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Questions and Answers
What cellular structure do erythromycin and streptomycin specifically target in bacteria?
What cellular structure do erythromycin and streptomycin specifically target in bacteria?
Why do antibiotics like Cipro not affect human cells?
Why do antibiotics like Cipro not affect human cells?
Which cellular structure is present in most bacteria but absent in human cells and is targeted by drugs like penicillin?
Which cellular structure is present in most bacteria but absent in human cells and is targeted by drugs like penicillin?
What was the first antibiotic to be discovered?
What was the first antibiotic to be discovered?
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What is a primary reason that some doctors predicted the end of infectious diseases in the early 1900's?
What is a primary reason that some doctors predicted the end of infectious diseases in the early 1900's?
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Which of the following statements best describes the main point of the chapter, according to the provided text?
Which of the following statements best describes the main point of the chapter, according to the provided text?
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What is the primary goal of antibiotic treatment?
What is the primary goal of antibiotic treatment?
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Based on the text, which of the following is a characteristic of antibiotics?
Based on the text, which of the following is a characteristic of antibiotics?
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What is the primary difference in structure between prokaryotic and eukaryotic cells?
What is the primary difference in structure between prokaryotic and eukaryotic cells?
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Which structure within a eukaryotic cell houses the majority of its DNA?
Which structure within a eukaryotic cell houses the majority of its DNA?
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How is the DNA organized in a prokaryotic cell?
How is the DNA organized in a prokaryotic cell?
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In the analogy comparing cells to buildings, what is analogous to the cubicles of an office building regarding eukaryotic cells?
In the analogy comparing cells to buildings, what is analogous to the cubicles of an office building regarding eukaryotic cells?
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What is the primary function of the plasma membrane?
What is the primary function of the plasma membrane?
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What are the main components of the cell's plasma membrane?
What are the main components of the cell's plasma membrane?
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Which of the following cellular structures is NOT present in prokaryotic cells?
Which of the following cellular structures is NOT present in prokaryotic cells?
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What is the function of membranes in eukaryotic cells?
What is the function of membranes in eukaryotic cells?
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Which of the following best describes the location of chromosomes in prokaryotic cells?
Which of the following best describes the location of chromosomes in prokaryotic cells?
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What is a key distinction between the cytoplasm of prokaryotic and eukaryotic cells according to the text?
What is a key distinction between the cytoplasm of prokaryotic and eukaryotic cells according to the text?
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Which statement accurately describes the evolutionary timeline of prokaryotic and eukaryotic cells?
Which statement accurately describes the evolutionary timeline of prokaryotic and eukaryotic cells?
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How does the size of prokaryotic cells generally compare to that of eukaryotic cells?
How does the size of prokaryotic cells generally compare to that of eukaryotic cells?
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What is a defining feature of eukaryotic cells that distinguishes them from prokaryotic cells in relation to organelles?
What is a defining feature of eukaryotic cells that distinguishes them from prokaryotic cells in relation to organelles?
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How do prokaryotic and eukaryotic cells differ in their chromosomal structure?
How do prokaryotic and eukaryotic cells differ in their chromosomal structure?
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Which of the following components is found in both prokaryotic and eukaryotic cells?
Which of the following components is found in both prokaryotic and eukaryotic cells?
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According to the content, what is the role of ribosomes in both prokaryotic and eukaryotic cells?
According to the content, what is the role of ribosomes in both prokaryotic and eukaryotic cells?
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What is the primary function of transport vesicles after they leave the endoplasmic reticulum (ER)?
What is the primary function of transport vesicles after they leave the endoplasmic reticulum (ER)?
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Which of the following characteristics is distinct to the smooth endoplasmic reticulum (ER)?
Which of the following characteristics is distinct to the smooth endoplasmic reticulum (ER)?
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Which of these is a key function of the smooth ER in liver cells?
Which of these is a key function of the smooth ER in liver cells?
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How does the smooth ER contribute to drug tolerance?
How does the smooth ER contribute to drug tolerance?
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What is the main role of the Golgi apparatus in cellular function, based on the analogy in the text?
What is the main role of the Golgi apparatus in cellular function, based on the analogy in the text?
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How do products from the ER reach the Golgi apparatus?
How do products from the ER reach the Golgi apparatus?
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What is the primary function of vesicles that bind with the plasma membrane?
What is the primary function of vesicles that bind with the plasma membrane?
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What is the purpose of the molecular identification tags that are added to proteins in the Golgi apparatus?
What is the purpose of the molecular identification tags that are added to proteins in the Golgi apparatus?
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From which organelle do lysosomes typically originate?
From which organelle do lysosomes typically originate?
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What is the purpose of digestive enzymes within a lysosome?
What is the purpose of digestive enzymes within a lysosome?
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From which ‘side’ of the Golgi apparatus do finished products depart for other locations in the cell?
From which ‘side’ of the Golgi apparatus do finished products depart for other locations in the cell?
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How do lysosomes assist in nutrient acquisition for single-celled protists?
How do lysosomes assist in nutrient acquisition for single-celled protists?
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Besides digestion, what other crucial function do lysosomes have with regards to cellular components?
Besides digestion, what other crucial function do lysosomes have with regards to cellular components?
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What is the significance of lysosomes in embryonic development?
What is the significance of lysosomes in embryonic development?
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What are the primary consequences of lysosomal storage diseases?
What are the primary consequences of lysosomal storage diseases?
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Which organelle is responsible for the formation of vacuoles?
Which organelle is responsible for the formation of vacuoles?
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What is the primary mechanism by which cholera bacteria cause harm in the human body?
What is the primary mechanism by which cholera bacteria cause harm in the human body?
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How does the spread of cholera from person to person typically occur?
How does the spread of cholera from person to person typically occur?
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What is the reason why the Bangladeshi population has developed resistance to cholera?
What is the reason why the Bangladeshi population has developed resistance to cholera?
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What specific biological target is altered by the cholera toxin in humans
What specific biological target is altered by the cholera toxin in humans
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What role does the environment play in the evolution of cholera resistance in Bangladesh?
What role does the environment play in the evolution of cholera resistance in Bangladesh?
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How does the study of cholera resistance in Bangladesh potentially benefit humans?
How does the study of cholera resistance in Bangladesh potentially benefit humans?
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What impact does the alteration of membrane proteins have on affected intestinal cells?
What impact does the alteration of membrane proteins have on affected intestinal cells?
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What survival advantage do the observed mutations provide to some individuals in Bangladesh?
What survival advantage do the observed mutations provide to some individuals in Bangladesh?
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Flashcards
Antibiotics
Antibiotics
Drugs that disable or kill infectious bacteria.
Penicillin
Penicillin
The first antibiotic discovered in 1920, revolutionizing medicine.
Bacterial ribosome
Bacterial ribosome
A structure in bacteria vital for protein production, targeted by antibiotics.
Erythromycin and streptomycin
Erythromycin and streptomycin
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Ciprofloxacin (Cipro)
Ciprofloxacin (Cipro)
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Cell wall synthesis disruption
Cell wall synthesis disruption
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Human versus bacterial chromosomes
Human versus bacterial chromosomes
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Understanding cells
Understanding cells
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Prokaryotic Cell
Prokaryotic Cell
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Eukaryotic Cell
Eukaryotic Cell
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Nucleus
Nucleus
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Nucleoid
Nucleoid
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Organelles
Organelles
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Plasma Membrane
Plasma Membrane
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Membrane Structure
Membrane Structure
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Comparison of Cells
Comparison of Cells
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Smooth ER
Smooth ER
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Function of Smooth ER
Function of Smooth ER
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Lipid Synthesis
Lipid Synthesis
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Drug Tolerance
Drug Tolerance
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Golgi Apparatus
Golgi Apparatus
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Transport Vesicles
Transport Vesicles
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Protein Modification
Protein Modification
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Golgi Stack Structure
Golgi Stack Structure
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Cytoplasm
Cytoplasm
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Chromosomes
Chromosomes
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Ribosomes
Ribosomes
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Membrane-bound Organelles
Membrane-bound Organelles
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Cell Size
Cell Size
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Evolution of Cells
Evolution of Cells
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Lysosome
Lysosome
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Function of Lysosomes
Function of Lysosomes
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Lysosomal Enzymes
Lysosomal Enzymes
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Food Vacuoles
Food Vacuoles
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Lysosomal Storage Diseases
Lysosomal Storage Diseases
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Tay-Sachs Disease
Tay-Sachs Disease
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Vacuoles
Vacuoles
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Role in Embryonic Development
Role in Embryonic Development
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Natural Selection
Natural Selection
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Genetic Variations
Genetic Variations
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Bacterial Resistance
Bacterial Resistance
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Cholera
Cholera
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Mutation
Mutation
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Plasma Membrane Proteins
Plasma Membrane Proteins
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Environmental Adaptation
Environmental Adaptation
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Evolutionary Study
Evolutionary Study
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Study Notes
The Microscopic World of Cells
- Cells are miniature marvels, sophisticated even at microscopic size
- Organisms can be single-celled (prokaryotes, protists) or multicellular (plants, animals, fungi)
- Cells of the body are specialized for different functions
- Cells constantly interact and work together efficiently
Antibiotics: Drugs That Target Bacterial Cells
- Antibiotics disable or kill bacteria.
- Penicillin was the first antibiotic, discovered in 1920.
- Antibiotics dramatically reduced fatality rates from bacterial diseases (pneumonia, surgical infections) saving millions of lives.
- The goal of antibiotics is to kill bacteria without harming human cells.
- Antibiotics specifically target structures found only in bacterial cells (e.g., bacterial ribosomes, bacterial chromosome structures, bacterial cell walls).
Comparing Prokaryotic and Eukaryotic Cells
- Prokaryotic cells are smaller and simpler, found in Bacteria and Archaea.
- Eukaryotic cells are larger and more complex, found in protists, plants, fungi and animals.
- Prokaryotic cells lack membrane-bound organelles, while eukaryotic cells have organelles.
- Both cell types have ribosomes which differ slightly in structural features.
The Plasma Membrane
- The plasma membrane separates the cell from its surroundings.
- The structure of phospholipids is suitable for creating membranes
- Phospholipid bilayers consist of hydrophilic heads and hydrophobic tails.
- The membrane has proteins embedded in the bilayer.
- Membranes are fluid mosaics; molecules (phospholipids and proteins) can move around.
What Makes a Superbug?
- Superbugs (like MRSA) are bacteria resistant to many antibiotics.
- Some superbugs use proteins (PSMs) to damage human immune cells.
- MRSA infections are often found in hospitals, gyms, schools
Cell Surfaces
- Plant cells have a rigid cell wall made of cellulose
- Plant cells are connected by channels in the cell wall
- Animal cells lack a rigid cell wall
- Animal cells have an extracellular matrix and cell junctions.
The Nucleus and Ribosomes: Genetic Control of the Cell
- The nucleus is the control center of the cell
- Genes (stretches of DNA) store information for protein production
- Proteins are the workers in the cells. The perform most cellular functions.
- Chromatin is DNA wrapped around proteins.
- Chromosomes are long strands of DNA.
- Cells use the information in DNA to build proteins.
- Ribosomes synthesize proteins.
Ribosomes
- Ribosomes are responsible for protein synthesis.
- Ribosomes can be free-floating in the cytosol or attached to the endoplasmic reticulum.
- Ribosomes' components are made in the nucleus and exported to the cytoplasm for function
The Endomembrane System:
- Organelles (ER, Golgi apparatus, lysosomes, vacuoles) are part of the Endomembrane system
- The endoplasmic reticulum is a main manufacturing facility in the cell. It creates a variety of molecules, including membranes.
- Rough ER has ribosomes and makes proteins.
- Smooth ER makes lipids
- The Golgi Apparatus packages and modifies proteins.
- Vesicles transport materials between parts of the endomembrane system.
Lysosomes
- Lysosomes break down large molecules or organelles inside the cell.
- Lysosomes contain digestive enzymes
- They are used during embryonic development and in cell recycling.
- Defects in lysosomal enzymes cause lysosomal storage diseases which are often fatal.
Vacuoles
- Vacuoles are sacs made of membrane that bud off from the ER or Golgi apparatus.
- Contractile vacuoles pump out excess water
- Central vacuoles are large in plant cells and aid in plant growth, storage and protection
Chloroplasts and Mitochondria
- Chloroplasts perform photosynthesis; converting light energy to chemical energy (sugars).
- Mitochondria perform cellular respiration (generating energy from sugars; converting food energy to ATP - chemical energy).
- Both organelles contain their own DNA and ribosomes.
- Mitochondria and chloroplasts evolved from free-living bacteria.
The Cytoskeleton
- The cytoskeleton is a network of protein fibers that provides structural support and movement in the cell
- Microtubules are a type of protein fiber in the cytoskeleton
- Intermediate filaments and microfilaments and types of protein fibers in the cytoskeleton
- The cytoskeleton helps keep cells from collapsing, allows specific molecules to move within cells.
Cilia and Flagella
- Cilia or flagella are extensions from eukaryotic cells that help with movement
- Cilia are short, numerous, and appear in a coordinated beating motion
- Flagella are long, and function in an undulating, whip-like motion
- Cilia and flagella share a similar internal microtubule structure
The Evolution of Bacterial Resistance in Humans
- Natural selection favors bacteria with advantageous mutations (resistance).
- Repeated exposure to antibiotics can lead to resistance in bacterial populations.
- Variations in genes related to the plasma membrane proteins may confer resistance to cholera.
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Description
Test your understanding of antibiotics and their effects on bacterial cells versus human cells in this microbiology quiz. Explore key concepts such as cellular structures targeted by different antibiotics, the history of antibiotic discovery, and the differences between prokaryotic and eukaryotic cells. Perfect for students studying microbiology or pharmacology.