19 Questions
What is the primary function of microcirculation?
Transport of nutrients to the tissues and the removal of cell excreta
What is the composition of the capillary walls?
Single-layer, highly permeable endothelial cells
What is the term for the intermittent contraction of metarterioles and precapillary sphincters?
Vasomotion
Why is the microcirculation of each organ organized differently?
To serve the specific needs of each organ
What is the primary objective of the Starling equation?
To predict fluid movement across the capillary wall
What is the main factor that regulates vasomotion in the tissues?
Concentration of oxygen
Which type of capillary has a high degree of permeability due to the presence of fenestrae?
Fenestrated capillaries
What percentage of the body's water is found intracellularly?
2/3
What is the main function of the lymphatic system?
To provide an accessory route for fluid to flow from the interstitial spaces into the blood
What is the effect of an increase in adenosine on local vascular smooth muscle?
Relaxation
What is the role of endothelin in the vascular system?
Constriction
What is the term for the ability of a tissue to maintain blood flow relatively constant over a wide range of arterial pressures?
Auto-regulation
What is the stimulus for the release of adenosine in the vascular system?
Insufficient blood flow
What is the role of the endothelium in the vascular system?
Synthesizing vasoactive substances
What is the effect of an increase in IP3 on vascular smooth muscle?
Increased Ca++
What is the mechanism of the myogenic theory of auto-regulation?
Dilation of arterioles in response to decreased wall tension
What is the term for the growth of new blood vessels?
Angiogenesis
What is the factor that regulates brain blood flow?
CO2 and H+
What is the type of hyperemia that is a metabolic control mechanism?
Reactive hyperemia
Test your understanding of microcirculation and lymphatics, including the structure and function of capillary walls, the Starling equation, and the effects of pressure and resistance on fluid movement. Learn how to predict changes in capillary pressure and their consequences.
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