Microbiology Revision for NEET PG 2023: Parasitology, Bacteriology, and Virology
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Questions and Answers

Which of the following viruses causes slapped cheek appearance, gloves and stocking syndrome?

  • Adenovirus
  • Parvovirus B19 (correct)
  • Herpes simplex virus
  • Epstein-Barr virus
  • What is the shape of the Ebola virus?

  • Crown-like
  • Bullet-shaped
  • Cigarette-like or rod-shaped
  • Bowl of spaghetti (correct)
  • Which of the following viruses is double-stranded and has 11 segments?

  • Rotavirus (correct)
  • Parvovirus B19
  • Herpes simplex virus
  • Adenovirus
  • Which of the following parasites causes kala-azar with organomegaly?

    <p>Leishmania</p> Signup and view all the answers

    Which of the following diagnostic tests is used to detect Epstein-Barr virus infection?

    <p>Monospot test</p> Signup and view all the answers

    What is the size range of Cryptosporidium, a parasite that can cause diarrhea in immunocompromised patients?

    <p>4-6 microns</p> Signup and view all the answers

    What is the characteristic appearance of the liver abscess caused by Entamoeba histolytica?

    <p>Anchovy sauce appearance</p> Signup and view all the answers

    Which of the following is a characteristic feature of the Entamoeba histolytica trophozoite?

    <p>Cartwheel-shaped nuclei</p> Signup and view all the answers

    Which of the following is the recommended treatment for Balantidium coli infection?

    <p>Tetracycline or Metronidazole</p> Signup and view all the answers

    What is the characteristic motility pattern of Giardia lamblia trophozoites?

    <p>Falling leaf motility</p> Signup and view all the answers

    Which of the following is a distinctive feature of Trichomonas vaginalis?

    <p>Strawberry cervix</p> Signup and view all the answers

    Study Notes

    • Microbiology revision for NEET PG 2023 will cover high-yielding topics like parasitology, bacteriology, and virology in an image-based session.
    • Starting with parasitology, focusing on Entamoeba histolytica, known for causing flask-shaped ulcers and anchovy sauce appearance in the liver.
    • Entamoeba histolytica trophozoites show cartwheel-shaped nuclei, erythrophagocytosis of red blood cells, and cysts with chromatoid bodies composed of ribonucleoproteins.
    • Treatment for Entamoeba histolytica includes metronidazole and paromomycin.
    • Balantidium coli is a large ciliated parasite causing diarrhea, identified by its binucleated trophozoites and cysts with bean-shaped nuclei.
    • Treatment for Balantidium coli involves tetracycline or metronidazole.
    • Giardia lamblia, known as the "angry old man," presents with two nuclei in trophozoites, four pairs of flagella, and falling leaf motility in the duodenal lumen.
    • Treatment for Giardia lamblia includes metronidazole or 2g tinidazole.
    • Trichomonas vaginalis, the "fashionable auntie," causes strawberry cervix, only presents as trophozoites with twitching motility, and is treated with metronidazole.
    • Trypanosoma cruzi causes Chagas disease, presenting with a C-shaped organism, Romana's sign, megaesophagus (achalasia cardia), transmitted by the triatomine reduviid bug.
    • Trypanosoma brucei gambiense and rhodesiense cause sleeping sickness, with gambiense in East Africa and rhodesiense in West Africa, treated with pentamidine and suramin respectively.
    • Leishmania causes kala-azar with organomegaly, diagnosed by LD bodies in macrophages, treated with liposomal amphotericin B and miltefosine.
    • Immunocompromised patients with diarrhea may have Cryptosporidium, Cyclospora, or Isospora infections.
    • Cryptosporidium is 4-6 microns in size, Cyclospora is 8-12 microns, and Isospora may also be referred to as Cystoisospora.- Diarrhea is caused by adenovirus 4041 strains.
    • Shapes of viruses: bullet, kills; rabies, kills; Corona, crown-like; box, heavy with dumbbell DNA; tobacco mosaic virus, cigarette-like or rod-shaped; rotating wheel, Rota virus; star, Astro virus; bowl of spaghetti, Ebola; alien, adenovirus.
    • DNA viruses rule: all double-stranded except Parvo virus which is single-stranded and the smallest.
    • RNA viruses rule: all have one copy, single-stranded, unsegmented except Reo virus with two copies and double-stranded RNA.
    • Exceptions for RNA viruses: Rotavirus (Reo virus) with 11 segments, Arena virus with two segments.
    • DNA viruses summary: Parvovirus B19 causes slapped cheek appearance, gloves and stocking syndrome, joint pain, red cell aplasia.
    • Herpes viruses: multi-nucleation, molding, margination, Cowdry A inclusions in Zang smear.
    • Epstein-Barr virus: infects B cells via cd21 CR2 receptor, releases LMP1, Ebna 2, interleukin 10 causing infectious mononucleosis, glandular fever.
    • Downy cells in infectious mononucleosis are cd8 T cells resembling ballerinas.
    • Diagnostic tests for Epstein-Barr virus include the monospot test.

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    Description

    Prepare for NEET PG 2023 with a high-yielding revision session covering parasitology, bacteriology, and virology topics such as Entamoeba histolytica, Balantidium coli, Giardia lamblia, Trypanosoma species, Leishmania, and viral shapes and characteristics.

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