers

    Which body system is responsible for the transportation of nutrients, gases, and wastes?

    <p>Cardiovascular system</p> Signup and view all the answers

    What is the primary energy source used by muscles to exert force?

    <p>ATP</p> Signup and view all the answers

    What is the primary aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>To improve muscle strength</p> Signup and view all the answers

    What reinforces the muscle and supports its function?

    <p>Connective tissue</p> Signup and view all the answers

    What is the maintenance of a constant internal environment despite changes in the external environment known as?

    <p>Homeostasis</p> Signup and view all the answers

    Which characteristic distinguishes muscles from other tissues?

    <p>Responsiveness</p> Signup and view all the answers

    What are the survival needs essential for maintaining life?

    <p>Nutrients, oxygen, water</p> Signup and view all the answers

    What is the primary focus of developmental anatomy?

    <p>Structural changes from fertilization to maturity</p> Signup and view all the answers

    What does physiology emphasize in the context of structure and function?

    <p>Complementarity of structure and function</p> Signup and view all the answers

    What is the role of feedback mechanisms in maintaining physiological limits?

    <p>To maintain physiological limits</p> Signup and view all the answers

    Which organ system is responsible for the production of offspring?

    <p>Reproductive system</p> Signup and view all the answers

    Which body cavity contains the stomach, intestines, and other organs?

    <p>Abdominopelvic cavity</p> Signup and view all the answers

    Which type of feedback loop is more prevalent in the body?

    <p>Negative feedback</p> Signup and view all the answers

    Which type of muscle is not striated and is not subject to voluntary control?

    <p>Smooth muscle</p> Signup and view all the answers

    What type of anatomical terminology allows accurate description of body parts and positions?

    <p>Regional terms</p> Signup and view all the answers

    What type of body cavity has two subdivisions, the cranial cavity and the vertebral cavity?

    <p>Dorsal body cavity</p> Signup and view all the answers

    Which body cavity contains the heart and lungs?

    <p>Thoracic cavity</p> Signup and view all the answers

    What type of body cavity is larger and anterior, and includes the thoracic and abdominopelvic cavities?

    <p>Ventral body cavity</p> Signup and view all the answers

    What are the body planes used for anatomical studies and imaging?

    <p>Transverse and sagittal planes</p> Signup and view all the answers

    Which body cavity is lined by a serous membrane and is not physically separated into abdominal and pelvic cavities?

    <p>Abdominopelvic cavity</p> Signup and view all the answers

    What division of the body is designated by regional terms?

    <p>Axial division</p> Signup and view all the answers

    What type of feedback system can be maintained through feedforward and feedback systems?

    <p>Negative feedback system</p> Signup and view all the answers

    What is the primary function of anatomical terminology such as directional terms and regional terms?

    <p>To describe body positions</p> Signup and view all the answers

    Which branch of anatomy involves the study of body structures system by system?

    <p>Gross anatomy</p> Signup and view all the answers

    What is the primary focus of developmental anatomy?

    <p>Studying the structural changes that occur in the body throughout the lifespan</p> Signup and view all the answers

    What is responsible for muscle contraction and depends on myosin- and actin-containing myofilaments?

    <p>Myofibrils</p> Signup and view all the answers

    What is the aim of current treatments for Duchenne muscular dystrophy (DMD)?

    <p>To slow down the progression of muscle degeneration and improve quality of life</p> Signup and view all the answers

    Which type of feedback loop is more prevalent in the body?

    <p>Negative feedback loop</p> Signup and view all the answers

    What type of cavity contains the stomach, intestines, and other organs?

    <p>Abdominopelvic cavity</p> Signup and view all the answers

    What is the function of anatomical terminology such as directional terms and regional terms?

    <p>To describe body parts and positions accurately</p> Signup and view all the answers

    What divides the body into axial and appendicular parts?

    <p>Body planes</p> Signup and view all the answers

    What are the subdivisions of the dorsal body cavity?

    <p>Cranial cavity and vertebral cavity</p> Signup and view all the answers

    What covers the walls of the ventral body cavity and the outer surfaces of the organs it contains?

    <p>Serous membrane</p> Signup and view all the answers

    What is the main function of the ventral body cavity?

    <p>Housing internal organs</p> Signup and view all the answers

    What is the role of body planes in anatomical studies and imaging?

    <p>To provide reference points for describing the body</p> Signup and view all the answers

    What is the primary purpose of feedforward and feedback systems in maintaining homeostasis?

    <p>To maintain stability in the body's internal environment</p> Signup and view all the answers

    What are the two subdivisions of the dorsal body cavity?

    <p>Cranial cavity and vertebral cavity</p> Signup and view all the answers

    What are the main organs contained in the thoracic cavity?

    <p>Lungs, heart, and other thoracic organs</p> Signup and view all the answers

    What is the main function of negative feedback loops?

    <p>To maintain stability in the body's internal environment</p> Signup and view all the answers

    Which of the following is a subdivision of physiology?

    <p>Pathophysiology</p> Signup and view all the answers

    What is the primary emphasis of physiology?

    <p>Homeostasis</p> Signup and view all the answers

    Which characteristic is NOT included in the major body organ systems?

    <p>Metabolic</p> Signup and view all the answers

    What is a key component of survival needs for the body?

    <p>Normal body temperature</p> Signup and view all the answers

    What is the primary aim of homeostasis?

    <p>To rely on feedback mechanisms</p> Signup and view all the answers

    What is the approximate range for blood glucose level to be maintained?

    <p>70-110mg/100ml</p> Signup and view all the answers

    Which of the following is NOT a basic life process?

    <p>Photosynthesis</p> Signup and view all the answers

    What is the study of mechanical, physical, and biochemical functions at organ and cellular levels?

    <p>Physiology</p> Signup and view all the answers

    What is the primary emphasis of developmental anatomy?

    <p>Structural changes from fertilization to maturity</p> Signup and view all the answers

    Which of the following is a subdivision of physiology?

    <p>Neurophysiology</p> Signup and view all the answers

    What is NOT a characteristic of the body's characteristics?

    <p>Aging</p> Signup and view all the answers

    What is the primary study of diseases?

    <p>Pathology</p> Signup and view all the answers

    Study Notes

    Microscopic Anatomy of Skeletal Muscle Fiber

    • Skeletal muscle fibers are large, cylindrical cells with multiple nuclei and sarcolemma.
    • Each fiber is produced by the fusion of hundreds of embryonic cells.
    • Sarcolemma, the muscle cell cytoplasm, contains large amounts of glycosomes and myoglobin.
    • Muscle cells contain myofibrils, sarcoplasmic reticulum, and T tubules.
    • Myofibrils consist of myofilaments, which are the muscle equivalents of actin-containing microfilaments and myosin motor proteins.
    • Muscle contraction depends on myosin- and actin-containing myofilaments.
    • Thick filaments are primarily composed of the protein myosin, with each myosin molecule consisting of six polypeptide chains.
    • The globular heads of myosin are the "business end" of myosin, linking to actin during contraction.
    • Myosin splits ATP and uses the released energy to drive movement, with each thick filament containing about 300 myosin molecules.
    • Muscle contraction involves thick and thin filaments forming cross bridges and swiveling around their point of attachment.
    • Myosin acts as motors to generate force during muscle contraction.
    • The sarcomere, the functional unit of a myofibril, extends from one Z disc to the next and is responsible for the banding pattern observed in muscle fibers.

    Skeletal Muscle Structure and Function Overview

    • Each fascicle is surrounded by a layer of dense irregular connective tissue called perimysium
    • In direct attachments, the epimysium of the muscle is fused to the periosteum of a bone or perichondrium of a cartilage
    • Indirect attachments of muscles are more common due to their durability and small size
    • Tendons, mostly tough collagen fibers, anchor muscles to skeletal elements or other muscles
    • A muscle consists of hundreds to thousands of muscle cells, connective tissue wrappings, blood vessels, and nerve fibers
    • A fascicle is a discrete bundle of muscle cells, segregated from the rest of the muscle by a connective tissue sheath
    • A muscle fiber is an elongated multinucleate cell with a banded appearance
    • Myofibrils are rodlike contractile elements that occupy most of the muscle cell volume
    • A sarcomere is the contractile unit of a muscle, composed of myofilaments made up of contractile proteins
    • Contractile myofilaments are of two types: thick (myosin) and thin (actin) filaments
    • The sliding of thin filaments past thick filaments produces muscle shortening
    • A sarcomere is the smallest contractile unit of a muscle, averaging 2 µm in length

    Homeostasis and Anatomical Terms: Key Concepts in Human Biology

    • Homeostasis is disrupted by external stimuli like intense heat, cold, and lack of oxygen, as well as internal stimuli like psychological stresses and exercise.
    • Homeostasis involves receptors, a control center, and effectors, and can be maintained through feedforward and feedback systems.
    • Feedback systems include negative and positive feedback loops, with negative feedback being more prevalent in the body.
    • Anatomical terminology, such as directional terms and regional terms, allows accurate description of body parts and positions.
    • The body is divided into axial and appendicular parts, with regional terms used to designate specific areas within these divisions.
    • Body planes, including sagittal, frontal, and transverse planes, are used for anatomical studies and imaging.
    • The dorsal body cavity has two subdivisions, the cranial cavity and the vertebral cavity, protecting the nervous system organs.
    • The ventral body cavity, larger and anterior, includes the thoracic cavity and the abdominopelvic cavity, housing internal organs.
    • The thoracic cavity contains the lungs, heart, and other thoracic organs, while the abdominopelvic cavity contains the stomach, intestines, and other organs.
    • The abdominopelvic cavity is not physically separated into abdominal and pelvic cavities and is lined by a serous membrane.
    • The bowl-shaped pelvis tips away from the perpendicular, causing the abdominal and pelvic cavities to be misaligned.
    • The serous membrane covers the walls of the ventral body cavity and the outer surfaces of the organs it contains, including the heart.

    Anatomy and Physiology Overview

    • Developmental anatomy studies structural changes from fertilization to maturity
    • Physiology focuses on mechanical, physical, and biochemical functions at organ and cellular levels
    • Subdivisions of physiology include pathophysiology, exercise physiology, and neurophysiology
    • Physiology emphasizes the principle of complementarity of structure and function and homeostasis
    • Physiology is also the study of diseases
    • Major body organ systems include integumentary, skeletal, muscular, nervous, endocrine, cardiovascular, lymphatic, respiratory, urinary, digestive, and reproductive
    • The body's characteristics include metabolism, responsiveness, movement, growth, differentiation, digestion, and reproduction
    • Basic life processes include metabolism, digestion, excretion, responsiveness, movement, growth, differentiation, and reproduction
    • Survival needs include nutrients, oxygen, water, normal body temperature, and appropriate atmospheric pressure
    • Homeostasis is the maintenance of a constant internal environment despite changes in the external environment
    • Homeostasis relies on feedback mechanisms to maintain physiological limits
    • For example, blood glucose level is kept within a narrow range of 70-110mg/100ml

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