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Microbiology: Virology Lecture 3 - Viral Replication Cycle

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17 Questions

Which of the following is true about viruses?

Viruses are obligate intracellular parasites.

What is the role of the host cell in viral replication?

Host cells provide the necessary machinery, energy sources, and enzymes for viral genome replication and translation of viral mRNAs.

What is the difference between a susceptible cell and a permissive cell?

A susceptible cell may or may not be able to support viral replication, while a permissive cell can support viral replication.

What is the first step in the viral replication cycle?

Attachment and entry

Which of the following is a characteristic of RNA viruses?

They rely on the host cell's machinery for translation of viral mRNAs.

What is the role of reverse transcriptase in the viral replication cycle?

It converts the viral RNA genome into a DNA provirus that integrates into the host cell's genome.

What is the difference between the replication cycles of DNA viruses and RNA viruses?

DNA viruses rely on host cell DNA-dependent DNA polymerase for genome replication, while RNA viruses rely on host cell RNA-dependent RNA polymerase.

Which of the following is a characteristic of DNA viruses?

They can directly integrate their genome into the host cell's chromosome.

What is the role of viral mRNA synthesis in the viral replication cycle?

It facilitates the translation of viral proteins required for genome replication and assembly.

Which of the following is a characteristic of the viral replication cycle?

Viruses rely on the host cell's machinery and resources for various steps of the replication cycle.

What is the primary function of reverse transcriptase in viral replication?

Synthesizing DNA from RNA

In viral replication, which type of viruses package the viral RNA-dependent RNA polymerase along with the genome?

dsRNA viruses

Which enzyme is responsible for synthesizing long chains of nucleic acids in most DNA viruses?

DNA-dependent DNA polymerase

What is the general mechanism of entry into host cells for non-enveloped viruses?

Disrupting the lysosomal membrane

Which step of the viral replication cycle involves acquisition of an envelope in some viruses?

Release

How do enveloped viruses primarily exit host cells during release?

B and C

Which classification of viral genomes includes RNA genomes that use reverse transcriptase during replication?

Type III

Learn about the viral replication cycle in this introduction to microbiology lecture. Understand how viruses are obligate intracellular parasites and require host cell functions for reproduction of new infectious particles.

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