Microbiology and Parasitology Review

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10 Questions

Which of the following parasites can cause cysticercosis?

Taenia solium

What is the intermediate host of Taenia saginata?

Cow

What is the drug of choice for treating taeniasis and cysticercosis?

Albendazole

How is Taenia solium typically transmitted?

Through ingestion of larvae in pork

What is a characteristic feature of Taenia solium scolex?

Has 4 suckers and a circle of hooks around the rostellum

What is the main difference between Taenia saginata and Taenia solium scolex?

Presence or absence of hooks and rostellum

What is the consequence of rupturing a Taenia solium cyst?

Anaphylactic shock

Which of the following parasites does NOT cause cysticercosis?

Taenia saginata

How is Diphyllobothrium latum typically transmitted?

Through ingestion of raw or undercooked fish

What is a characteristic feature of Taenia saginata scolex?

Has 4 suckers and no hooks or rostellum

Study Notes

Medical Parasitology

  • Parasitism: an organism (parasite) gains food and shelter from another (host) which suffers from the relationship
  • Endoparasite: inside the body, connotes infection
  • Ectoparasite: outside the body, connotes infestation
  • Obligate parasite: type of parasite that requires host
  • Facultative parasite: may exist as free living or parasitic within host
  • Vector: living invertebrate carrier that transmits pathogen

Cutaneous/ Mucocutaneous Leishmaniasis

  • Causes skin ulcers, visceral leishmaniasis, spiking fevers, hepatosplenomegaly, and pancytopenia
  • Tx: Amphotericin B, sodium stibogluconate
  • Key Terms: Oriental sore, Espundia, Kala-azar

Babesiosis

  • Transmission: bite of Ixodes tick
  • Disease: Babesiosis, fever and hemolytic anemia, predominantly in northeastern and north central United States
  • Key Terms: Maltese Cross
  • Treatment: Atovaquone + Azithromycin

Plasmodium spp. (Malaria)

  • Transmission: bite of Anopheles mosquito
  • Disease: Malaria, cyclic fevers, headache, anemia, splenomegaly, and hypoglycemia in severe disease
  • Key Terms: Trophozoites, Cyst, Flagellated, Nonflagellated
  • Treatment: Chloroquine (if sensitive), mefloquine, doxycycline, or atovaquone/proguanil (if resistant)

Toxoplasmosis

  • Transmission: ingestion, transplacental
  • Disease: Congenital toxoplasmosis
  • Key Terms: Heterophil-negative mononucleosis

Naegleria fowleri

  • Transmission: swimming in warm freshwaters, enters CNS through olfactory nerve via cribriform plate
  • Disease: Rapidly fatal meningoencephalitis
  • Key Terms: Acid fast oocysts, Prevention (e.g., filtering), nitazoxanide

Trypanosoma cruzi (Chagas disease/American Trypanosomiasis)

  • Transmission: feces of reduviid bug/triatomine insect on bite
  • Disease: Dilated cardiomyopathy with apical aneurysm, megacolon, megaesophagus

Nematodes

  • Routes of infection:
    • Ingested: Enterobius, Ascaris, Toxocara, Trichinella, Trichuris
    • Mnemonic: You’ll get sick if you EAT These Things!
  • Examples: Taenia solium, Taenia saginata, Diphyllobothrium latum

Comprehensive review of microbiology and parasitology, including medical parasitology, definition of terms, and types of parasitism.

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