Trypanosomes
40 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What type of cells are trypanosomes?

  • Hemoflagellates (correct)
  • Eukaryotes
  • Protozoa
  • Archaea

    • Which disease is caused by Trypanosoma brucei?

  • Malaria
  • Sleeping sickness (correct)
  • Tuberculosis
  • Chagas' disease

    • What is the vector of Trypanosoma brucei?

  • Tick
  • Tsetse fly (correct)
  • Flea
  • Mosquito

    • Where is Trypanosoma brucei gambiense commonly found?

    <p>West and Central Africa</p> Signup and view all the answers

    What is the morphology of Trypanosoma brucei in the blood of the vertebrate host?

    <p>Polymorphic, with three forms</p> Signup and view all the answers

    What is the location of the kinetoplast in Trypanosoma brucei?

    <p>Posterior end</p> Signup and view all the answers

    What is the stage of Trypanosoma that penetrates the blood vessel endothelium and invades extravascular tissues?

    <p>Long slender form</p> Signup and view all the answers

    What is the stage of Trypanosoma that is highly motile, short and stumpy?

    <p>Non-dividing metacyclic form</p> Signup and view all the answers

    What is the stage of Trypanosoma that has no free flagellum?

    <p>Short stumpy form</p> Signup and view all the answers

    What is the site of inoculation where Trypanosoma multiply by binary fission?

    <p>Site of inoculation</p> Signup and view all the answers

    What is the stage of Trypanosoma that is introduced into the mammalian host through the saliva of the vector tsetse fly?

    <p>Metacyclic trypomastigote</p> Signup and view all the answers

    In which part of the invertebrate host do the parasites develop into epimastigotes and attach to the cells of the glands?

    <p>Salivary glands</p> Signup and view all the answers

    What is the primary function of serologic techniques such as indirect fluorescent antibody test and ELISA?

    <p>To detect antibody in the sera</p> Signup and view all the answers

    What is the drug of choice for treating early stage trypanosomiasis?

    <p>Pentamidine</p> Signup and view all the answers

    Where is Trypanosoma brucei Rhodesiense commonly found?

    <p>East Africa</p> Signup and view all the answers

    What is the morphology of trypomastigote forms of Trypanosoma cruzi?

    <p>C-shape</p> Signup and view all the answers

    What is the habitat of amastigote forms of Trypanosoma cruzi?

    <p>All of the above</p> Signup and view all the answers

    What is the name of the disease caused by Trypanosoma cruzi?

    <p>Chagas disease</p> Signup and view all the answers

    What is the site of differentiation of trypomastigotes into intracellular amastigotes?

    <p>Near the site of inoculation</p> Signup and view all the answers

    What is the stage of Trypanosoma cruzi that attaches to the epithelium in the reduviid bug?

    <p>Metacyclic trypomastigote</p> Signup and view all the answers

    In which stage of the Trypanosoma cruzi life cycle does binary fission occur?

    <p>Amastigote</p> Signup and view all the answers

    What is the duration of the development of Trypanosoma cruzi in the reduviid bug?

    <p>10-15 days</p> Signup and view all the answers

    What is the fate of trypomastigotes in the bloodstream?

    <p>They do not replicate</p> Signup and view all the answers

    What is the site of multiplication of epimastigotes in the reduviid bug?

    <p>Hindgut</p> Signup and view all the answers

    What is the result of local replication of parasites and the influx of fluid and inflammatory cells into the infected area during acute infection?

    <p>Localised swelling and erythema</p> Signup and view all the answers

    How do trypanosomes disseminate throughout the body after the amastigotes transform into trypomastigotes?

    <p>By escaping host cells and entering the bloodstream</p> Signup and view all the answers

    What is the result of chronic infection in the gastrointestinal tract?

    <p>Massive dilatation of the esophagus and/or colon</p> Signup and view all the answers

    What is the purpose of xenodiagnosis in the diagnosis of Chagas disease?

    <p>To detect epimastigotes in the faeces, hemolymph, hindgut, and salivary glands of the bugs</p> Signup and view all the answers

    What is the characteristic of cardiac involvement in chronic Chagas disease?

    <p>Fibrosis within the heart muscle</p> Signup and view all the answers

    What is the characteristic of the tissue parasites during the chronic phase of Chagas disease?

    <p>Difficult to detect</p> Signup and view all the answers

    What is the primary site of invasion by trypomastigotes in the human host?

    <p>Cells near the site of inoculation</p> Signup and view all the answers

    What is the fate of trypomastigotes that enter the circulation?

    <p>They do not replicate</p> Signup and view all the answers

    What is the stage of Trypanosoma that is released into the circulation after multiplication by binary fission?

    <p>Trypomastigotes</p> Signup and view all the answers

    What is the location of the development of epimastigotes in the reduviid bug?

    <p>Midgut</p> Signup and view all the answers

    What is the duration of the development of Trypanosoma cruzi in the reduviid bug?

    <p>10-15 days</p> Signup and view all the answers

    What is the stage of Trypanosoma that is infectious to the human host?

    <p>Metacyclic trypomastigotes</p> Signup and view all the answers

    What is the site of transformation of trypomastigotes into amastigotes in the human host?

    <p>Cells near the site of inoculation</p> Signup and view all the answers

    What is the mode of transmission of Trypanosoma cruzi to the reduviid bug?

    <p>Through the blood of an infected animal</p> Signup and view all the answers

    What is the fate of metacyclic trypomastigotes in the reduviid bug?

    <p>They go with the faeces of the bug</p> Signup and view all the answers

    What is the site of attachment of epimastigotes in the reduviid bug?

    <p>Epithelium</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser