Microbiology Unit 14: Gram-Negative Cocci and Rods
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Questions and Answers

Which agar is best suited for the growth of Neisseria meningitidis?

  • MacConkey agar
  • Mannitol salt agar
  • Chocolate agar (correct)
  • Blood agar
  • What is the natural habitat of Neisseria meningitidis?

  • Soil and water
  • Respiratory tract of animals
  • Human skin
  • Human pharynx (nasopharynx) (correct)
  • What is the transmission route of Neisseria meningitidis?

  • Transmission through contaminated food or water
  • Vector-borne transmission
  • Fecal-oral route
  • Transmission by droplets of oropharyngeal and respiratory secretions (correct)
  • What is the disease caused by hematogenous dissemination of Neisseria meningitidis called?

    <p>Meningococcemia</p> Signup and view all the answers

    Which species of Neisseria are rare opportunistic pathogens?

    <p>N. sicca, N. mucosa, N. lactamica</p> Signup and view all the answers

    What is the differentiation between meningococcus and gonococcus based on?

    <p>Biochemical identification</p> Signup and view all the answers

    Which antigenic structure of enterobacteria is associated with the surface and capsular polysaccharide?

    <p>K antigen</p> Signup and view all the answers

    What type of infections are most commonly produced by Enterobacteriaceae?

    <p>Urinary tract infections</p> Signup and view all the answers

    Which strain of Escherichia coli is responsible for traveler's diarrhea and infant diarrhea?

    <p>Enterotoxigenic (ETEC)</p> Signup and view all the answers

    What are the etiological agents of bacillary dysentery?

    <p>Shigella</p> Signup and view all the answers

    Which species of Salmonella is associated with typhoid fever?

    <p>S. typhi</p> Signup and view all the answers

    What is the main symptom of bubonic plague caused by Yersinia pestis?

    <p>Bubo formation</p> Signup and view all the answers

    How is typhoid fever typically transmitted?

    <p>Fecal-oral transmission</p> Signup and view all the answers

    Which antigenic structure of enterobacteria is associated with the flagella?

    <p>H antigen</p> Signup and view all the answers

    Which type of infections are uncommon in healthy people but can be caused by strict pathogenic strains of Escherichia coli?

    <p>Gastrointestinal symptoms</p> Signup and view all the answers

    What is the main route of transmission for gastroenteritis?

    <p>Fecal-oral transmission</p> Signup and view all the answers

    Which serogroups of Neisseria meningitidis are the main causes of disease in Spain?

    <p>B, C, Y, W135</p> Signup and view all the answers

    At what age does meningitis due to Neisseria meningitidis peak in Spain?

    <p>6-12 months</p> Signup and view all the answers

    In which months do most cases of meningitis due to Neisseria meningitidis occur in Spain?

    <p>December - March</p> Signup and view all the answers

    What is the first-line treatment for Neisseria meningitidis bacteremia?

    <p>Penicillin G</p> Signup and view all the answers

    Which type of vaccine is more efficient and provides a durable response against Neisseria meningitidis serogroup C?

    <p>Conjugate</p> Signup and view all the answers

    How is Neisseria gonorrhoeae classified based on its morphology?

    <p>Gram-negative cocci in pairs</p> Signup and view all the answers

    In which type of infections do uterine cervix, urethra, anal portion of the rectum, pharynx, and conjunctiva get affected by Neisseria gonorrhoeae?

    <p><strong>Sexually transmitted and perinatal disease</strong></p> Signup and view all the answers

    Ecthyma gangrenosum is a typical lesion associated with which infection?

    <p><strong>Pseudomonas aeruginosa</strong></p> Signup and view all the answers

    Pseudomonas aeruginosa is important in nosocomial infections as an opportunistic pathogen due to:

    <p><strong>Natural resistance to many antibiotics</strong></p> Signup and view all the answers

    Pseudomonas aeruginosa is intrinsically resistant to many antibiotics due to:

    <p><strong>Lack of cellular targets for antibiotics</strong></p> Signup and view all the answers

    Pseudomonas aeruginosa infections can lead to septicemia, which is characterized by:

    <p><strong>Hypotension and shock</strong></p> Signup and view all the answers

    Which antibiotic type is most effective against Pseudomonas aeruginosa in severe infections?

    <p>Cephalosporins</p> Signup and view all the answers

    Study Notes

    Neisseria meningitidis

    • Best growth on chocolate agar, enriched with nutrients.
    • Natural habitat includes the nasopharynx of healthy individuals.
    • Transmission occurs mainly via respiratory droplets.
    • Hematogenous dissemination leads to meningococcemia, a severe condition.
    • Rare opportunistic pathogens include Neisseria lactamica and Neisseria sicca.
    • Differentiated from gonococcus (Neisseria gonorrhoeae) by serological tests, particularly for capsular antigens.
    • Main serogroups causing disease in Spain are A, B, C, W, and Y.
    • Meningitis peaks in children aged 6 months to 2 years.
    • Most cases occur in winter and early spring.
    • First-line treatment for meningococcal bacteremia is intravenous penicillin.
    • Meningococcal C conjugate vaccine offers durable immunity.

    Enterobacteriaceae

    • Surface and capsular polysaccharide structures identified as O antigens.
    • Generally associated with gastrointestinal infections, including diarrheal diseases.
    • Enterotoxigenic Escherichia coli (ETEC) responsible for traveler's and infant diarrhea.
    • Bacillary dysentery caused primarily by Shigella species such as Shigella sonnei and Shigella flexneri.
    • Salmonella Typhi is the specific species linked to typhoid fever.
    • Bubonic plague symptom includes swollen lymph nodes (buboes).
    • Typhoid fever transmitted via contaminated food and water.
    • Flagella are identified with H antigens in enterobacteria.
    • Strict pathogenic E. coli strains can lead to uncommon infections in healthy individuals, including hemolytic uremic syndrome (HUS).
    • Gastroenteritis mainly transmits through ingestion of contaminated food.

    Pseudomonas aeruginosa

    • Ecthyma gangrenosum lesions are typically associated with Pseudomonas aeruginosa infections.
    • Important opportunistic pathogen in nosocomial infections due to its environmental adaptability and virulence factors.
    • Intrinsic resistance to multiple antibiotics arises from efflux pumps and protective outer membrane.
    • Infections can result in septicemia with rapid onset of fever, chills, and potential organ failure.
    • Most effective antibiotic for severe Pseudomonas infections includes piperacillin-tazobactam or cephalosporins.

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    Description

    Test your knowledge on Gram-negative cocci and rods including Neisseria spp, Pseudomonas aeruginosa, and the Enterobacteriaceae family. This quiz covers the characteristics, species, and pathogenicity of Neisseria genus, particularly Neisseria meningitidis and Neisseria gonorrhoeae.

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