Microbiology Flashcards: Nocardia Species
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Questions and Answers

What are the general characteristics of Nocardia species? (Select all that apply)

  • Obligate aerobe (correct)
  • Catalase positive (correct)
  • Gram negative filamentous rod
  • Weakly acid fast (correct)
  • How does acid fast staining work?

    It uses carbol fuchsin stain that's taken up by bacteria with mycolic acids in their cell wall.

    What is the method of transmission for Nocardia species?

    Found in soil and associated with activities that allow dirt to get into wounds.

    Which groups are at risk for nocardiosis? (Select all that apply)

    <p>Immunocompromised patients</p> Signup and view all the answers

    What are the clinical presentations/complications of nocardiosis?

    <p>Pulmonary pneumonia with cavitary lesions, CNS brain abscess formation, and cutaneous indurated lesions.</p> Signup and view all the answers

    What activities can cause cutaneous nocardiosis?

    <p>Activities that can increase the chance of getting soil into open wounds, such as gardening or construction work.</p> Signup and view all the answers

    What is the treatment for nocardiosis?

    <p>Sulfonamides</p> Signup and view all the answers

    What is the mnemonic for differentiation of treatment between Nocardia and Actinomyces?

    <p>SNAP</p> Signup and view all the answers

    Study Notes

    General Characteristics of Nocardia Species

    • Gram-positive filamentous rods that are obligate aerobes.
    • Catalase and urease positive, exhibiting weak acid-fast properties.

    Acid Fast Staining Process

    • Involves using the carbol fuchsin stain, which is absorbed by bacteria with mycolic acids in their cell walls.
    • Mycolic acids consist of long-chain fatty acids characterized by two tails.

    Transmission Methods for Nocardia Species

    • Primarily found in soil; does not form spores, unlike many other bacteria.
    • Cutaneous nocardiosis is linked to activities where soil can enter wounds, such as gardening or construction.

    At-Risk Populations for Nocardiosis

    • Mainly affects immunocompromised individuals and shows a higher prevalence in men compared to women.

    Clinical Manifestations and Complications

    • Pulmonary: Presents as pneumonia with cavitary lung lesions.
    • CNS: Can lead to brain abscess formation.
    • Cutaneous: Results in indurated lesions accompanied by inflammatory reactions.

    Causes of Cutaneous Nocardiosis

    • Increased risk from activities that expose skin to soil, such as gardening, construction, and accidents.

    Treatment Options for Nocardiosis

    • Sulfonamides are the primary treatment method for infections caused by Nocardia.

    Treatment Differentiation Mnemonic

    • Use the mnemonic "SNAP" to remember: Sulfonamides for Nocardia, Penicillin for Actinomyces.

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    Description

    Dive into the world of Nocardia species with these flashcards. Learn about their general characteristics, the process of acid-fast staining, and more. Perfect for microbiology students looking to enhance their understanding of these unique bacteria.

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